REVIEW OF RECENT STUDIES ON STATISTICAL OPTIMIZATION IN DRUG DELIVERY TECHNOLOGIES

Authors

  • Sumit Patil Department of Pharmaceutics, Sai Nath University, Ranchi, Jharkhand, India.
  • Shriniwas Yeramwar Department of Pharmaceutics, Sai Nath University, Ranchi, Jharkhand, India.
  • Pankaj Sharma School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India.
  • Anurag Bhargava Ch. Devi Lal College of Pharmacy Bhagwangah, Jagadhri, Yamuna Nagar, Haryana, India.

Abstract

Statistical modeling and experimental design are essential tools in field of drug delivery during product development and can be divided into formula and process optimization. Experimental design allows efficient experimentation in which all or a large subset of factors are together varied over a set of experiments, in contrast to the traditional approach of varying only one variable at time (OVAT). Good estimates for the required composition, geometry, dimensions and preparation procedure of various types of delivery systems will be available, taking into account the desired administration route, drug dose and release profile. Thus, the number of required experimental studies during product development can be significantly reduced, saving time and reducing costs. The present review discusses types of designs and methodologies used recently in academic as well as industrial research for optimization of novel drug delivery systems.

DOI

https://doi.org/10.22270/jddt.v4i5.954

Published

2014-09-14
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How to Cite

1.
Patil S, Yeramwar S, Sharma P, Bhargava A. REVIEW OF RECENT STUDIES ON STATISTICAL OPTIMIZATION IN DRUG DELIVERY TECHNOLOGIES. J. Drug Delivery Ther. [Internet]. 2014 Sep. 14 [cited 2026 Jan. 14];4(5):58-6. Available from: https://jddtonline.info/index.php/jddt/article/view/954

Issue

Vol. 4 No. 5 (2014): Volume 4, Issue 5, Sep-Oct, 2014

Section

Review

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How to Cite

1.
Patil S, Yeramwar S, Sharma P, Bhargava A. REVIEW OF RECENT STUDIES ON STATISTICAL OPTIMIZATION IN DRUG DELIVERY TECHNOLOGIES. J. Drug Delivery Ther. [Internet]. 2014 Sep. 14 [cited 2026 Jan. 14];4(5):58-6. Available from: https://jddtonline.info/index.php/jddt/article/view/954
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