Impact of conventional and advanced therapies in functional hair follicular regeneration in pesticide-induced hair loss: a Pharmacological perspective of review

Authors

Abstract

This review highlights the impact of conventional, advanced, and gene therapy in hair follicular regeneration in pesticide-induced hair loss. Most states in India and abroad have agricultural land, where people of different age groups work and are exposed to various pesticides that affect their health and cause hair loss. Alopecia, thinning, and shedding arise from particular chemicals in pesticides that disrupt normal hair follicle function, leading to increasing concerns about hair loss due to pesticide exposure. Hormonal disruptions, oxidative damage, and inflammatory responses are a few of the mechanisms by which pesticides harm the scalp and hair roots. In this review, the authors have tried to explore the underlying mechanism of how the pesticides affect hair growth cycles and follicular health by analysing their toxicological impact, shedding light on the mechanisms that cause hair loss as well as the therapeutic effectiveness of various therapies including herbals like ginseng, green tea, hibiscus, and castor oil etc. those are able to counteract the negative impacts of pesticides with their molecular mechanism of action that will be helpful and will pave the way for further research in the field of hair growth and regeneration.

Keywords: pesticides, follicular damage, herbal bioactive, hair regeneration, advanced therapy, gene therapy

Keywords:

pesticides, follicular damage, herbal bioactive, hair regeneration, advanced therapy, gene therapy

DOI

https://doi.org/10.22270/jddt.v15i7.7293

Author Biographies

Trilochan Satapathy , Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Pratibha Dhiwar , Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Poonam Sahu , Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Kamaksha Tiwari, Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Laxmi Sahu, Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

Columbia Institute of Pharmacy, Village Tekari, Near Vidhansabha, Raipur-493111, C.G., India.

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2025-07-15
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Satapathy T, Dhiwar P, Sahu P, Tiwari K, Sahu L. Impact of conventional and advanced therapies in functional hair follicular regeneration in pesticide-induced hair loss: a Pharmacological perspective of review. J. Drug Delivery Ther. [Internet]. 2025 Jul. 15 [cited 2026 Jan. 13];15(7):233-56. Available from: https://jddtonline.info/index.php/jddt/article/view/7293

How to Cite

1.
Satapathy T, Dhiwar P, Sahu P, Tiwari K, Sahu L. Impact of conventional and advanced therapies in functional hair follicular regeneration in pesticide-induced hair loss: a Pharmacological perspective of review. J. Drug Delivery Ther. [Internet]. 2025 Jul. 15 [cited 2026 Jan. 13];15(7):233-56. Available from: https://jddtonline.info/index.php/jddt/article/view/7293

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