Advancement in Green nano-formulation for management of Gynaecological disorders: Emerging trends and Therapeutic insights
Abstract
Objective: Considering environmentally friendly methods of synthesis, greater efficacy, and lower systemic toxicity compared to conventional therapies, this paper provides a critical review of recent advances in green nano-formulation approaches in treating gynaecological disorders.
Sources of Data: Comprehensive narrative literature as well as reliable pharmaceutical and biomedical resources was searched using PubMed, Scopus, Google Scholar and Science Direct. Studies related to green nanotechnology and gynaecological therapies, dated from 2010 to 2026, were prioritized.
Summary of Contents: Low drug solubility, potential for systemic side effects, and limited ability for target-specific administration have provided challenges to the successful therapeutic intervention of nano-formulations in gynaecological conditions such as PCOS, endometriosis, cervical cancer, and vaginal infections. Green nano-formulations that are produced through the use of biopolymers, plant extracts, and environmentally friendly techniques have emerged as alternative nanocarrier candidates. They consist of lipid-based systems, nano-emulsions, and nanoparticles created using environmentally friendly processes. The review demonstrates how the creation of nanoparticles by phytochemicals can positively influence drug delivery and drug efficacy. The clinical performance of the discussed systems is addressed based on certain parameters, including particle size, surface charge, encapsulation efficiency, and biocompatibility.
Conclusion: The integration of green chemistry and nanotechnology can be considered as an innovative strategy for treating diseases associated with gynaecology. The usage of nano-formulations is promising in terms of safety, efficiency, and patients' compliance, although additional studies are needed to ensure its successful implementation in medical practice.
Keywords: Green nanotechnology, nano-formulation, gynaecological disorders, drug delivery, bioavailability, sustainability
Keywords:
Greennanotechnology, Nano-formulation, Gynaecological disorders, Drug delivery, Bioavailability, SustainabilityDOI
https://doi.org/10.22270/jddt.v16i5.7738References
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Copyright (c) 2026 Pyari Payal Beura , Sulagna Dash Mohapatra , Adyasha Dash , Rashmirekha Satpathy , Sanjay Kumar Raul
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