Formulation and Physicochemical Evaluation of Herbal Cold Cream

Authors

  • Prashant Purohit Associate Professor, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India https://orcid.org/0000-0001-5916-1675
  • Gurudev B. Pharm Final Year Researcher, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India
  • Sobha Lakhara B. Pharm Final Year Researcher, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India

Abstract

As the global cosmetic industry shifts toward sustainable and bioactive alternatives, there is a growing demand for products that offer therapeutic benefits without the adverse effects of synthetic chemicals. The primary objective of this research was to develop a stable emollient that provides antimicrobial protection, deep hydration, and skin barrier restoration.

The formulation and evaluation of an herbal cold cream incorporating a synergistic blend of eight natural and medicinal ingredients: Neem oil, Almond oil, Olive oil, Beeswax, Borax, Liquid paraffin, Tulsi extract, and Rose oil.

The formulation utilizes the potent antibacterial and antifungal properties of Neem (Azadirachta indica) and Tulsi (Ocimum tenuiflorum), which contain active compounds like azadirachtin and eugenol to manage acne and minor skin infections. To ensure intense moisturization, Almond and Olive oils were integrated for their high concentrations of omega-3 fatty acids and antioxidants, which combat oxidative stress and sun damage.

The preparation followed a systematic heating and emulsification process, where the oil phase (wax and paraffin) and the aqueous phase (borax and water) were blended at 75°C. Rose oil was added as a final step to provide a natural fragrance and restore the skin’s physiological pH balance. The resulting herbal cold cream offers a comprehensive skincare solution that bridges traditional botanical wisdom with modern dermatological requirements, providing a safe, effective, and nutrient-rich alternative to conventional synthetic creams.The prepared formulation was evaluated for morphological and physiological characteristics, pH, stability, spreadability, and skin irritation. The formulation demonstrated good physical appearance, homogeneity and stability.

Keywords: Phytochemicals, Extraction, Antioxidant, Antibacterial, Polyherbal

Keywords:

Phytochemicals, Extraction, Antioxidant, Antibacterial, Polyherbal

DOI

https://doi.org/10.22270/jddt.v16i6.7795

Author Biographies

Prashant Purohit , Associate Professor, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India

Associate Professor, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India

Gurudev , B. Pharm Final Year Researcher, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India

B. Pharm Final Year Researcher, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India   

Sobha Lakhara , B. Pharm Final Year Researcher, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India

B. Pharm Final Year Researcher, Swami Keshvanand Institute of Pharmacy, Bikaner, 334001, Rajasthan, India   

References

1. Kumar S, Babu G, Reddy YR. Phytochemical screening and stability studies of herbal formulations. Int J Pharm Sci Res. 2013;4(9):3567-3573.

2. Prajapati P, Desai H, Chandarana C. Hand sanitizers as a preventive measure in COVID-19 pandemic, its characteristics, and harmful effects: a review. J Egypt Public Health Assoc. 2022; 97: 6. https://doi.org/10.1186/s42506-021-00094-x PMid:35133535 PMCid:PMC8823197 PMCid:PMC8823197

3. Gambushe SM, Zishiri OT, El Zowalaty ME. Review of Escherichia coli O157:H7 prevalence, pathogenicity, heavy metal and antimicrobial resistance: African perspective. Infect Drug Resist. 2022;15:4645-4673. https://doi.org/10.2147/IDR.S365269 PMid:36039321 PMCid:PMC9420067

PMid:36039321 PMCid:PMC9420067

4. Morita Y, Tomida J, Kawamura Y. Responses of Pseudomonas aeruginosa to antimicrobials. Front Microbiol. 2014;4:422. https://doi.org/10.3389/fmicb.2013.00422 PMid:24409175 PMCid:PMC3884212 PMCid:PMC3884212

5. Azwanida NN. A review on the extraction methods use in medicinal plants, principle, strength and limitation. Med Aromat Plants. 2015;4:196

6. Yadav M, Chatterji S, Gupta SK, Watal G. Preliminary phytochemical screening of six medicinal plants used in traditional medicine. Int J Pharm Pharm Sci. 2014;6(5):539-542.

7. Prashant Purohit, Mahesh Kumar Kataria. Phytochemicals screening, antioxidant and antimicrobial activity of Carica Papaya leaf extracts. Int J Curr Pharm Sci. 2024 May 15; 16(3):95-98 https://doi.org/10.22159/ijcpr.2024v16i3.4087

8. Doss A. Preliminary phytochemical screening of some Indian medicinal plants. Anc Sci Life. 2009;29(2):12-16

9. Prashant Purohit and Himisha Gaur, Lipid Based Nano Particles in Cancer Therapy, Indo American Journal of Pharmaceutical Research, 4(2023).225-29

10. Goyal S, Sharma P, Ramchandraiahgari RM, Ghosh M. Phytochemical profiling and biological activities of medicinal plants: a comprehensive review. Plants (Basel). 2022;11(20):2011

11. Kumar S, Babu G, Reddy YR. Phytochemical screening and stability studies of herbal formulations. Int J Pharm Sci Res. 2013;4(9):3567-3573

12. Surwase VB, Savale MM, Jadhav RS, Kadam AB, Shinde PP. Polyherbal natural hand sanitizer: formulation and evaluation. J Univ Shanghai Sci Technol. 2021;23(6):932-939. https://doi.org/10.51201/JUSST/21/05360

13. Sakthivel M, Prathap B, Mahendiran R, Arivananthan M, Parthiban M, Naveetha M. Review about liquid dosage form. Int J Res Pharm Pharm Sci. 2021;6(5):24-30

Published

2026-06-15
Statistics
Abstract Display: 0
PDF Downloads: 0
PDF Downloads: 0

How to Cite

1.
Purohit P, Gurudev G, Lakhara S. Formulation and Physicochemical Evaluation of Herbal Cold Cream. J. Drug Delivery Ther. [Internet]. 2026 Jun. 15 [cited 2026 Jun. 15];16(6):80-5. Available from: https://jddtonline.info/index.php/jddt/article/view/7795

How to Cite

1.
Purohit P, Gurudev G, Lakhara S. Formulation and Physicochemical Evaluation of Herbal Cold Cream. J. Drug Delivery Ther. [Internet]. 2026 Jun. 15 [cited 2026 Jun. 15];16(6):80-5. Available from: https://jddtonline.info/index.php/jddt/article/view/7795