Transdermal Patch: A Novel Approach for Transdermal Drug Delivery

  • Chanchal Tiwari Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310
  • Mahima Choudhary Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310
  • Princy Malik Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310
  • PANKAJ KUMAR JAISWAL Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310
  • Reetu Chauhan Lords international college of pharmacy, Alwar Rajasthan, India, 301028

Abstract

A self-contained, covert, medicated adhesive patch known as a transdermal patch offers a practical mode of delivery for a range of skin and body problems. Multiple drug administration has several disadvantages including inconvenient administration, the risk of overdose, lack of patient compliance, and drug plasma level fluctuations. Transdermal medication delivery has emerged as a creative means of achieving systemic drug absorption at a predefined rate over an extended period. Its primary benefits are reduced dose frequency, avoiding first-pass metabolism by entering directly into the systemic circulation, suitability for elderly patients who cannot take pharmaceuticals orally, and ability to be self-administered with fewer adverse effects. This review covers general aspects like drug absorption pathways through the skin, the kinetics of drug absorption, different factors affecting the transdermal permeability, various types of transdermal patches, their components, and evaluation parameters. Additionally, some marketed transdermal patches and therapeutic applications of transdermal drug delivery systems have been discussed. Moreover, the article includes various generations of advancements in the transdermal drug delivery system and its future aspect.


Keywords- Transdermal patch, Permeability, Polymer Matrix, Rate Controlling Membrane, Permeation Enhancers.

Keywords: Transdermal patch, Permeability, Polymer Matrix, Rate Controlling Membrane, Permeation Enhancers

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Author Biographies

Chanchal Tiwari, Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Mahima Choudhary, Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Princy Malik, Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

PANKAJ KUMAR JAISWAL, Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, Uttar Pradesh, India 201310

Reetu Chauhan, Lords international college of pharmacy, Alwar Rajasthan, India, 301028

Lords international college of pharmacy, Alwar Rajasthan, India, 301028

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Tiwari C, Choudhary M, Malik P, JAISWAL P, Chauhan R. Transdermal Patch: A Novel Approach for Transdermal Drug Delivery. JDDT [Internet]. 15Nov.2022 [cited 9Dec.2022];12(6):179-88. Available from: https://jddtonline.info/index.php/jddt/article/view/5779

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