IN VITRO ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF CALENDULA OFFICINALIS LEAVES
Antioxidant activity of different extracts (water, alcohol and hydroalcohol) of Calendula officinalis leaves was studied for its free radical scavenging property on in vitro models as 1,1-diphenyl-2-picryl hydrazyl (DPPH ). The extract showed good dose-dependent free radical scavenging property. Hydro-alcoholic extract of Calendula officinalis leaves exhibited 82.58% inhibition by scavenging free radicals. In-vitro anti-oxidant studies of Calendula officinalis demonstrated the suppression of both inflammation and arthritis. The results indicate that the antioxidant property of the extract may be due to the high content of phenolic compounds. These results clearly indicate that Calendula officinalis is effective against free radical mediated disease.Keywords: Antioxidant, Calendula officinalis, Free radicals, Phenolic compound, Reductive ability.
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