Butea monosperma (Lam.) Taub: Review on its chemistry, morphology, ethnomedical uses, phytochemistry and pharmacological activities
Abstract
Plants have been employed for their therapeutic and aesthetic benefits since ancient times. Traditional herbal medicine is well-documented and practised in India. The goal of the current review is to provide current information on botany, morphology, ecological biodiversity, medicinal uses, phytochemistry, and pharmacological activity on various portions of Butea monosperma (Lam.) Taub because there haven't been many studies done on it (B. monosperma). Technical literature from electronic search engines like Springerlink, BioMed Central, PubMed, Scopus, ScienceDirect, Scielo, Medline, and Science domain was used to compile this review. Books, book chapters, dissertations, websites, and other scientific publications served as the source of the supplemental texts. B. monosperma, a member of the Fabaceae family, is found throughout the Indian Subcontinent and Southeast Asia, including in Bangladesh, Nepal, Sri Lanka, Myanmar, Thailand, Laos, Cambodia, Vietnam, Malaysia, and western Indonesia. It is also known as Flame of the Forest, Dhak, Palash, or Bastard teak. It is an herb that has long been used voluntarily in traditional Asian treatments. It has been used to treat a variety of illnesses, including diabetes, cancer, diarrhoea, dysentery, fever, and jaundice. Recent in vivo and in vitro research have shown that it has hepatoprotective, anti-cancer, anti-diabetic, anti-inflammatory, anti-asthmatic, anti-oxidant, anti-convulsant, and anti-microbial effects. Many phytochemicals, primarily flavonoids, lactones, diterpenoids, diterpene glycosides, and phytosterols, are present in the plant's aerial portion. Bark produces a red fluid called "Butea gum" or "Bengal kino" that is produced. This complementary medical approach is becoming more and more well-known worldwide. Isolating the active components, testing them biologically, understanding their molecular mechanisms, mounting an experimental defence, and getting B. monosperma's medicinal usage approved are all necessary. The information gathered will be required to identify up study protocol for modern medications and Ayurveda formulation extension in luxurious and remedial a number of illnesses. To further validate the claims on humans, clinical trials for the stated preclinical investigations should be started right away.
Keywords: Butea monosperma, Fabaceae, Phytochemistry, Pharmacological activity, Ethno medical uses.
Keywords:
Butea monosperma, Fabaceae, Phytochemistry, Pharmacological activity, Ethno medical usesDOI
https://doi.org/10.22270/jddt.v13i4.5782References
World Health Organization. Containing Antimicrobial Resistance: Review of the Literature and Report of a WHO Workshop on the Development of a Global Strategy for the Containment of Antimicrobial Resistance. WHO/ CDS/CSR/DRS/99.2; 1999.
Ncube NS, Afolayan AJ, Okoh AI. Assessment techniques of antimicrobial properties of natural compounds of plant origin: current methods and future trends. African Journal of Biotechnology 2008; 7:1797-1806. https://doi.org/10.5897/AJB07.613
Aiyelaagbe O. Antibacterial activity of Jatropa multifida roots. Fitoterapia 2001; 72:544-546. https://doi.org/10.1016/S0367-326X(00)00291-4
Prince L, Prabakaran P. Antifungal activity of medicinal plants against plant pathogenic fungus Colletotrichum falcatum. Asian Journal of Plant Science Research 2011; 1:84-87.
WHO, Quality control methods for herbal materials, Updated edition of Quality control methods for medicinal plant materials, 1998.
Rai VM, Pai VR, Kedilaya PH, Hegde S. Preliminary phytochemical screening of members of Lamiaceae family: Leucas linifolia, Coleus aromaticus and Pogestemon patchouli. International Journal of Pharmaceutical Science Review and Research 2013; 21(1):131-137.
Lamaeswari G, Ananti T. Preliminary phytochemical screening and physicochemical characterization of Canna indica L. International Journal of Pharmaceutical Science Review and Research 2012; 14:76-79.
Karthikeyan A, Shanthi V, Nagasathaya A. Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica L. International Journal of Green Pharmaceae 2009; 3:78-80. https://doi.org/10.4103/0973-8258.49381
Kingston DG. Modern natural products drug discovery and its relevance to biodiversity conservation. Journal of Natural Product 2011; 74:496-511. https://doi.org/10.1021/np100550t
Narayana DBA, Katayar CK, Brindavanam NB. Original system: search, research or research. IDMA Bulletin 1998; 29:413-6.
Anonymous. The Wealth of India (Raw materials series), CSIR, New Delhi, Reprinted. 1988; 2B:341-346.
The Wealth of India-Raw Materials. CSIR, New Delhi, 1988; 2b:341-346.
Chopra RN, Chopra JC, Handa KL, Kapur LD. Indigenous drugs of India, 1958.
Chopra RN, Chopra IC. Indigenous drugs of India. Academic publishers, 1933.
Ambasta BP. The useful plants of India. CSIR, New Delhi, 1994, 1-91.
Nadkarni KM. Indian Materia Medica. 2002; 1:223-225.
Sequeira V, Bezkorowajnyj PG. Improved management of Butea monosperma (Lam.) Taub for lac production in India. Forest Ecology and Management 1998; 102(2-3):225-234. https://doi.org/10.1016/S0378-1127(97)00164-3
Jarald Edwin E, Jarald Edwin S. Colour Atlas of Medicinal Plants, CBS publishers and Distributers, New Delhi, 2006, 54.
Butea monosperma Germplasm Resources Information Network (GRIN). Agricultural Research Service (ARS), United States Department of Agriculture (USDA). Retrieved 2009-10-24.
Kirtikar KR, Basu BD. Indian Medicinal Plants, Edn 2, Vol-I, Lalit Mohan Basu Allahabad, India, 1935; 785-788.
Madhavi A. An overview of Butea monosperma (Flame of Forest). World Journal of Pharmacy and Pharmaceutical Sciences 2013; 3:307-319.
Wagner H, Geyer B, Fiebig M, Kiso Y, Hikino H. Isoputrin and butrin, the antihepatotoxic principles of Butea monosperma flowers1. Planta Medica 1986; 52(02):77-79. https://doi.org/10.1055/s-2007-969083
Acharyya S, Patra A, Bag PK. Evaluation of the antimicrobial activity of some medicinal plants against enteric bacteria with particular reference to multi-drug resistant Vibrio cholera. Tropical journal of pharmaceutical Research, 2009; 8(3):123-130. https://doi.org/10.4314/tjpr.v8i3.44538
Fageria D, Rao DV. A Review on Butea monosperma (Lam.) kuntze: A Great Therapeutic Valuable Leguminous Plant. The International Journal of Scientific and Research Publication 2015; 5: 1-9.
Sharma PV, Namarupajnanam, Chaukhambha V. Charak Samhita.Varanasi. Reprinted, 2011: 123
Dubey D, Rath S, Sahu MC, Debata NK, Padhy RN. Antimicrobials of plant origin against TB and other infections and Economics of plant drugs-Introspection, 2012.
Verma M, Shukla YN, Jain SP, Kumar S. Chemistry and biology of the Indian dhak tree Butea monosperma. Journal of Medicinal and aromatic plant sciences. 1998; 20:85-92.
Seshadri TR, Trikha RK. Proanthocyanidins from the bark & gum of Butea monosperma. Indian journal of chemistry. 1971; 9:1201.
Jhade D, Ahirwar D, Sharma NK, Jain R, Gupta S. Butea monosperma (Lam.) taubert: a review. Journal of Pharmacy research 2009; 2(7):1181-3.
Sumeet D. Relevance of medicinal herbs used in the traditional system of medicine. Farmavita. net. 2006.
Dwivedi S, Kaul S. Ethnomedicinal uses of some plant species by ethnic and rural peoples of Indore district of Madhya Pradesh, India Pharma Review. 2008; 6(2):239-45.
Kirtikar KR, Basu BD. Indian Medicinal Plants, Edn 2, Vol-I, Lalit Mohan Basu Allahabad, India, 1935; 785-788.
The Wealth of India-Raw Materials. PID, CSIR, New Delhi, 1988; 341-346.
The Ayurvedic Pharmacopoeia of India Part- I Volume - II. p.78.
Vaidya A, Pandita N. Comparative pharmacognostic and phytochemical studies of flower, leaf and stem extracts of Butea monosperma. Asian Journal of Biomedical and Pharmaceutical Sciences 2017; 7(63):10-8.
Cooke T. The Flora of the Presidency of Bombay, Ed.2.Sree Sarawaty Press Ltd. 1958; 1:395.
Mishra M, Yogendra S. Kumar S. Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry 2000; 54:835-838. https://doi.org/10.1016/S0031-9422(00)00136-9
Das S, Khan ML, Rabha A, Bhattacharjya DK. Ethnomedicinal plants of Manas National Park, Assam, Northeast India, 2009.
Gupta SR, Ravindranath B, Seshadri TR. The glucosides of Butea monosperma. Phytochemistry. 1970; 9(10):2231-5. https://doi.org/10.1016/S0031-9422(00)85390-X
Shah KC, Baxi AJ, Dave KK. Isolation and identification of free sugars and free amino acids from Butea frondosa Roxb flowers. Indian Drugs. 1992; 29(9):422-23.
Sindhia VR, Bairwa R. Plant Review: Butea monosperma. International Journal of Pharmaceutical and Clinical Research 2010; 2(2): 90-94.
The Wealth of India-Raw Materials. CSIR, New Delhi, 1988; 2b:341-346.
Murti P, Bhaskara R, Krishnaswamy H. Proceedings - Indian Academy of Sciences. Section A. 1940; 12A:472-476. https://doi.org/10.1007/BF03172444
More S, Jadhav VM, Kadam VJ. A comprehensive review on Butea monosperma: A valuable traditional plant. International Journal of Botany Studies 2018; 3(1): 65-71.
Prasad RB, Rao YN, Rao SV. Phospholipids of palash (Butea monosperma), papaya (Carica papaya), jangli badam (Sterculia foetida), coriander (Coriandrum sativum) and carrot (Daucus carota) seeds. Journal of the American Oil Chemists' Society. 1987; 64(10):1424-7. https://doi.org/10.1007/BF02636993
Burlia DA, Khadeb AB. Comprehensive review on Butea monosperma (Lam.) Kuntze. Pharmacognosy Reviews 2007; 1(2):333-37.
Tandon SP, Tiwari KP. Saxena VK. Proceedings of the National Academy of Sciences. India, Section A: Physical Sciences. 1969; 39:237-9.
Somani R, Kasture S, Singhai AK. Antidiabetic potential of Butea monosperma in rats. Fitoterapia 2006; 77(2):86-90. https://doi.org/10.1016/j.fitote.2005.11.003
Patil MV, Pawar S, Patil DA. Ethnobotany of Butea monosperma (Lam.) Kuntze in North Maharashtra, India. Natural Product Radiance 2007; 5(4):323-325.
Gupta P, Chauhan NS, Pande M, Pathak A. Phytochemical and pharmacological review on Butea monosperma (Palash). International Journal of Agronomy and Plant Production 2012; 3(7):255-258.
Sehrawat A, Khan TH, Prasad L, Sultana S. Butea monosperma and chemomodulation: Protective role against thioacetamide-mediated hepatic alterations in Wistar rats. Phytomedicine 2006; 13(3):157-63. https://doi.org/10.1016/j.phymed.2004.11.007
Shah KG, Baxi AJ. Phytochemical studies and antioestrogenic activity of butea frondosa flowers. Indian Journal of Pharmaceutical Science 1990; 52(6):272-275.
Bhargava SK. Estrogenic and postcoital anticonceptive activity in rats of butin isolated from Butea monosperma seed. Journal of Ethnopharmacology 1986; 18(1):95-101. https://doi.org/10.1016/0378-8741(86)90046-2
Lavhale MS, Mishra SH. Evaluation of free radical scavenging activity of Butea monosperma Lam. Indian Journal Experimental Biology 2007; 45:376-384.
Schoeller W, Dohrn M, Hohlweg W. Über eine oestrogene Substanz aus der Knolle der siamesischen Schlingpflanze Butea superba. Naturwissenschaften 1940; 28(33):532-533. https://doi.org/10.1007/BF01497766
Mathan G, Fatima G, Saxena AK, Chandan BK, Jaggi BS, Gupta BD, Qazi GN, Balasundaram C, Anand Rajan KD, Kumar VL, Kumar V. Chemoprevention with aqueous extract of Butea monosperma flowers results in normalization of nuclear morphometry and inhibition of a proliferation marker in liver tumors. Phytotherapy Research. 2011; 25(3):324-8. https://doi.org/10.1002/ptr.3249
Sumitra M, Manikandan P, Suguna L. Efficacy of Butea monosperma on dermal wound healing in rats. The International Journal of Biochemistry & Cell Biology. 2005; 37(3):566-73. https://doi.org/10.1016/j.biocel.2004.08.003
Pandey J, Singh D, Mishra MK, Gupta A. Evaluation of diuretic activity of gum of butea monosperma. Journal of Positive School Psychology. 2022; 6(7):3572-87.
Kasture VS, Kasture SB, Chopde CT. Anticonvulsive activity of Butea monosperma flowers in laboratory animals. Pharmacology Biochemistry and Behavior 2002; 72(4):965-972. https://doi.org/10.1016/S0091-3057(02)00815-8
Kasture VS, Chopde CT, Deshmukh VK. Anticonvulsive activity of Albizzia lebbeck, Hibiscus rosa sinesis and Butea monosperma in experimental animals. Journal of Ethnopharmacology 2000; 71(1-2):65-75. https://doi.org/10.1016/S0378-8741(99)00192-0
Panda S, Jafri M, Kar A, Meheta BK. Thyroid inhibitory, antiperoxidative and hypoglycemic effects of stigmasterol isolated from Butea monosperma. Fitoterapia 2009; 80(2):123-126. https://doi.org/10.1016/j.fitote.2008.12.002
Shahavi VM, Desai SK. Anti-inflammatory activity of Butea monosperma flowers. Fitoterapia 2008; 79(2):82-85. https://doi.org/10.1016/j.fitote.2007.06.014
Razdan MK, Kapila K, Bhide NK. Study of the antioestrogenic activity of alcoholic extracts of petals and seeds of Butea frondosa. Indian Journal of Physiology and Pharmacology. 1970; 14:57-60.
Bandara BR, Kumar NS, Wimalasiri KM. Constituents of the stem bark from Butea monosperma (Leguminosae). Journal of the National Science Council of Sri Lanka. 1990; 18(2):97-103. https://doi.org/10.4038/jnsfsr.v18i2.8195
Ramana DB, Singh S, Solanki KR, Negi AS. Nutritive evaluation of some nitrogen and non-nitrogen fixing multipurpose tree species. Animal Feed Science and Technology. 2000; 88(1-2):103-111. https://doi.org/10.1016/S0377-8401(00)00200-5
Gunakkunru A, Padmanaban K, Thirumal P, Pritila J, Parimala G, Vengatesan N, et al. Anti-diarrhoeal activity of Butea monosperma in experimental animals. Journal of Ethnopharmacology 2005; 98(3):241-244. https://doi.org/10.1016/j.jep.2004.12.021
Prashanth D, Asha MK, Amit A, Padmaja R. Anthelmintic activity of Butea monosperma. Fitoterapia 2001; 72(4):421-422. https://doi.org/10.1016/S0367-326X(00)00333-6
Iqbal Z, Lateef M, Jabbar A, Ghayur MN, Gilani AH. In vivo anthelmintic activity of Butea monosperma against Trichostrongylid nematodes in sheep. Fitoterapia 2006; 77(2):137-140. https://doi.org/10.1016/j.fitote.2005.11.013
Wongkham S, Wongkham C, Trisonthi C, Boonsiri P, Simasathiansophon S, Atisook K. Isolation and properties of a lectin from the seeds of Butea monosperma. Plant Science. 1994; 103(2):121-6. https://doi.org/10.1016/0168-9452(94)90199-6
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