A Review on Deprescribing in Elderly

  • Christy Babu Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India https://orcid.org/0000-0002-2224-6349
  • Lincy George Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India
  • K. Krishnakumar Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

Abstract

Deprescribing can be defined as the process of stopping a medication or reducing its dose to reduce adverse effects and improve health outcomes. Elderly people with co morbidities usually have a risk of adverse drug events and these events can only be treated by medicines. Despite the benefits offered by these medicines, older patients are at a high risk of harm caused by these medications. The use of multiple medications for treating the comorbidities may also leads to severe health problems. Deprescribing help to reduce the risk related to inappropriate medicines. Deprescribing is usually a patient centered process which helps to withdraw drugs which are harmful to be prescribed to older patients. Several explicit and implicit tools have been developed internationally to identify these inappropriate medications. Deprescribing of inappropriate medicines would help to reduces drug-related harm and improves the quality of life of older adults.


Keywords: Deprescribing, polypharmacy, older adults

Keywords: Deprescribing, polypharmacy, older adults

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Author Biographies

Christy Babu, Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

Lincy George, Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

K. Krishnakumar, Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

Department of Pharmacy Practice St James’ College of Pharmaceutical Sciences, St James’ Hospital Trust Pharmaceutical Research Centre (DSIR recognized), Chalakudy, Kerala, India

References

1. Le Bosquet K, Barnett, N Minshull J, Deprescribing: Practical ways to support person-centered, evidence-based deprescribing, Pharmacy, 2019; 7(3):129-139 https://doi.org/10.3390/pharmacy7030129
2. Woodford HJ, Fisher J, New horizons in deprescribing for older people, Age and ageing, 2019; 48(6):768-775. https://doi.org/10.1093/ageing/afz109
3. Potter K, Flicker L, Page A, Etherton-Beer C, Deprescribing in frail older people: a randomized contolled trail, PloS one, 2016; 11(3):149-155 https://doi.org/10.1371/journal.pone.0149984
4. HilmerSN, GnjidicD, The effects of polypharmacy in older adults, Clinical Pharmacology & Therapeutics, 2009; 85(1):86-8 https://doi.org/10.1038/clpt.2008.224
5. Le Couteur D, Banks E, Gnjidic D, McLzchlan A, Deprescribing, Australian prescriber, 2011; 34(6):182-185 https://doi.org/10.18773/austprescr.2011.095
6. Liacos M, Page AT, Etherton-Beer C, Deprescribing in older people,Australian prescriber, 2020; 43(4):114-120 https://doi.org/10.18773/austprescr.2020.033
7. Curtin D, Gallagher P,O' Mahony D, Deprescribing in older people approaching end-of-life: development and validation of STOPP Frail version 2,Age and ageing, 2021; 50(2):465-471. https://doi.org/10.1093/ageing/afaa159
8. Planton J, Edlund B, Strategies of reducing polypharmacy in older adults, Journal of gerontological nursing, 2019; 36(1):8-12. https://doi.org/10.3928/00989134-20091204-03
9. Reeve E, To J, Hendrix I, Shakib S, Roberts MS, Wiese MD, Patient barriers to and enablers of deprescribing: a systematic review, Drugs & ageing, 2013;30(10):793-807. https://doi.org/10.1007/s40266-013-0106-8
10. Salahudeen MS, Deprescribing medications in older people: a narrative review, Drugs of Today, 2018; 54(8):3489-3498. https://doi.org/10.1358/dot.2018.54.8.2856495
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Babu C, George L, Krishnakumar K. A Review on Deprescribing in Elderly. JDDT [Internet]. 15Jul.2021 [cited 28Mar.2024];11(4):136-7. Available from: https://jddtonline.info/index.php/jddt/article/view/4871