Management of risk factors and pharmacological therapy in oral pemphigus vulgaris: A Case Report

Abstract

Introduction: The incidence of pemphigus vulgaris is rare. It often occurs in middle age and the elderly or in the 4^th to 5^th decades. Women experience it more often than men. Pemphigus vulgaris predominates in patients of Ashkenazi Jewish, Asian or Mediterranean descent. The etiology of pemphigus vulgaris remains unclear, but it can be triggered by several risk factors, such as drugs, radiation, surgery, and some foods. This case report aims to describe a case of oral pemphigus vulgaris caused by stress and food and its management. Case: a 45-year-old woman who was hospitalized at Dr. Hasan Sadikin hospital referred from Dermatology and Venerology department to Oral Medicine department with diagnosis pemphigus vulgaris. The risk factors were emotional stress and food preservated. Pharmacology therapy including steroids, anti-fungal, and vitamins. Discussion: The management of this patient was carried out by a multidisciplinary team, dermatologist collaborate with oral medicine specialist to support comprehensive therapy. Identification and controlling emotional stress and cessation of food which was suspected as the cause, were the important aspect as an addition to the given pharmacological therapy led to significant improvement of oral pemphigus vulgaris. Conclusion: Oral pemphigus vulgaris as a chronic autoimmune disease can be cured if the risk factors can be controlled and close monitoring of pharmacological therapy can be carried out by a team.

Keywords: pharmacology, risk factor, oral pemphigus vulgaris