Characterization and Screening of Phytochemical Secondary Metabolite of Seri (Muntingia calabura, L) Leaves which is Potential as an Anti-Diabetic based on Indonesian Herbal Medicine Standard
Indonesia has abundant natural resources, especially plants that can be used as raw material for herbal medicine. One of the plants is seri plant (Muntingia calabura, L.). The potential plant part in this study is the leaf part. The leaves of M. calabura were taken from plants that have produced fruit in fresh conditions, cleaned and dried in an open space protected from direct sunlight. The simplicia was powdered and then quartered, then extracted with ethanol as a solvent. The simplicia powder and extract obtained were screened for phytochemicals using the standard method. The characterization results showed that the simplicia powder and extract met the national standard of quality for Indonesian herbal medicines, both the simplicia powder and the extract contained secondary metabolites, including alkaloids, flavonoids, triterpenoids and steroids, saponins and tannins. The process of preparing and organizing samples from the leaves of this plant met the quality standards of Indonesian national herbal medicine and has the potential to be tested as an anti-diabetic.
Keywords: Seri Leaves, characterization, phytochemical screening, quality standards, and anti-diabetic
2. Sibi G, Naveen R, Dhananjaya K, Ravikumar K.R, Mallesha H. Potential Use of Muntingia calabura L. Extracts Against Human and Plant Pathogens. Pharmacognosy Journal 2012; 4(34):44-47
3. Maqbool M, Dar M.A, Gani I, Mir S.A, Khan M. Herbal Medicines as An Alternative Source of Therapy: A Review. World Journal of Pharmacy and Pharmaceutical Sciences 2019; 3(2):374-380
4. Gurning K, Sinaga H. In Vitro Anti-Diabetic Potential Extract Test of Seri (Muntingia calabura, L.) Leaves. Asian Journal of Pharmaceutical Research and Development 2020; 8(6)
5. Pertiwi R.D, Suwaldi, Martien R, Setyowati E.R. Radical Scavenging Activity and Quercetin Content of Muntingia calabura L. Leaves Extracted by Various Ethanol Concentration. Journal Food and Pharmaceutical Sciences 2020; 8(1):174-184
6. Zakaria Z.A, Mohamed M, Mohd N.S, Rofiee M.S, Hussain M.K, Sulaiman M.R, Teh I.K, Salleh M.Z. In Vitro Antiproliferative and Antioxidant Activities of the Extracts of Muntingia calabura Leaves. The American Journal of Chinese Medicine 2011; 39(1):183-200
7. Sarimana J, Adnayana I.K, Sukandar E.Y, Kurniati N.F. The Antirheumatic Activity of Muntingia calabura L. Leaves Ethanol Extract and Its Fraction. Asian Journal of Pharmaceutical and Clinical Research 2017; 10(1):84-86
8. Gurning, K. Identification of Secondary Metabolic and Test of Activity Ethyl Acetate Fraction of Bangun-Bangun (Coleus amboinicus Lour.) Leaves As Antioxidant. Biolink 2020; 7(1):117-122
9. Gul R, Jan S.U, Fardullah S, Sherani S, Jahan N. Preliminary Phytochemical Screening, Quantitative Analysis of Alkaloids, and Antioxidant Activity of Crude Plant Extracts from Ephedra intermedia Indigenous to Balochistan. Hindawi The Scientific World Journal. 2017; 1-7
10. Gurning K, Boangmanalu R, Simanjuntak H.A, Singarimbun N, Rahmiati R, Lestari W. Identification of Sekondari Metabolites and Antidiarrheal Activity of Pirdot Leaves Ethanol Exract (Saurauia vulcani Korth) from West Pakpak, North Sumatera Province, Indonesia. Rasayan Journal of Chemistry 2020; 13(4):2385-2389
11. Depkes RI. 2000. Parameter standar umum ekstrak tumbuhan obat. Jakarta: Departemen Kesehatan Republik Indonesia
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