Application of Sigma Metrics for Evaluating Analytical Performance of HbA1C Testing on D10- HbA1C Analyzer

  • Bibek Pun Magar Department of Biochemistry, Karnali academy of Health and Sciences
  • Amit Thapa Province Public Health Laboratory, Karnali Province Surkhet, Nepal
  • Shreeman Acharya Rapti Academy of Health Sciences, Ghorahi, Dang, Nepal
  • Narayan Ghimire School of Health and Allied Sciences, Pokhara University, Pokhara, Nepal
  • Sanjiv Kumar Pandey Nepal Pharmacy Council, Kathmandu, Nepal
  • Rabindra Kumar Rokaya School of Pharmacy, Karnali Academy of Health Sciences, Jumla,Nepal
  • Suman Lamichhane Shree Medical and Technical College, Bharatpur, Nepal (Purvanchal University, Nepal)

Abstract

In this study, analyzed HbA1C over a period of 6 months. Six Sigma improves the quality of process outputs by analyzing and eliminating the source of defects and reducing variability in manufacturing and business practices. In terms of clinical laboratory, the identification of test with low Sigma values (< 3σ) indicate that actions should be taken to improve analytic quality or the laboratory should use alternate methods and reagents. Our study showed methodologies for HbA1C is of world class performance achieving Sigma value ˃6, to maintain and improve this frequency of QC should be run as rule as per the westguard QC rule. Sigma metrics helps to assess analytical methodologies and augment laboratory performance. It acts as a guide for planning quality control strategy. It can be a self -assessment tool regarding the functioning of clinical laboratory. Using Six Sigma techniques, able to identify problem areas as well as recurring issues that affect the overall quality expectation of laboratory result.


Keywords: HbA1C, Six Sigma, Six Sigma values

Keywords: HbA1C, six sigma, sigma values

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Author Biographies

Bibek Pun Magar, Department of Biochemistry, Karnali academy of Health and Sciences

Department of Biochemistry, Karnali Academy of Health Sciences, Jumla, Nepal

Amit Thapa, Province Public Health Laboratory, Karnali Province Surkhet, Nepal

Province Public Health Laboratory, Karnali Province Surkhet, Nepal

Shreeman Acharya, Rapti Academy of Health Sciences, Ghorahi, Dang, Nepal

Rapti Academy of Health Sciences, Ghorahi, Dang, Nepal

Narayan Ghimire, School of Health and Allied Sciences, Pokhara University, Pokhara, Nepal

School of Health and Allied Sciences, Pokhara University, Pokhara, Nepal

Sanjiv Kumar Pandey, Nepal Pharmacy Council, Kathmandu, Nepal

Nepal Pharmacy Council, Kathmandu, Nepal

Rabindra Kumar Rokaya, School of Pharmacy, Karnali Academy of Health Sciences, Jumla,Nepal

School of Pharmacy, Karnali Academy of Health Sciences, Jumla,Nepal

Suman Lamichhane, Shree Medical and Technical College, Bharatpur, Nepal (Purvanchal University, Nepal)

Shree Medical and Technical College, Bharatpur, Nepal (Purvanchal University, Nepal)  

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Magar B, Thapa A, Acharya S, Ghimire N, Pandey SK, Rokaya R, Lamichhane S. Application of Sigma Metrics for Evaluating Analytical Performance of HbA1C Testing on D10- HbA1C Analyzer. JDDT [Internet]. 15Apr.2024 [cited 12Jul.2024];14(4):27-2. Available from: https://jddtonline.info/index.php/jddt/article/view/6424