A Comprehensive Review on the Morphological, Phytochemical and Pharmacological Properties of Nigella sativa Linn
Abstract
Objective(s): The present review aims to comprehensively summarize the traditional, phytochemical, pharmacological, and therapeutic aspects of Nigella sativa Linn. from both modern and Unani perspectives.
Data Sources: Relevant literature was collected from classical Unani texts, scientific databases, published review articles, pharmacological studies, and clinical research papers related to Nigella sativa.
Study Selection: Published literature describing the historical background, morphology, phytochemistry, pharmacological activities, therapeutic uses, dosage, formulations, and correctives of Nigella sativa was included in this review.
Summary of Contents: Nigella sativa Linn., commonly known as Black seed, Black cumin, or Kalonji, is widely recognized for its remarkable therapeutic properties and has been extensively used in traditional medicine systems and the food industry. In Tibb-e-Nabwi (Prophetic Medicine), it is regarded as one of the most valued healing remedies. The plant contains several important phytoconstituents including fixed oils, essential oils, proteins, alkaloids, and saponins. Thymoquinone, the major active constituent, is responsible for many of its pharmacological activities. According to Unani literature, Kalonji possesses actions such as carminative, anti-inflammatory, analgesic, diuretic, emmenagogue, galactagogue, and expectorant effects. Various experimental and clinical studies have reported its antidiabetic, anticancer, antimicrobial, antioxidant, immunomodulatory, bronchodilator, hepatoprotective, nephroprotective, gastroprotective, and anti-inflammatory activities. Despite extensive information, consolidated data combining both Unani and modern scientific perspectives remain limited.
Conclusion: Nigella sativa is a medicinally significant plant with broad therapeutic potential supported by traditional Unani concepts and contemporary scientific evidence. This review provides comprehensive information regarding its pharmacological importance and therapeutic applications, which may support future research and clinical use.
Keywords: Nigella sativa Linn., Healing Medicine, Kalonji, Thymoquinone, Prophetic Medicine, Anti-inflammatory, Unani Medicine
Keywords:
Nigella sativa Linn., Healing Medicine, Kalonji, Thymoquinone, Prophetic Medicine, Anti-inflammatory, Unani MedicineDOI
https://doi.org/10.22270/jddt.v16i6.7776References
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