Antioxidant Activity of Centaurium erythraea Extracts

  • Mounira Merghem Laboratory of Phytotherapy Applied to Chronic Diseases, Department of biology and animal physiology, Faculty of Natural and Life Sciences, Ferhat Abbas University, Sétif 19000, Algeria
  • Saliha Dahamna Laboratory of Phytotherapy Applied to Chronic Diseases, Department of biology and animal physiology, Faculty of Natural and Life Sciences, Ferhat Abbas University, Sétif 19000, Algeria

Abstract

Phototherapy has known a great evolution all the world and some medicinal plants are importance remedies of some diseases. Centaurium erythraea is one of the medicinal plants widely used in this field. In this study, we have evaluated the total polyphenolic and the flavonoid contents of the methanolic (ME) and aqueous (AqE) extracts of the plant Centaurium erythraea as well as its antioxidant activity using the DPPH (2'2-diphenylpicrylhydrazyl), β-carotene /linoleic acid bleaching and reducing power assays. The total polyphenolic content of the methanolic extract was 35,45± 0,041 μg AGE/mg extract and flavonoids was 6,65 ± 0,060 μg QE/mg. The total polyphenolic content of the aqueous extract was 54,27 ± 0,023 μg AGE/mg extract and flavonoids was 3,275 ± 0,003 μg QE/mg. The results of the DPPH test showed a powerful antioxidant activity with a very similar IC50 for the methanolic (IC50=0.232 ± 0.002mg/ml) and aqueous (0.208 ± 0.002mg/ml) extracts. The inhibitory activity of the tow extracts in the β-carotene/linoleic acid assay was (86.781 ± 0.17%) for the methanolic extract and (77.816 ± 0.69%) for the aqueous extract. ME has the higher reducing power (IC50 = 0.35 ± 0.066 mg / ml) compared to the AqE (IC50 = 1.31 ± 0.047 mg / ml).


Keywords: Centaurium erythraea, antioxidant activity, polyphenols, DPPH scavenging, β-carotene, reducing power.

Keywords: Centaurium erythraea, antioxidant activity, polyphenols, DPPH scavenging, β-carotene

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Author Biographies

Mounira Merghem, Laboratory of Phytotherapy Applied to Chronic Diseases, Department of biology and animal physiology, Faculty of Natural and Life Sciences, Ferhat Abbas University, Sétif 19000, Algeria

Laboratory of Phytotherapy Applied to Chronic Diseases, Department of biology and animal physiology, Faculty of Natural and Life Sciences, Ferhat Abbas University, Sétif 19000, Algeria

Saliha Dahamna, Laboratory of Phytotherapy Applied to Chronic Diseases, Department of biology and animal physiology, Faculty of Natural and Life Sciences, Ferhat Abbas University, Sétif 19000, Algeria

Laboratory of Phytotherapy Applied to Chronic Diseases, Department of biology and animal physiology, Faculty of Natural and Life Sciences, Ferhat Abbas University, Sétif 19000, Algeria

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Merghem M, Dahamna S. Antioxidant Activity of Centaurium erythraea Extracts. JDDT [Internet]. 15Mar.2020 [cited 8Jul.2020];10(2):171-4. Available from: http://jddtonline.info/index.php/jddt/article/view/3935