Comprehending the Presence and Application of Antiradicals and Antioxidants within the Human Body
Abstract
A substance that prevents other molecules from oxidising is known as an antioxidant1. A chemical process called oxidation can generate free radicals, which can set off a series of events that can harm cells. Ascorbic acid, an antioxidant, stops these cascades of events. Reactive-oxygen species (ROS) are produced in excess by plants and animals as a result of various abiotic stressors. ROS are extremely sensitive and toxic, damaging proteins, lipids, carbohydrates, and DNA as a result, which causes oxidative stress. This oxidative-stress damages tissues and contributes to a broad range of illnesses2. Antioxidants counteract the effects of ROS and aid in disease prevention by balancing their effects. Antioxidants can be naturally occurring or synthetic. Common cancer preventatives are ingested through diet because they are present in organic foods, veggies, and flavours. Additionally, several designed cancer preventative substances like BHT and BHA prevent oxidation. The search for non-toxic cancer prevention agents has gotten stronger in recent years, nonetheless, as it has been determined that these synthetic cancer prevention agents pose risks to people.
Keywords: Parkinson's disease, Parkinson's cancer, ascorbic acid, and tocopherols.
Keywords:
Parkinson's disease, Parkinson's cancer, ascorbic acid, tocopherolsDOI
https://doi.org/10.22270/jddt.v12i4-S.5541References
Sindhi V, et.al. Potential applications of antioxidants-A review. Journal of Pharmacy Research. 2021; 7:828-835.
Gebrehiwot K, et. al. Association of Total Levels of Serum Antioxidants with Periportal Fibrosis and Intensity of Schistosomamansoni Infections in Cheretee, North East Ethiopia. J Bacteriol Parasitol. 2020; 6:220.
Merve C and Elmas C. The Effects of Oxidative Stress and Some of the Popular Antioxidants on Reproductive System: A Mini Review. J Nutr Food Sci. 2016; 6:464.
Kohen R and Nyska A. Invited Review: Oxidation of Biological Systems: Oxidative Stress Phenomena, Antioxidants, Redox Reactions, and Methods for Their Quantification. Toxicol Pathol. 2018; 30:620-650.
Eken ZE. Antioxidants. Pigmentary Disorders. 2015; 1:163.
Uttara B. Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options. Curr Neuro pharmacol. 2019; 7:65-74.
Maritim AC, et.al. Diabetes, oxidative stress, and antioxidants: A review. J Biochem Mol Toxicol. 2013; 17:24-38.
Blokhinaa O. Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review. Ann Bot. 2013; 91:179-194.
Burton GW and Ingold KU. Beta-Carotene: an unusual type of lipid antioxidant. Science. 1984; 224:569-573.
Knight JA. Review: Free Radicals, Antioxidants, and the Immune System. Ann Clin Lab Sci. 2010; 30:145-158.
Shetty BS, Wound Healing and Indigenous Drugs: Role as Antioxidants: A Review. Medical and Health Sciences. 2013; 2:5-16.
Sharma N. Free Radicals, Antioxidants and Disease. Biol Med. 2014; 6:214.
Brewer MS. Natural Antioxidants: Sources, Compounds, Mechanisms of Action, and Potential Applications. Comprehensive Reviews in Food Science and Food Safety. 2011; 10:221-247.
Rao AV and Agarwal S. Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: A review. Nutrition Research. 1999; 19:305-325.
Shing WL. Colourful Antioxidants for Environmental Toxicity Assessment. J Biomol Res Ther 2013; 2: e114.
Khan Z, et.al. Low Velocity Impact of Filament-Wound Glass-Fiber Reinforced Composite Pipes. J Material Sci Eng. 2016; 5:253.
Traber MG. Vitamin E, Antioxidant and Nothing More. Free Radic Biol Med. 2007; 43:4–15.
Falowo AB. Natural antioxidants against lipid–protein oxidative deterioration in meat and meat products: A review. Food Research International. 2014; 64:171-181.
Halliwell B. Antioxidants in Human Health and Disease. Annual Review of Nutrition. 1996; 16:33-50.
Tandon S, et.al. Antioxidants: Potential Inducers of Gene Expression through CAMP Dependent Pathway. J Blood Disord Transfus. 2012; S3-006.
Gianni Paulis, et.al. Pentoxifylline Associated with Other Antioxidants (Multimodal Therapy) on Patients with Peyronie's Disease. Results of a Controlled Study. Andrology. 2014; 3:123.
Butnariu M. The Impact of Physical Processes and Chemicals of the Antioxidants (Bioactivity Compounds). J Bioequiv Availab. 2013; 5:e44.
Osuna-Martínez U. Cactus (Opuntiaficus-indica): A Review on its Antioxidants Properties and Potential Pharmacological Use in Chronic Diseases. Nat Prod Chem Res 2014, 2:153.
Eldahshan OA, et.al. Medicinal Plants and Addiction Treatment. Med Aromat Plants. 2016; 5: 260.
Aydemir LY and Yemenicioglu A. Antioxidant Activity of Pulse Hydrocolloids: Classical Screening Methods Depending on Water Soluble Phenolic Antioxidants Need Revision to Measure True Antioxidant Potential of Pulses. J Plant Biochem Physiol. 2014; 2:131.
Singh S and Immanuel G. Extraction of Antioxidants from Fruit Peels and its Utilization in Paneer. J Food Process Technol. 2014; 5:349.
Bhattacharya M and Chakraborty S. Free Radicals and Naturally Occurring Antioxidants. Journal of Pharmacognosy and Phytochemistry. 2015; 3:1-7.
Kulikova OI, et.al. Effects of Antioxidants on the Viability of the Human Neuroblastoma SH-SY5Y Cell Culture under the Conditions of Heavy Metal Toxicity. Biol Med. 2016; 8:305.
Amer SAM, Protective Role of Some Antioxidants on Arsenic Toxicity in Male Mice: Physiological and Histopathological Perspectives. Biol Med. 2016; 8(1):266.
Zhang E et al., Effects of Long-term Nitrogen and Organic Fertilization on Antioxidants Content of Tomato Fruits. J Hortic. 2016; 3(2):172.
Published
Abstract Display: 320 
PDF Downloads: 410 PDF Downloads: 17 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.