Fast Dissolving Tablets: Better Option for Pediatrics and Geriatrics
Abstract
Fast dissolving tablets are getting more importance as it has advantages over conventional tablets and liquid dosage form. Problems like dysphasia, swallowing, shocking are not seen with fast dissolving tablets. As it mixes rapidly as comes in contact with saliva. Direct compression method is the most common, simple, less step and low cost methods. Fast dissolving tablets preparation i.e based on many techniques like spray drying, sublimation, melt granulation, lyophilization, mass extrusion etc and by addition of superdisintegrant. In the review paper we are going to discuss regarding fast dissolving tablets, their preparation and evaluation methods.
Keywords: Fast dissolving tablets, Direct compression, first pass metabolism
DOI
https://doi.org/10.22270/jddt.v9i4-A.3689References
Cheng R, Guo X, Burusid B, Couch R.A review of fast dissolving tablets.Pharm Tech, (North America).June,2000;Vol 1,pg-52-58.
Bi Y, Sunada H,Yonezawa Y, Dayo K,Otsuka A, Iida K.Preparation and evaluation of compressed tablet rapidly disintegrating in oral cavity.Chem Pharm Bull(Tokyo)1996; Vol 1, 44:2121-2127.
Bradoo, R., Fast Dissolving Drug Delivery Systems, JAMA India, 2001, Vol 2, 4(10), 27-31.
Argade GD, Magar DD, Saudagar RB. Review article on solid dispersion as solubility enhancement technique for poorly water soluble drugs. J Adv Pharm Edu Res 2013; Vol 3, 3:427-39.
Singh J, Walia M, Harikumar SL. Formulation and evaluation of fast dissolving tablets of rosuvastatin. J Drug Delivery Ther 2013; Vol 4, 3:148-55.
Dixit AK, Singh RP, Singh Stuti. Formulation and evaluation of solid dispersion of amlodipine besylate. Int J Res Pharm Biomed Sci 2015; Vol 16, 3:960-6.
Chauhan R, Virmani S, Suman P. Quantitative method development and validation of sulfasalazine in tablet dosage form by uv-spectroscopy. Int J Pharm Sci Rev Res 2015; Vol 9, 32:120-9.
KV, Raj GB, Ravishanker D, Kumar CA. Preparation and evaluation of montelukast oral dispersible tablets by direct compression method. Int Res J Pharm 2014; 7(7):315-8.
Deshmukh VN. Mouth dissolving drug delivery system: a review. Int J Pharm Tech Res 2016; Vol 4,4:412-21.
Leunar C, Dreessan J. Improving drug solubility for oral delivary using solid dispersion. Eur J Pharm Biopharm 2014; 3(50):47-60.
Yang D, Kulkarni R, Behme RJ, Kotiyan PN. Effect of the melt granulation technique on the dissolution characteristics of griseofulvin. Int J Pharm 2015;Vol 3,329:72-80.
Khan AB, Tripuraneni A. Fast dissolving tablets–a novel approach in drug delivery. Rguhs J Pharm Sci 2014; 10(1):7-16
Yarwood R, Kearnery P, Thompson A. Process for preparing solid pharmaceutical dosage form. US Patent 1998.Vol 2, 5,738,875.
Lafon L. Galenic form for oral administration and its method of preparation by lyophilization of an oil-in-water emulsion. US Patent 1986; 91(4):616,047.
Kaushik D, Dureja H, Saini TR. Orally disintegrating tablets: An overview of melt-in mouth tablet technologies and techniques. Tablets Capsules 2004; Vol 3, 2:30-6.
Argade GD, Magar DD, Saudagar RB. Review article on solid dispersion as solubility enhancement technique for poorly water soluble drugs. J Adv Pharm Edu Res 2013; 3:427-39.
Heinemann H and Rothe W,Preparation of porous Tablets . US Patent 1976; Volume 4, Issue 3, 1712-1728 No 3885026.
Varun RJ, Venkateshwarlu L, Srikanth L. Combinational products: a regulatory review. Int J Pharm Sci Rev Res 2015; 5(5):41-51.
Yang D, Kulkarni R, Behme RJ, Kotiyan PN. Effect of the melt granulation technique on the dissolution characteristics of griseofulvin. Int J Pharm 2015; 9(329):72-80.
Published
Abstract Display: 599 
PDF Downloads: 547 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.