SKELETAL DRUG DELIVERY SYSTEM: A REVIEW

  • Mousumi Kar College of Pharmacy, IPS Academy, Indore
  • Sourabh Singh College of Pharmacy, IPS Academy, Indore
  • Sourabh Singh College of Pharmacy, IPS Academy, Indore
  • Dinesh K Jain College of Pharmacy, IPS Academy, Indore
  • Dinesh K Jain College of Pharmacy, IPS Academy, Indore

Abstract

Drug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Skeletal drug delivery systems (SDDS) are used to deliver the drug directly to skeletal tissue through various conventional and novel approaches, thereby improving the therapeutic effectiveness of drugs in bone diseases. It may involve scientific site-targeting within the body, or it might involve facilitating systemic pharmacokinetics; in any case, it is typically concerned with both quantity and duration of drug presence.

Ranging from used of poultice and now with the advent of self setting cements, nanoparticles, liposomes etc for targeting the drug to the poorly perfused body organs, the development of delivery systems to bones/ skeletal system have come a long way. The present work reviews the delivery systems that are prevalent and is dedicated towards a rationale selection of the drugs and dosage forms for skeletal diseases.

Downloads

Download data is not yet available.

Author Biography

Mousumi Kar, College of Pharmacy, IPS Academy, Indore
Professor, College of Pharmacy, IPS Academy, Indore
Statistics
190 Views | 352 Downloads
How to Cite
1.
Kar M, Singh S, Singh S, Jain D, Jain D. SKELETAL DRUG DELIVERY SYSTEM: A REVIEW. JDDT [Internet]. 15May2014 [cited 4Dec.2021];4(3):60-8. Available from: https://jddtonline.info/index.php/jddt/article/view/836