Recent Development in Floating Drug Delivery System: An Overview
Abstract
Floating medicines work well to increase drug absorption in the stomach. On the basis of current literature, a drug for a novel drug delivery system (NDDS) is established to explicate the floating drug delivery system (FDDS). The most recent FDDS progress involves the formulation as well as physiological aspects that may affect gastric retention and formulation. This review also discusses certain ways of producing a floating system, as well as evaluation methods, characterization, and classification for the FDDS pharmaceutical dosage form. By overcoming physiological hurdles such as short stomach residence times and unexpected gastric emptying times, scientific and technological achievements have been made in the study and development of controlled-release oral drug delivery systems in recent years. So, in general, float dose systems are key technological medication delivery systems that have a stomach-retentive nature and provide a variety of options. Floating drug delivery systems (FDDS), also known as hydro dynamically balanced systems (HBS), swelling and expanding systems, polymeric bio-adhesive systems, modified-shape systems, high-density systems, and other delayed gastric emptying devices are now used to extend the GRT. The latest technological breakthroughs of FDDS, including patented delivery methods and commercialized products, are covered in this study, as well as their advantages and future possibilities for oral controlled drug administration.
Keywords- A novel drug gastrointestinal tract, types of FDDS, gastric residence time, evaluation of FDDS
Keywords:
A novel drug gastrointestinal tract, types of FDDS, gastric residence time, evaluation of FDDS
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References
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12. Kamalakkannan V, Pyratchikody A, Viswanadhan VP,"Enhancement of Drugs bioavailability by Floating Drug Delivery System-A Review.''Int. J. Drug Delivery.2011; 3(4): 558-570.
13. Zubedi S.S, Mohammed S . floating tablet and its polymers, Journal of Drug Delivery & Therapeutics. 2018; 8(5-s):16-24 https://doi.org/10.22270/jddt.v8i5-s.1928
14. Kumar G. Natural Polymers in the Development of Floating Drug Delivery Systems: A Review, Int. J. Pharm. Life Sci, 2013; 2(4):165-178. https://doi.org/10.3329/ijpls.v2i4.17116
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20. Kaushik AY, Tiwari A K and Gaur A. Role of Excipients and polymeric advancements in preparation of floating drug delivery systems, Int J Pharm Investig. 2015; 5(1):1-12. https://doi.org/10.4103/2230-973X.147219
21. Pakhale NV, Gondkar SB, Saudagar RB, Effervescent Floating Drug Delivery System: A Review, Journal of Drug Delivery and Therapeutics. 2019; 9(3-s):836-838. https://doi.org/10.22270/jddt.v9i4-A.3490
22. Padhan et al. Floating Oral In-situ Gel, A Comprehensive Approach of Gastroretentive Drug Delivery System: A Review, IJPSR. 2019; 10(9):4026-4039.
23. Kumari B. Recent Development in Floating Drug Delivery System: A Review, Asian Journal of Pharmacy and Pharmacology. 2018; 4(2):131-139. https://doi.org/10.31024/ajpp.2018.4.2.6
24. Jaimini R, Gupta MK, Sharma V. A Review on Formulation and Evaluation of Gastroretentive Floating Tablet of Nifedipin, Journal of Drug Delivery and Therapeutics. 2019 Jul 15; 9(4):651-6.
25. Nur A.O, Zhang J.S. Captopril floating and/or bioadhesive tablets: design and release kinetics.Drug Dev Ind Pharm. 2000; 26:965-969. https://doi.org/10.1081/DDC-100101323
26. Sopyan I, Sriwidodo, Wahyuningrum R, Norisca Aliza P. A review: Floating drug delivery system as a tool to improve dissolution rate in gastric, Int J Appl Pharm. 2020; 12(4):51-4. https://doi.org/10.22159/ijap.2020v12i4.38415
27. Sharma N, Agarwal D, Gupta MK and Khinchi MP. A Comprehensive Review on Floating Drug Delivery System, Int J Res Pharm Biomed Sci. 2011; 2(2):428-41. https://doi.org/10.7439/ijbr.v2i6.118
28. Gadhve MV, Lende LK, Tajane TS and Gaikwad DD. Formulation and Development of Bilayer Floating Tablet of Nifedipine using surface solid dispersion technique, Int J Adv Pharm. 2016; 5(5):117
29.Reddy R.S, Ramachandra C.T, Hiregoudar S, Nidoni U.K, Kammar M, and Ram J. influence of processing conditions on functional and reconstitution properties of milk powder made from Osmanabadi goat milk by spray drying, Small Ruminant Res. 2014; 119:130-137. https://doi.org/10.1016/j.smallrumres.2014.01.013
30. Chaudhary A, Renthlei L, Dewan M, Ahmed R, Barakoti H, and Dey B.k. floating drug delivery system: an outlook, Journal of applied pharmaceutical research. 2019; 7(3):1-8. https://doi.org/10.18231/j.joapr.2019.003
31. Moursy N.M, Afifi N.N, Ghorab D.M, ElSaharty Y. Formulation and evaluation of sustained release floating capsules of Nicardipine hydrochloride, Pharmazie. 2003; 58:38-43.
32. Pakhale NV, Gondkar SB, Saudagar RB. Effervescent Floating Drug Delivery System: A Review, Journal of Drug Delivery and Therapeutics. 2019; 9(3-s):836-838. https://doi.org/10.22270/jddt.v9i4-A.3490
33. Sonar G. S. Bioadhesive-floating matrix tablet of salbutamol sulphate using response surface methodology: optimization and in vitro evaluation, J Pharm Res. 2009; 2(5):908-914.
34. Sharma V, Rathore D, Kumar A. Floating drug delivery system: a review, International Journal of Medical and Biomedical Studies. 2020; 4(8):23-30 https://doi.org/10.32553/ijmbs.v4i8.1333
2. Pattanaya D, Mondal K, Hooain M, Das S, Ali M. A review on floating drug delivery systems in present scenario, Int J Pharm Res Health Sci. 2018; 6(5):2755-62.
3. Yadav S, Yadav S, Mishra A, Kumar A and Kushwaha SS, Floating Drug Delivery System an Aid to Enhance Dissolution Profile of Gastric, Journal of Drug Delivery & Therapeutics. 2021; 11(6):286-296 https://doi.org/10.22270/jddt.v11i6.5153
4. Sopyan, I., & Wahyuningrum, R. A review: Floating drug delivery system as a tool to improve dissolution rate in gastric, International Journal of Applied Pharmaceutics, 2020:51-54. https://doi.org/10.22159/ijap.2020v12i4.38415
5.Niharika M.G, Krishnamoorthy K, Akaala M. overview on floating drug delivery system, International journal of applied pharmaceutics.2018; 10(6):65-71 https://doi.org/10.22159/ijap.2018v10i6.28274
6. Khairnar VS, Patil ST, Pawar SP. Effervescent Drug Delivery System, International Journal of Pharma and Chemical Research. 2017; 3(2):260-266.
7. Wang L, Liu X. Sustained Release Technology and Its Application in Environmental Remediation: A Review, Environmental Research and Public Health. 2019; 16(12):2153. https://doi.org/10.3390/ijerph16122153
8. Datir SK, Patil PB, Saudagar RB. Floating type drug delivery system: a review, J Drug Deliv Ther. 2019; 9(2):428-32. https://doi.org/10.22270/jddt.v9i2.2492
9. Patil P, Baviskar P, Saudagar RB. Floating Drug Delivery System: A comprehensive review, J Drug Deliv Ther. 2019; 9(3-s):839-46. https://doi.org/10.22270/jddt.v9i4-s.3384
10.Farooq SM, Sunaina S, Rao M, Venkatesh P, Hepcykalarani D, Preama R. Floating Drug Delivery Systems: An updated Review, Asian Journal of Pharmaceutical Research. 2020 Mar 9; 10(1):39-47. https://doi.org/10.5958/2231-5691.2020.00009.X
11. Tripathi J, Thapa P, Maharjan R and Jeong SH. Current State and Future Perspectives on Gastroretentive Drug Delivery Systems, Pharmaceutics. 2019; 11(4):122. https://doi.org/10.3390/pharmaceutics11040193
12. Kamalakkannan V, Pyratchikody A, Viswanadhan VP,"Enhancement of Drugs bioavailability by Floating Drug Delivery System-A Review.''Int. J. Drug Delivery.2011; 3(4): 558-570.
13. Zubedi S.S, Mohammed S . floating tablet and its polymers, Journal of Drug Delivery & Therapeutics. 2018; 8(5-s):16-24 https://doi.org/10.22270/jddt.v8i5-s.1928
14. Kumar G. Natural Polymers in the Development of Floating Drug Delivery Systems: A Review, Int. J. Pharm. Life Sci, 2013; 2(4):165-178. https://doi.org/10.3329/ijpls.v2i4.17116
15. Singh A, kumar. Role of Natural Polymers Used In Floating Drug Delivery System Floating Drug Delivery System. J. Pharm. Sci. Innov, June. 2012; 1:11-15.
16. Milanovic J., Manojlovic V., Levic S., Rajic N., Nedovic V. & Bugarski B. Microencapsulation of Flavors in Carnauba Wax. Sensors, 2010; 10:901-912. https://doi.org/10.3390/s100100901
17. Thakur S, Ramaya k, Saha D K, Raj k. Floating Drug Delivery System,Journal of Drug Delivery &Therapeutics. 2021; 11(3-s):125-130 https://doi.org/10.22270/jddt.v11i3-S.4828
18. Roshani K, Panda P, Vishwakarma DK, Verma NK. A brief review on bilayer floating A brief review on bilayer floating tablet, International Journal of Advances in Pharmaceutics. 2017; 6(3):70-78.
19. Rathod H, Patel V and Modasia M. Floating drug delivery system: Innovative Approach of Gastroretention, Int J Pharm Sciences Review and Research. 2010; 4(3):183-191.
20. Kaushik AY, Tiwari A K and Gaur A. Role of Excipients and polymeric advancements in preparation of floating drug delivery systems, Int J Pharm Investig. 2015; 5(1):1-12. https://doi.org/10.4103/2230-973X.147219
21. Pakhale NV, Gondkar SB, Saudagar RB, Effervescent Floating Drug Delivery System: A Review, Journal of Drug Delivery and Therapeutics. 2019; 9(3-s):836-838. https://doi.org/10.22270/jddt.v9i4-A.3490
22. Padhan et al. Floating Oral In-situ Gel, A Comprehensive Approach of Gastroretentive Drug Delivery System: A Review, IJPSR. 2019; 10(9):4026-4039.
23. Kumari B. Recent Development in Floating Drug Delivery System: A Review, Asian Journal of Pharmacy and Pharmacology. 2018; 4(2):131-139. https://doi.org/10.31024/ajpp.2018.4.2.6
24. Jaimini R, Gupta MK, Sharma V. A Review on Formulation and Evaluation of Gastroretentive Floating Tablet of Nifedipin, Journal of Drug Delivery and Therapeutics. 2019 Jul 15; 9(4):651-6.
25. Nur A.O, Zhang J.S. Captopril floating and/or bioadhesive tablets: design and release kinetics.Drug Dev Ind Pharm. 2000; 26:965-969. https://doi.org/10.1081/DDC-100101323
26. Sopyan I, Sriwidodo, Wahyuningrum R, Norisca Aliza P. A review: Floating drug delivery system as a tool to improve dissolution rate in gastric, Int J Appl Pharm. 2020; 12(4):51-4. https://doi.org/10.22159/ijap.2020v12i4.38415
27. Sharma N, Agarwal D, Gupta MK and Khinchi MP. A Comprehensive Review on Floating Drug Delivery System, Int J Res Pharm Biomed Sci. 2011; 2(2):428-41. https://doi.org/10.7439/ijbr.v2i6.118
28. Gadhve MV, Lende LK, Tajane TS and Gaikwad DD. Formulation and Development of Bilayer Floating Tablet of Nifedipine using surface solid dispersion technique, Int J Adv Pharm. 2016; 5(5):117
29.Reddy R.S, Ramachandra C.T, Hiregoudar S, Nidoni U.K, Kammar M, and Ram J. influence of processing conditions on functional and reconstitution properties of milk powder made from Osmanabadi goat milk by spray drying, Small Ruminant Res. 2014; 119:130-137. https://doi.org/10.1016/j.smallrumres.2014.01.013
30. Chaudhary A, Renthlei L, Dewan M, Ahmed R, Barakoti H, and Dey B.k. floating drug delivery system: an outlook, Journal of applied pharmaceutical research. 2019; 7(3):1-8. https://doi.org/10.18231/j.joapr.2019.003
31. Moursy N.M, Afifi N.N, Ghorab D.M, ElSaharty Y. Formulation and evaluation of sustained release floating capsules of Nicardipine hydrochloride, Pharmazie. 2003; 58:38-43.
32. Pakhale NV, Gondkar SB, Saudagar RB. Effervescent Floating Drug Delivery System: A Review, Journal of Drug Delivery and Therapeutics. 2019; 9(3-s):836-838. https://doi.org/10.22270/jddt.v9i4-A.3490
33. Sonar G. S. Bioadhesive-floating matrix tablet of salbutamol sulphate using response surface methodology: optimization and in vitro evaluation, J Pharm Res. 2009; 2(5):908-914.
34. Sharma V, Rathore D, Kumar A. Floating drug delivery system: a review, International Journal of Medical and Biomedical Studies. 2020; 4(8):23-30 https://doi.org/10.32553/ijmbs.v4i8.1333
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Chaudhary S, Dua J, Prasad D. Recent Development in Floating Drug Delivery System: An Overview. JDDT [Internet]. 15Jan.2022 [cited 2Oct.2023];12(1):185-93. Available from: https://jddtonline.info/index.php/jddt/article/view/5171
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