A Review on Liquisolid Systems

Authors

  • Nilesh Prakashchandra Kala K. B. Institute of Pharmaceutical Education and Research
  • Mohammadsalman Tamizuddin Shaikh K. B. Institute of Pharmaceutical Education and Research
  • Divyesh H Shastri K. B. Institute of Pharmaceutical Education and Research
  • Pragna K Shelat K. B. Institute of Pharmaceutical Education and Research

Abstract

Solubility & dissolution rate enhancement from solid oral dosage form is a key issue for current formulation and development. This review discusses, out of several techniques available, liquisolid system to improve dissolution rate of water insoluble drugs and to enhance dissolution rate of water soluble drugs. Different carriers and coating materials like Fujicalin®, Neusilin®, Avicel®, and Aerosil® can be used as carrier materials to prepare liquisolid system. Various non-volatile solvents like propylene glycol, liquid polyethylene glycols, polysorbates, glycerine, N,N-dimethylacetamide and fixed oils can be used to dissolve water insoluble molecules. Liquid drugs can be mixed directly with carriers to produce liquisolid systems. Liquisolid systems can be used to either enhance or retard drug release.

DOI

https://doi.org/10.22270/jddt.v4i3.828

Author Biographies

Nilesh Prakashchandra Kala, K. B. Institute of Pharmaceutical Education and Research

P.G. Student, Department of Pharmaceutics

Mohammadsalman Tamizuddin Shaikh, K. B. Institute of Pharmaceutical Education and Research

P.G. Student, Department of Pharmaceutics

Divyesh H Shastri, K. B. Institute of Pharmaceutical Education and Research

Assistant Professor, Department of Pharmaceutics

Pragna K Shelat, K. B. Institute of Pharmaceutical Education and Research

Professor, Department of Pharmaceutics

Published

2014-05-15
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How to Cite

1.
Kala NP, Shaikh MT, Shastri DH, Shelat PK. A Review on Liquisolid Systems. J. Drug Delivery Ther. [Internet]. 2014 May 15 [cited 2026 Jan. 22];4(3):25-31. Available from: https://jddtonline.info/index.php/jddt/article/view/828

Issue

Vol. 4 No. 3 (2014): Volume 4, Issue 3, May-June 2014

Section

Review

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How to Cite

1.
Kala NP, Shaikh MT, Shastri DH, Shelat PK. A Review on Liquisolid Systems. J. Drug Delivery Ther. [Internet]. 2014 May 15 [cited 2026 Jan. 22];4(3):25-31. Available from: https://jddtonline.info/index.php/jddt/article/view/828
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