EXTRACTION AND EVALUATION OF ISAPGHULA SEED POLYMER AS PHARMACEUTICAL EXCIPIENT
Aim of study. Present study includes extraction and characterization the isapghula (Plantago Ovata) seed polymer as pharmaceutical excipients.
Material and methods: By using water based extraction by heating mental isapghula seed polymer was obtained. For characterization of the extracted isapghula seed polymer phyto chemical screening was done and micromeritic properties, flow behavior, Solid forming capacity of polymer was also evaluated.
Results: The result predicts that extracted isapghula seed polymer was soluble in warm water while insoluble in cold water and in organic solvents. It was also exhibited that extracted isapghula seed polymer had good flow properties. pH was found 7.3, this showed that can be used in dosage form without any irritation. Results also showed that this polymer can be used to tablets binder.
Conclusions: From the results it was concluded that evaluated parameters showed that isapghula derived seed polymer can be used as pharmaceutical excipient to prepare solid as well as semisolid dosage form.Key words: Isapghula seed polymer, extraction, characterization, natural polymer, pharmaceutical excipients.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).