Applicability of Katan (Flaxseed) according to Unani Perspective and Scientific Insight: A comprehensive Review
Abstract
This review comprehensively examines Linum usitatissimum (flaxseed) through the dual lenses of classical Unani medicine and contemporary biomedical research. It highlights flaxseed’s extensive therapeutic potential, including antioxidant, anti-inflammatory, hepatoprotective, hypolipidemic, antidiabetic, neuroprotective, bone-strengthening, anticancer, wound-healing, immunomodulatory, and gut microbiota-modulating effects. The integration of traditional Unani concepts such as Mizāj (temperament) and Akhlāṭ (humors) with modern pharmacological findings underscores the convergence of ancient humoral theory and molecular science. Key bioactive constituents—lignans, α-linolenic acid, mucilage polysaccharides, bioactive peptides, phenolic acids, and phytosterols—mediate these effects through synergistic mechanisms involving oxidative stress reduction, inflammation modulation, lipid metabolism regulation, and immune support. Clinical evidence supports flaxseed’s safety and efficacy within recommended doses, though variability in outcomes and limited large-scale trials highlight the need for further rigorous research. Emphasizing integrative approaches that incorporate Unani diagnostic frameworks, this review positions flaxseed as a valuable model for evidence-based integrative medicine and nutraceutical development.
Keywords: Flexseed, Katan, Unani Medicine, Linum usitatissimum, Pharmacology
Keywords:
• Bioavailability, • Unani medicine, , Flaxseed, Pharmacology, katanDOI
https://doi.org/10.22270/jddt.v15i12.7460References
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