ANTIMICROBIAL POTENTIAL OF TUBER PART OF THE TRADITIONAL MEDICINAL CLIMBER, SOLENA AMPLEXICAULIS (LAM.) GANDHI. AGAINST CERTAIN HUMAN

Authors

  • Krishna Moorthy Karthika Department of Botany, Kongunadu Arts and Science College, Coimbatore – 641 029, Tamil Nadu, India
  • Subramaniam Paulsamy Department of Botany, Kongunadu Arts and Science College, Coimbatore – 641 029, Tamil Nadu, India

Abstract

The present study was made to evaluate the in vitro antimicrobial activity of Solena amplexicaulis tuber extracts [hexane, benzene, chloroform, methanol and water] against 15 bacterial and 9 fungal species and to determine the minimum inhibitory concentration (MIC) for its methanolic extract against the above mentioned human pathogens. In vitro antimicrobial activity was determined by using agar disc diffusion technique and MIC was determined by using broth dilution method against certain human pathogen. The results of the study revealed that the chloroform extract showed highest degree of antimicrobial activity against all the microbes tested than the other extracts. The MIC exhibited by methanolic tuber extract against the tested organisms was ranging between 300 and 600μg/mL for bacterial species and between 300 and 500μg/mL for fungal species. S. amplexicaulis tuber extracts especially chloroform extract inhibits the growth of all human pathogens.

Key Words: Antimicrobial activity, Solena amplexicaulis, MIC, chloroform extract.

DOI

https://doi.org/10.22270/jddt.v4i3.829

Published

15-05-2014
Statistics
Abstract Display: 422
PDF Downloads: 498

How to Cite

1.
Karthika KM, Paulsamy S. ANTIMICROBIAL POTENTIAL OF TUBER PART OF THE TRADITIONAL MEDICINAL CLIMBER, SOLENA AMPLEXICAULIS (LAM.) GANDHI. AGAINST CERTAIN HUMAN. J. Drug Delivery Ther. [Internet]. 2014 May 15 [cited 2025 May 13];4(3):113-7. Available from: https://jddtonline.info/index.php/jddt/article/view/829

How to Cite

1.
Karthika KM, Paulsamy S. ANTIMICROBIAL POTENTIAL OF TUBER PART OF THE TRADITIONAL MEDICINAL CLIMBER, SOLENA AMPLEXICAULIS (LAM.) GANDHI. AGAINST CERTAIN HUMAN. J. Drug Delivery Ther. [Internet]. 2014 May 15 [cited 2025 May 13];4(3):113-7. Available from: https://jddtonline.info/index.php/jddt/article/view/829