A Case Report on Multiple Adverse Events Associated with Systemic Usage of Dexamethasone
Dexamethasone is a corticosteroid used in the management of various allergic conditions, inflammatory and autoimmune disorders such as rheumatoid arthritis, nausea and vomiting associated with cancer chemotherapy, multiple sclerosis, cerebral edema. ADRs associated usage of corticosteroids includes steroid-induced hyperglycemia, osteoporosis, dyslipidemia, steroid-induced Cushing syndrome, cataracts, increased risk of infections, and thinning of the skin. Cushing's syndrome is a hormonal disorder triggered due to chronic exposure of body tissues to high levels of cortisol. As corticosteroids are widely used by physicians for the management of various inflammatory disorders, patients must be warned about the possible ADRs associated with chronic use. In summary, this is a case of a patient who developed multiple adverse events after usage of dexamethasone that is evident by clinical features and laboratory investigations for which the patient was successfully provided with symptomatic and supportive care.
Keywords: Adverse Drug Reaction (ADR), Buffalo hump, Hyperglycaemia, Osteoporosis.
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