IN-VITRO AND IN-VIVO CHARACTERIZATION OF MOUTH DISSOLVING TABLET: AN UPDATED REVIEW
Abstract
Mouth dissolving tablets (MDTs) has extended much attention as a preferred alternative to conventional oral dosage form. It provides an advantage particularly for pediatric and geriatric populations who have difficulty in swallowing conventional tablets and capsules. MDTs have the unique property of rapidly disintegrating and/ or dissolving or releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. The current review describes the ideal characteristics, significance, limitations and mainly lays emphasis on the in-vitro and in-vivo characterization of MDT.
Keywords: Mouth dissolving tablets, disintegration, in-vivo and in-vitro evaluation, dysphagia.
DOI
https://doi.org/10.22270/jddt.v3i3.494Published


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