Drug Utilization Pattern of Anti-Diabetic Medication: A Prospective Observational Study

A PROSPECTIVE OBSERVATIONAL STUDY

Authors

Abstract

Background: Diabetes mellitus is a chronic disease and is responsible for the significant morbidity and mortality. It is critical to conduct a drug use research of anti-diabetic medications in order to encourage rational drug use in diabetes.

Objective: The purpose of this study was to analyze the pattern of drug use of antidiabetic drugs, as well as the prevalence of diabetes and related risk factors throughout treatment period in our sample group.

Materials & methods: This is a prospective observational research involving 200 secondary care hospital in-patients. During a 6-month period, the prescribing pattern was studied and assessed, and drug-related difficulties in subsequent patients were report.

Results: Among 200 patients, 111 (55.46%) were male and 89 (44.5%) were female. Subject of age  65-80 (n=73) were observed to be more suspected. Hypertension 130 (61.32%) was the most common risk factors. In 200 cases, the most commonly used therapy was monotherapy in 89 subjects (44.5%) followed by combination therapy 55(27.5%). Insulin 192(54.5%) was most commonly used followed by oral drugs 160 (45.4%). The most usually prescribed monotherapy was metformin, followed by glimepiride, while the most commonly prescribed combination therapy were metformin+glimepiride.

Conclusion: Prescribing pattern of drugs in diabetic patients concluded that optimized drug therapy led to minimal ensuing DRPs. A continuous observation and reporting of the prescribing practice of anti-diabetic drugs can help the physicians result in therapeutically effective treatment for the patients.

Keywords: Antidiabetics, Drug utilization pattern, Drug related problem, Comorbidities, metformin

Keywords:

Antidiabetics, Drug utilization pattern, Drug related problem, Comorbidities, metformin

DOI

https://doi.org/10.22270/jddt.v12i2-S.5399

Author Biographies

Celeste Linggi, K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

Fathima Shukoor, K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

Raveendran Divya, K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

Ganne kavyasree, K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

Sanat B Nyamagoud, K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

R B Mahendrakumar, K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

K.L.E. Society’s, College of Pharmacy, Hubballi 580031, India

References

Holt, Richard, et al. Textbook of Diabetes. 5th ed., Wiley-Blackwell, 2017

Parthasarathi G, Hansen N K, Naha C N. A textbook of clinical pharmacy practice Medication review.2nd edition: 447-448.

Ma C S. Role of pharmacists in optimizing the use of anticancer drugs in the clinical setting. Journal of Integrated Pharmacy Research and Practice 2014; 3:11-24. https://doi.org/10.2147/IPRP.S40428

Viktil K K and Blix H S. Impact of clinical pharmacists on drug related problems and clinical outcomes. Journal of Basic Pharmacology and Toxicology 2008; 102:275-280. https://doi.org/10.1111/j.1742-7843.2007.00206.x

Van den Bemt, P., Egberts, T., de Jong-van den Berg, L. And Brouwers, J. Drug-Related Problems in Hospitalized Patients,. Drug Safety, 2000; 22(4):321-333. https://doi.org/10.2165/00002018-200022040-00005

Alex SM, Bs S, Smitha S, Kn J, Menon AS, P UD. Drug utilization pattern of antidiabetic drugs among diabetic outpatients in a tertiary care hospital. Asian J Pharm Clin Res. 2015; 144-6.

Patil D. A Study of Drug Use in Type 2 Diabetes Mellitus with and Without Comorbidities in Patients Visiting A Tertiary Care Hospital. Journal of Medical Science and Clinical Research. 2017; 05(05):21395-21403. https://doi.org/10.18535/jmscr/v5i5.30

Verma S, Drug Utilization Evaluation of Anti-Diabetic Medication through Prescription Monitoring Asian Journal of Pharmaceutical Research and Development, 2019; 7(3):75-77. https://doi.org/10.22270/ajprd.v7i3.537

Das A, Dutta A, Maitiy A, Sarkar D, Nandy M, Ghosh J. Prescribing pattern of antidiabetic drugs in type 2 diabetes mellitus at a tertiary care hospital in Eastern India. International Journal of Community Medicine and Public Health. 2021; 8(2):721. https://doi.org/10.18203/2394-6040.ijcmph20210228

Begum, Ramesh, Prahlad, Bhawani, Drug Utilization Study Of Anti-Diabetic Drugs In A Tertiary Care Hospital The Pharma Innovation Journal 2019; 8(6):1033-1038

Published

2022-04-15
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How to Cite

1.
Linggi C, Shukoor F, Divya R, kavyasree G, Nyamagoud SB, Mahendrakumar RB. Drug Utilization Pattern of Anti-Diabetic Medication: A Prospective Observational Study: A PROSPECTIVE OBSERVATIONAL STUDY. J. Drug Delivery Ther. [Internet]. 2022 Apr. 15 [cited 2026 Jan. 21];12(2-S):14-8. Available from: https://jddtonline.info/index.php/jddt/article/view/5399

How to Cite

1.
Linggi C, Shukoor F, Divya R, kavyasree G, Nyamagoud SB, Mahendrakumar RB. Drug Utilization Pattern of Anti-Diabetic Medication: A Prospective Observational Study: A PROSPECTIVE OBSERVATIONAL STUDY. J. Drug Delivery Ther. [Internet]. 2022 Apr. 15 [cited 2026 Jan. 21];12(2-S):14-8. Available from: https://jddtonline.info/index.php/jddt/article/view/5399