The Relevance of Defined Daily Dose concept in Drug Utilisation Research: A Review
Abstract
According to World Health Organisation (WHO), drug utilisation is defined as the marketing, distribution, prescription and the use of drugs in society with special focus on resulting medical, social and economic consequences and it has turned into a powerful scientific tool for ensuring the rational and cost-effective use of drugs. A standard method is required to identify and aggregate drug data. This manuscript provides an overview of the WHO Anatomical Therapeutic Chemical (ATC) classification and the associated measure, Defined Daily Dose (DDD), as a methodology for evaluating drug utilisation.
Keywords: Drug utilisation research, Anatomical Therapeutic Chemical classification system, Defined Daily Dose, Rational drug use.
Keywords:
Drug utilisation research, Anatomical Therapeutic Chemical classification system, Defined Daily Dose, Rational drug useDOI
https://doi.org/10.22270/jddt.v11i4-S.4897References
Trute I, A Review of Drug Utilization Studies and Methodologies, Jordan Journal of Pharmaceutical Sciences, 2008; 1(2):91-103.
Teng L et al., Review of the use of defined daily dose concept in drug utilisation research in China, Pharmacoepidemiology and Drug Safety, 2012; 21(10):1118-1124. https://doi.org/10.1002/pds.3240
Atif M, Scahill S, Muhammad Azeem, Muhammad Rehan Sarwar, Zaheer-Ud-Din Babar, Drug utilization patterns in the global context: a systematic review, Health Policy and Technology, 2017; 6(4):457-470. https://doi.org/10.1016/j.hlpt.2017.11.001
The Selection of Essential Drugs: Report of a WHO Expert Committee. Technical Report Series no.615. Geneva: World Health Organization, 1977.
Wettermark B et al., Studies of Drug Utilization, 373-410. https://doi.org/10.1002/9781118949740.ch1
Wertheimer AI, Santella TM, Problems Using the Defined Daily Dose (DDD) as a Statistical Basis for Drug Pricing and Reimbursement, 1-15.
Sketris et al., The Use of the World Health Organisation Anatomical Therapeutic Chemical/Defined Daily Dose Methodology in Canada, Drug Information Journal, 2004; 38(1):15-27. https://doi.org/10.1177/009286150403800104
Merlo J, Wessling A, Melander A, Comparison of dose standard units for drug utilisation studies, Eur J Clin Pharmacol, 1996; 50(1-2):27–30. https://doi.org/10.1007/s002280050064
Gama H, Drug Utilization Studies, Arquivos de medicina, 2008; 22(2/3):69-74.
WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index. 2020 Available from https://www.whocc.no/atc_ddd_index/
Bachhav SS, Kshirsagar NA, Systematic review of drug utilization studies & the use of the drug classification system in the WHO-SEARO Region, Indian J Med Res, 2015; 142(2):120-129. https://doi.org/10.4103/0971-5916.164223
Kumar A et.al., Point prevalence study of use and consumption of antibiotics by using Anatomical and Therapeutic Chemical Classification and Defined Daily Dose Methodology in Tertiary Care Hospital, Indian Journal of Pharmacy Practice, 2020; 13(2):151-155. https://doi.org/10.5530/ijopp.13.2.23
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