Synthesis of 1,2 Disubstituted Benzo 1,3-Diazole Derivatives and Evaluation of Their In-vitro Antifungal Activities

  • Sunbee Prakash Institute of pharmacy, Shri Jagdish Prasad Jhabramal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India
  • Rakesh Kumar Jat Institute of pharmacy, Shri Jagdish Prasad Jhabramal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India

Abstract

The present research work was meant to blend some Mannich bases of benzo1,3-diazole dervivatives and was explored for their organic exercises. The recently incorporated mixes have been portrayed by their explanatory and unearthly (IR, 1HNMR, Mass spectra) properties. Every one of the mixes have been screened for their antifungal exercises by standard strategies. BZ2, BZ3 and BZ6 displayed Promising antifungal activity.


Keywords: Benzo1,3-diazole, o-phenylenediamine, urea, benzamide, Hydroxylamine, Antifungal activity.

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Author Biographies

Sunbee Prakash, Institute of pharmacy, Shri Jagdish Prasad Jhabramal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India

Institute of pharmacy, Shri Jagdish Prasad Jhabramal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India

Rakesh Kumar Jat, Institute of pharmacy, Shri Jagdish Prasad Jhabramal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India

Institute of pharmacy, Shri Jagdish Prasad Jhabramal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India

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1.
Prakash S, Jat RK. Synthesis of 1,2 Disubstituted Benzo 1,3-Diazole Derivatives and Evaluation of Their In-vitro Antifungal Activities. JDDT [Internet]. 11Nov.2019 [cited 14Jun.2021];9(4-s):1001-6. Available from: https://jddtonline.info/index.php/jddt/article/view/3710