Prevalence of Hepatitis B Core Antibody in Sudanese Random Blood Donors at Khartoum state, 2022

  • Mohamed Hassan Osman Ebar Faculty of Medical Laboratory Science, National University, Sudan
  • Hassan Abass Mohamed Abdalla Faculty of Medical Laboratory Science, National University, Sudan
  • Malaz Almoiz Atiya Osman University of El Imam El Mahdi
  • Albara Ahmed Faculty of Medical Laboratory Science, National University, Sudan

Abstract

Background: Hepatitis B virus is a DNA virus belonging to the Hepadnaviridae family attacking the liver and can cause both acute and chronic disease.  The aim of this study was to determine the prevalence of Hepatitis B core antibody in Sudanese random blood donors.


Materials and methods: The study was descriptive cross-sectional study conducted at Ibn Sina Specialized Hospital, Khartoum, Sudan during the period from May 2022 to September 2022. Blood samples were collected from 100 random blood donors. A total of three ml of whole blood were collected from each participant in plain tube. Hepatitis B core antibody test was done by using biochemistry analyzer (Cobas 411).


Results: The results of this study revealed that all blood donors were negative for HBsAg but 51% of them were positive for HBcAb. The mean average of hepatitis B core antibody in blood donors was 0.984 ± 0.950, where the mean average of hepatitis B surface antigen was 0.685± 0.170. The educational background had a positive correlation with the prevalence of hepatitis B core antibody.


Conclusion: This study concluded that the prevalence of hepatitis B core antibody in blood donors was high.


Keywords: Hepatitis B virus infection, hepatitis B core antibody, enzyme linked immunosorbent assay, blood donation, blood transfusion, random blood donors

Keywords: Hepatitis B virus infection, hepatitis B core antibody, enzyme linked immunosorbent assay, blood donation, blood transfusion, random blood donors

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Author Biographies

Mohamed Hassan Osman Ebar, Faculty of Medical Laboratory Science, National University, Sudan

Faculty of Medical Laboratory Science, National University, Sudan

Hassan Abass Mohamed Abdalla, Faculty of Medical Laboratory Science, National University, Sudan

Faculty of Medical Laboratory Science, National University, Sudan

Malaz Almoiz Atiya Osman, University of El Imam El Mahdi

University of El Imam El Mahdi

Albara Ahmed, Faculty of Medical Laboratory Science, National University, Sudan

 Alfajri College, Sudan

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Ebar M, Abdalla HAM, Osman MAA, Ahmed A. Prevalence of Hepatitis B Core Antibody in Sudanese Random Blood Donors at Khartoum state, 2022. JDDT [Internet]. 15Nov.2022 [cited 9Dec.2022];12(6):44-7. Available from: https://jddtonline.info/index.php/jddt/article/view/5785

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