IN VITRO ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF CALENDULA OFFICINALIS LEAVES

  • Anupam Singh Dev Bhoomi Institute of Pharmacy & Research, Dehradun
  • Kshitij Agarwal Dev Bhoomi Institute of Pharmacy & Research, Dehradun
  • Prem Saini Dev Bhoomi Institute of Pharmacy & Research, Dehradun

Abstract

Antioxidant activity of different extracts (water, alcohol and hydroalcohol) of Calendula officinalis leaves was studied for its free radical scavenging property on in vitro models as 1,1-diphenyl-2-picryl hydrazyl (DPPH ). The extract showed good dose-dependent free radical scavenging property. Hydro-alcoholic extract of Calendula officinalis leaves exhibited 82.58% inhibition by scavenging free radicals. In-vitro anti-oxidant studies of Calendula officinalis demonstrated the suppression of both inflammation and arthritis. The results indicate that the antioxidant property of the extract may be due to the high content of phenolic compounds. These results clearly indicate that Calendula officinalis is effective against free radical mediated disease.

Keywords: Antioxidant, Calendula officinalis, Free radicals, Phenolic compound, Reductive ability.

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1.
Singh A, Agarwal K, Saini P. IN VITRO ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF CALENDULA OFFICINALIS LEAVES. JDDT [Internet]. 14Jul.2014 [cited 18Oct.2021];4(4):74-6. Available from: https://jddtonline.info/index.php/jddt/article/view/897