A Review of Darchini (Cinnamomum zeylanicum) in Unani Medicine with Therapeutic Benefits and other Pharmacological potential
Abstract
Darchini (Cinnamomum zeylanicum) is a bark of a cinnamon plant that belongs to the Lauraceae family. Cinnamon is a rich tasting and aromatic spice used by different cultures worldwide. Recently, many phytochemicals were discovered and obtained from Darchini. Numerous experimental research using these phytochemical components have established several therapeutic actions. In addition, it possesses useful medicinal properties and is considered a remedy for indigestion, flatulency, depletion of innate heat, respiratory diseases, diabetes, cardiovascular diseases, and neurological disorders. A manual literature search of classical Unani manuscripts was carried out to acquire information on temperament (Mizaj), pharmacological activities and medicinal applications of Darchini. In addition, all accessible material on phytochemical, physiochemical and pharmacological studies have been collected using an extensive review of internet sources such PubMed, Google Scholar and Science Direct. The aim of this review article is to further highlight the discovered pharmacological effect and medicinal values of Cinnamomum zeylanicum as per the Unani literature as well as scientific research. Based on scientific studies regarding its phytochemical components, it is beneficial for various ailments. Darchini also has a beneficial effect on some gynaecological disorders such as amenorrhoea, dysmenorrhoea, leucorrhoea, menorrhagia, prolapse, and vaginosis. However, there is need to conduct experimental and clinical study to validate their effectiveness and safety in humans.
Keywords: Cinnamomum zeylanicum, Darchini, Gynaecological disorders Phytochemicals, Unani system of medicine
Keywords:
Cinnamomum zeylanicum, Darchini, Gynaecological disorders, Phytochemicals, Unani system of medicineDOI
https://doi.org/10.22270/jddt.v14i6.6645References
Kritikar KR, Basu B. D. Indian Medicinal Plants 2nd edition vol. III international book publisher and distributors Dehradun. 2008. 2149-2150 p.
Rajagopalan pallavi kawatra and rathai. cinnamon: mystic powers of a minute ingredient. Pharmacogn res 2015 june; 7 (suppl 1) ). 2015;1-6(suppl 1). https://doi.org/10.4103/0974-8490.157990 PMid:26109781 PMCid:PMC4466762
SP PSAV. medicinal plant cultivation a scientific approach publisher agrobios jodhpur india. 2008. 367-70 p.
Prajapati N D, Purohit S S, Sharma A K kumar tarun. a hand book of medicinal plants a complete source book, publisher agrobios jodhpur india. 2009. 144 p.
Khare CP. Indian Medicinal Plants An Illustrated Dictionary. Berlin: Heidelberg Springer; 2007. 151. https://doi.org/10.1007/978-0-387-70638-2 PMCid:PMC2705749
Ali M. Text Book of Phamacognosy vol.1, CBS publisher and distributer New Delhi. 2009. 441-445 p.
Ainul-Hayat HM. (Urdu translation by Zillur Rahman S). Aligarh: Ibn Sina Academy; 2007. 182-183, 256-264 p.
Khan MA. Muhit-I Azam. (Urdu translation by CCRUM). Vol.II Published by CCRUM;New Delhi. 2013. 529-533 p.
The Unani Pharmacopoeia of India, Vol.1 Part 1 New Delhi: Ministry of Health and Family welfare, Gov. of India; Dept. of AYUSH. 2007. 26-27 p.
(www.plants.usda.gov,United State Department of agriculture, Natural Resources Conservation Service.).
WC. E. Trease and Evans Pharmacognosy. 16thedition.London, New York: Elsevier; 2009. 283-285. p.
The Wealth of India, Raw Materials, Publications & Information Directorate, Vol. III. New Delhi: 1992. 582-587. 1992. 582-587 p.
Kokate C K, Purohit A P GSB. pharmacognosy, vol. I, 47th edition, published by niraliprakashan, pune. 2012. 1.46-1.47.
HMA K. MuheeteAzam. Vol 2. Urdu translation by CCRUM. New Delhi: CCRUM. 2013. 531-532 p.
Sina I. Al Qanoon fit Tib. (Translated by Ghulam HasnainKanturi). Vol.II. New Delhi: Aejaz publishing house; 2010: 314-315.
Pathak R, Sharma H, A review on medicinal uses of Cinnamomum verum (Cinnamon), Journal of Drug Delivery and Therapeutics. 2011;11(6-S):161-166 https://doi.org/10.22270/jddt.v11i6-S.5145
Nonaka G-I, Morimoto S NI. Tannins and related compounds. Part 13. Isolation and structures of trimeric, tetrameric, and pentameric proanthicyanidins from cinnamon. J Chem Soc Perkin Trans 1. 1983;2139-2145. https://doi.org/10.1039/p19830002139
The Unani Pharmacopoeia of India, Vol.1 Part 1 AYUSH Publisher and Distributor. 2007. 26 p.
Pasupuleti Visweswara Rao, Siew Hua Gan C. A Multifaceted Medicinal Plant, Evid Based ; doi.org/10.1155/2014/642942. Complement Altern Med. 2014; https://doi.org/10.1155/2014/642942 PMid:24817901 PMCid:PMC4003790
Nabavi SF, Di Lorenzo A Izadi M, Sobarzo-Sánchez E, Daglia M NS. Antibacterial Effects of Cinnamon: From Farm to Food, Cosmetic and Pharmaceutical Industries. Nutrients. 2015;7(9):7729-48. https://doi.org/10.3390/nu7095359 PMid:26378575 PMCid:PMC4586554
Ghani N. KhazainulAdvia. New Delhi: IdaraKitab-us-Shifa. 682-684. p.
IntakiDaud. TazkirahUlilAlbab Vol. 1. CCRUM New Delhi. 2008. 278 p.
Duke JA, Godwin MJB, du Cellier J D. Handbook of Medicinal Herbs; second edition, crcpublisher. 2006. 197 p.
AS M. Kitabul Miaát al maroof Miaát-e-Maseehi. Vol. 1. (Urdu Translation by CCRUM). New Delhi: CCRUM, Ministry of Health & Family Welfare, Government of India; 211-212, 228, 276-293. p.
I B. Al-Jamiul Mufradat al-Advia wal-Aghzia, Vol II. New Delhi: CCRUM; Ministry of Health and Family welfare. 2000. 170-73 p.
Hasan T mumeneen. hasani mohammad. publisher and distributor. Khan HMA. MuheeteAzam. Vol 2. Urdu translation by CCRUM. New Delhi: CCRUM; 2013. 531-532 p.
NA T. Taj-ul-Mufradat (Khwas-ul-Advia). New Delhi: Idara Kitab-us-Shifa, Koocha Chelan, Darya Ganj; 2010. 347-349 p.
28. Khan MM. Tohfatul Momeneen. Lucknow: Matba Noval Kishore. 1846. 113-14 p.
Multani HC. Hind-o-Pak ki jadi-bootiyan aur unke fawaed. Part 6th. Lahore: Abu Bakr Siddique, Maktaba Daniyal; YNM: 561-563.
Maseehi AAIQ. Kitabul Umdah fil Jarahat. Volume-1, maqala 11th, fasl 4th. (Urdu translation). New Delhi: CCRUM, Ministry of Health & Family Welfare, Government of India; Vol. 1. 261 p.
Ali SS. Unani Advia-e-Mufrada. New Delhi: Qaumi Council Baraye Farogh Urdu Zaban. 2004. 153-154 p.
Shahabuddin M. Description of Darchini (Cinnamomum Zeylanicum) in Unani Medicine: a Review. World J Pharm Res. 2017;6(5):1311-29. https://doi.org/10.20959/wjpr20175-8424
Asad M. Antiulcer Effect of Cinnamomum zeylanicumBark in Rats. ResearchJournalofBiologicalSciences. 2014;9(5):182-9.
Ali SM and HH. Hepatoprotective effect of Cinnamon extracts against carbon tetrachloride induced oxidative stress and liver injury in rats. Biol Res. 2009;42:93-8. PMid:19621136 https://doi.org/10.4067/S0716-97602009000100009
Jian Zhen Ou E al. Potential of in vivo real-time gastric gas profiling: a pilot evaluation of heat-stress and modulating dietary cinnamon effect in an animal model. Sci Rep. 2016; 6: 33387. 2016; https://doi.org/10.1038/srep33387 PMid:27633400 PMCid:PMC5025890
Juan Jiang, Margo P. Emont, Heejin Jun, Xiaona Qiao, Jiling Liao, Dong-il Kim and JW. in Metabolism: Clinical and Experimental. Published online November doi:10.1016/j. metabol.2017.08.006. 2017;
Subash Babu P., Prabuseenivasan S. Ignacimuthu S. Cinnamaldehyde-a potential antidiabetic agent. Phytomedicine. 2007; 14:15-22. https://doi.org/10.1016/j.phymed.2006.11.005 PMid:17140783
Kannappan S., Jayaraman T., Rajasekar P., Ravichandtan M.K. ACV. Cinnamon bark extract improves glucose metabolism and lipid profile in the fructose-fed rat. Singapore Med J. 2006;47:858-863.
Shen Y., Fukushima M., Ito Y., Muraki E., Hosono T., Seki T. AT. Verification of antidiabetic effects of cinnamon (Cinnamomum zeylanicum) using insulin-uncontrolled type 1 diabetic rats and cultured adipocytes. Bio sci Biotec Biochem. 2010;74:2418-2425. https://doi.org/10.1271/bbb.100453 PMid:21150113
Mang B., Wolters M., Schmitt B., Kelb K., Lichtinghagen R., Stichtenoth D.O. HA. Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2. . Eur J Clin Invest. 2006;36:340-344. https://doi.org/10.1111/j.1365-2362.2006.01629.x PMid:16634838
Suppapitiporn S., Kanpaksi N. SS. The effect of cinnamon cassia powder in type 2 diabetes mellitus. J Med Assoc Thai. 2006;89(S):200-205.
Rajendra Kumar Swain, Bimlendu Chowdhury MER. Analgesic Activity of Hydro alcoholic Extract of Cinnamomum zeylanicum Bark in Albino Rats. Curr pharma Res. 2016;7(i):2003-9. https://doi.org/10.33786/JCPR.2016.v07i01.004
Mohammad Hossein Dashti- R, Mohammad Davud, Qane, Farzane Shefaie, Mohammadreza Nazemian Yazdu SMB. Comparative Effect of Cinnamon Essential Oil, Diclofenac and Morphine on Acute and Chronic Pain in Mice. Int J Med Lab. 2016;3(2):92-103.
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