Formulation and Evaluation of Flax Herbal Suppositories

Authors

  • Preeti Mishra Faculty of Pharmacy, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India
  • Rajat Singh B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India
  • Garima Kumari B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India
  • Neha Kumari B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India
  • Amit Kumar Verma Faculty, Department of Pharmacy, MJP Rohilkhand University Bareilly, Uttar Pradesh, India

Abstract

The rectal route has proven its worth in terms of achieving successful drug delivery both locally and systematically. The primary goal of this invention was to develop and evaluate Flax suppositories. To administer its herbal powder to internal sites, suppositories are placed directly into the rectum. A suppository comprises flax as a main active ingredient, administered through the rectal route, used as a laxative, and treatment of haemorrhoids and bacterial infections of the anus. For the formulation of the present invention, the suppository preferably comprises flax in an inert base, which may comprise any suitable inert pharmaceutical carrier. The base may optionally be any suitable inert base that is solid at room temperature. The flax may optionally comprise the liquid or gel form or a dry extract of the juice, or any other form of flax, all of which are collectively termed “flax extract”.

Keywords: Flax extract, suppository, Gelatin, Glycerine, Herbal suppositories.

Keywords:

Flax extract, suppository, Gelatin, Glycerine, Herbal suppositories

DOI

https://doi.org/10.22270/jddt.v12i1.5253

Author Biographies

Preeti Mishra, Faculty of Pharmacy, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

Faculty of Pharmacy, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

Rajat Singh, B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

Garima Kumari, B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

Neha Kumari, B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

B. Pharma, Scholar, Raja Balwant Singh Engineering Technical Campus, Bichpuri, Agra, Uttar Pradesh, India

Amit Kumar Verma, Faculty, Department of Pharmacy, MJP Rohilkhand University Bareilly, Uttar Pradesh, India

Faculty, Department of Pharmacy, MJP Rohilkhand University Bareilly, Uttar Pradesh, India

References

Khar, R.K., Hans, R., Thomas, S.D., Coben, L.J., and Lieberman, H.A., “Suppositories” in The Theory and Practice of Industrial Pharmacy, 4th Edition, CBS Publishers and Distributors, New Delhi, 2013, pp. 744-745.

Advantages and disadvantages of the suppositories dosage form; (n.d.); Retrieved from https://chrominfo.blogspot.com/2021/03/Advantages-and-disadvantages-of-suppositories-dosage-form.html

Loyd V. Allen, “Introduction to Suppositories” in Suppositories Pharmaceutical Press, London, 2008, pp. 5.

Gutte Krishna B., Sahoo A.K., Ranveer Rahul C.; Bioactive Components of Flaxseed and its Health Benefits; International Journal of Pharmaceutical Sciences Review and Research, January 2015, pp. 42-51.

Ziolkovska, A., Laws of flaxseed mucilage extraction, Food Hydrocolloids, Volume 26, Issue 1, January 2012, pp. 198-199. https://doi.org/10.1016/j.foodhyd.2011.04.022

Varshney Himanshu M; Asian Journal of Pharmaceutical and Clinical Research, 2012; 5(4):235-238

Tarkase K. N. and Danve A. V.; Formulation evaluation and in-vitro drug release characteristics of aloe vera herbal suppositories; Der Pharmacia Lettre, 2015; 7(2):310-316

Mishra Manisha U.; Preliminary Evaluation of Mesalamine suppositories using sal fat as a novel base; Journal of Advanced Science Research, 2013; 4(3):37-40.

Indian Pharmacopeia, 8th Edition, Indian Pharmacopoeia Commission (IPC); 2018; 299-310, 349, 350.

Published

2022-01-15
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How to Cite

1.
Mishra P, Singh R, Kumari G, Kumari N, Verma AK. Formulation and Evaluation of Flax Herbal Suppositories. J. Drug Delivery Ther. [Internet]. 2022 Jan. 15 [cited 2026 Jan. 21];12(1):19-22. Available from: https://jddtonline.info/index.php/jddt/article/view/5253

How to Cite

1.
Mishra P, Singh R, Kumari G, Kumari N, Verma AK. Formulation and Evaluation of Flax Herbal Suppositories. J. Drug Delivery Ther. [Internet]. 2022 Jan. 15 [cited 2026 Jan. 21];12(1):19-22. Available from: https://jddtonline.info/index.php/jddt/article/view/5253