Nanosponges: A New Drug Delivery System

Authors

  • Savita Mandan Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra
  • Maitreyee Chavan Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra
  • Yamini Bhadane Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra
  • Chetan Kalal Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Abstract

Frustrated from the complex chemistry of the drugs have troubled the researchers in finding the ideal drug. Effective targeted drug delivery system has always been the dream. It has also long been a problem for medical researchers i.e., how to get them to the target organ in the body and how to control the release of the drug to prevent overdoses. The development of new and complex molecule called Nanosponges is proving promising to solve this problem.

Keywords: Nanosponges, Drug delivery

Author Biographies

Savita Mandan, Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Maitreyee Chavan, Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Yamini Bhadane, Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Chetan Kalal, Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Research and Education, Shirpur, Maharashtra

References

Lambert, T. 2016. A brief history of medicine [Online]. Local Histories. Available: http://www.localhistories.org/medicine.html

Krukemeyer, M., Krenn, V., Huebner, F., Wagner, W. & Resch, R. 2015. History and Possible Uses of Nanomedicine Based on Nanoparticles and Nanotechnological Progress. Journal of Nanomedicine & Nanotechnology, 6, 1.

Wagner, V., Dullaart, A., Bock, A.-K. & Zweck, A. 2006. The emerging nanomedicine landscape. Nat Biotech, 24, 1211-1217.

Kalepu, S. & Nekkanti, V. Insoluble drug delivery strategies: review of recent advances and business prospects. Acta Pharmaceutica Sinica B, 2015; 5:442-453.

Ventola, C. L. 2012. The nanomedicine revolution: part 1: emerging concepts. Pt, 37, 512-25.

Fang, R. H., Hu, C. M. & Zhang, L. Nanoparticles disguised as red blood cells to evade the immune system. Expert Opin Biol Ther, 2012; 12:385-9.

Kumari, A., Yadav, S. K. & Yadav, S. C. Biodegradable polymeric nanoparticles based drug delivery systems. Colloids and Surfaces B: Biointerfaces, 2010; 75:1-18.

Meyer, R. A., Sunshine, J. C. & Green, J. J. Biomimetic particles as therapeutics. Trends Biotechnol, 2015; 33:514-24.

Hu, C. M., Fang, R. H., Luk, B. T. & Zhang, L. Polymeric nanotherapeutics: clinical development and advances in stealth functionalization strategies. Nanoscale, 2014; 6:65-75.

Antonelli, A., Sfara, C., Rahmer, J., Gleich, B., Borgert, J. & Magnani, M. Red blood cells as carriers in magnetic particle imaging. Biomed Tech (Berl), 58, 517-25.

Krishnamurthy, S., Gnanasammandhan, M. K., Xie, C., Huang, K., Cui, M. Y. & Chan, J. M. 2016. Monocyte cell membrane -derived nanoghosts for targeted cancer therapy. Nanoscale, 2013; 8:6981-6985.

Roberta C, Francesco T, Wander T. Cyclodextrin based nanosponges for drug delivery, J inclphenom Macrocycl Chem, 2006; 56:209-213.

L. Guo, G. Gao, X. Liu and F. Liu, Preparation and characterization of TiO2 nanosponge, Mater. Chem. Phys. 2008; 111 :22–325.

Amber V., Shailendra S., Swarnalatha S., Cyclodextrin based novel drug delivery systems. J Incl Phenom Macrocycl Chem., 2008; 62:23-42.

Rajeswari C., Alka A., Javed A., Khar R K., Cyclodextrins in drug delivery: an update review. AAPS pharm Sci Tech, 2005; 6(2):E329-E357.

David F. Nanosponge drug delivery system more effective than direct injection.www.physorg.com 01.06.2010, accessed on 20.12.2011.

Jenny A, Merima P, Alberto F and Francesco T. Role of β- cyclodextrin nanosponges in polypropylene photooxidation. Carbohydrate Polymers 2011; 86: 27– 135.

Renuka S and Kamla P. Polymeric nanosponges as an alternative carrier for improved retention of econazole nitrate onto the skin through topicalhydrogel formulation. Pharm DevTechnol 2011; 16:367-376.

Patel SB, Patel HJ and Seth AK, “Nanosponge Drug Delivery System: An Overview”, Journal of Global Pharma Tech., 2010; 2(8):1-9.

Nacht S, Kantz M, “The Microsponge: A Novel Topical Programmable Delivery System, In: Topical Drug Delivery Systems”, David WO, Anfon H A editors. New York: Marcel Dekker, 1992; 42:299-325.

Guo L, Gao G, Liu X and Liu F, “Preparation and characterization of TiO2 nanosponge”, Mater. Chem. Phys. 2008; 111:322–325.

Swaminathan S, Cavalli R, Trotta F and Vavia PR . Formulation of betacyclodextrin based nanosponges of itraconazole. J. Incl. Phemon. Macrocycl.Chem 2007; 57:89-94.

Uday B. Bolmal, F.V. Manvi, Kotha Rajkumar, Sai Sowjanya Palla, Anusha Paladugu1 and Korivi Ramamohan Reddy, Recent Advances in Nanosponges as Drug Delivery System, International Journal of Pharmaceutical Sciences and Nanotechnology, 2013; 6(1).

Honey Tiwari et al. A Review on Nanosponges, World Journal of Pharmacy and Pharmaceutical Science, 2014; 3(11).

Published

2019-04-20
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How to Cite

1.
Mandan S, Chavan M, Bhadane Y, Kalal C. Nanosponges: A New Drug Delivery System. J. Drug Delivery Ther. [Internet]. 2019 Apr. 20 [cited 2026 Jan. 21];8(6-A):141-3. Available from: https://jddtonline.info/index.php/jddt/article/view/2789

How to Cite

1.
Mandan S, Chavan M, Bhadane Y, Kalal C. Nanosponges: A New Drug Delivery System. J. Drug Delivery Ther. [Internet]. 2019 Apr. 20 [cited 2026 Jan. 21];8(6-A):141-3. Available from: https://jddtonline.info/index.php/jddt/article/view/2789