Formulation and Evaluation of Essential Oil Encapsulated Mosquito Repellent Gel

Authors

  • Pramod Kumar Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow- 227202, India
  • Rohit Kumar Bijauliya BIU College of Pharmacy, Bareilly International University, Bareilly-243006, Uttar Pradesh, India
  • Balbir Singh BIU College of Pharmacy, Bareilly International University, Bareilly-243006, Uttar Pradesh, India
  • Priti Yadav Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow- 227202, India
  • Wasim Ahmed Khan Modern College of Pharmacy, Kochhabhawar, Jhansi-284128, Uttar Pradesh, India

Abstract

Mosquitoes can be found in almost every country. Many mosquito repellents have been introduced to the market in order to combat them. The mosquitos, on the other hand, developed a resistance to them. Not only that, but users are experiencing a variety of known and unknown negative side effects. As a result, a poly herbal insect repellent gel has been developed in an attempt to give dependable, long-lasting, and full protection from mosquito bites by destroying them. Three essential oils were included in the formulation of the mosquito repellent gel, as well as polymers such as tween 80, span 20, Carbopol 934, and triethanolamine. They were assessed based on their actions. Spreadibility, viscosity, swelling index, and mosquito repellent activity were used to evaluate the prepared mosquito repellent gel. As acceptance criterion, all parameters received favorable responses. The rheological study and mosquito repellent activity are highly correlated. Although the results of the current trials are promising, there is still room for more pharmacokinetic research.

Keywords: Essential Oil, Emulsion Formulations, Gel, Mosquito Repellent Activity

Keywords:

Essential Oil, Emulsion Formulations, Gel, Mosquito Repellent Activity

DOI

https://doi.org/10.22270/jddt.v12i1.5265

Author Biographies

Pramod Kumar, Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow- 227202, India

Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow- 227202, India

Rohit Kumar Bijauliya, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, Uttar Pradesh, India

BIU College of Pharmacy, Bareilly International University, Bareilly-243006, Uttar Pradesh, India

Balbir Singh, BIU College of Pharmacy, Bareilly International University, Bareilly-243006, Uttar Pradesh, India

BIU College of Pharmacy, Bareilly International University, Bareilly-243006, Uttar Pradesh, India

Priti Yadav, Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow- 227202, India

Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow- 227202, India

Wasim Ahmed Khan, Modern College of Pharmacy, Kochhabhawar, Jhansi-284128, Uttar Pradesh, India

Modern College of Pharmacy, Kochhabhawar, Jhansi-284128, Uttar Pradesh, India

References

Imeda C, Katani S, Kitu A, Kitufe N, Magesa S, Magogo F, Malebo H, Wiketye V: Repellence effectiveness of essential oils from some Tanzanian Ocimum and Hyptis plant species against afro-tropical vectors of malaria and lymphatic filariasis. Journal of Medicinal Plants Research 2013; 7:653-660

Makhaik M, Naik SN, Tewary DK: Evaluation of anti-mosquito properties of essential oils. Journal of Scientific and Industrial Research 2005; 64:129-133

Adeogun AO, Adewuyi GO, Etatuvie SO, Fawehinmi AB, Lawal HO: Bioassay of Herbal Mosquito Repellent Formulated from the Essential Oil of Plants. Journal of Natural Products 2012; 5:109-115

Mohomed AA, Tarek IAAM, Zarrag IAA: Larvicidal and repellent effect of some Tribulus terrestris L., (Zygophyllaceae) extracts against the dengue fever mosquito, Aedes aegypti (Diptera: Culicidae). Journal of Saudi Chemical Society 2012: 1-7.

Ranasinghe MSN, Arambewela L and Samarasinghe S: Development of Herbal Mosquito Repellent Formulations. Int J Pharm Sci Res 2016; 7(9): 3643-48. https://doi.org/10.13040/IJPSR.0975-8232.7(9).3643-48

Shivhare UD, Jain KB, Mathur VB et al. Formulation development and evaluation of diclofenac sodium gel using water soluble polycrylamide polymer. Digest Journal of Nanomaterials and Biostructures 2009; 4:285-290

Charles M. Heard, Simon J. Ketoprofen release from permeation across & rheology of simple gel formulation that stimulate increasing dryness; Int. Journal of pharmaceutics, 2003; 268:37-45 https://doi.org/10.13040/IJPSR.0975-8232.7(9).3643-48

Bettini, P. L. Catellani, P. Santi, G. Massimo Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate, Journal of Controlled Release, 2001: 70(3):383-391. https://doi.org/10.13040/IJPSR.0975-8232.7(9).3643-48

Guterres Silvia S, Marta P. Alves. Human skin penetration & distribution of Nimesulide from hydrophilic gels containing nanocarriers, Int. journal of pharmaceutics, 2007; 341:215-220. https://doi.org/10.13040/IJPSR.0975-8232.7(9).3643-48

Alberto B. Clinical pharmacokinetics & metabolism of Nimesulide. Inflammo Pharmacology, 2001; 9:81-89. https://doi.org/10.1163/156856001300248353

Published

2022-01-15
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How to Cite

1.
Kumar P, Bijauliya RK, Singh B, Yadav P, Khan WA. Formulation and Evaluation of Essential Oil Encapsulated Mosquito Repellent Gel. J. Drug Delivery Ther. [Internet]. 2022 Jan. 15 [cited 2026 Jan. 14];12(1):23-9. Available from: https://jddtonline.info/index.php/jddt/article/view/5265

How to Cite

1.
Kumar P, Bijauliya RK, Singh B, Yadav P, Khan WA. Formulation and Evaluation of Essential Oil Encapsulated Mosquito Repellent Gel. J. Drug Delivery Ther. [Internet]. 2022 Jan. 15 [cited 2026 Jan. 14];12(1):23-9. Available from: https://jddtonline.info/index.php/jddt/article/view/5265