Ethnobotanical study and safety assessment of medicinal plants from Guiriko region of Burkina Faso used for their doping properties

Authors

  • Clarisse Ouédraogo Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0009-0005-6689-2210
  • Windmi Kagambéga Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0000-0002-6109-4325
  • Hadidiatou Belem Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;
  • Isaac Saamou Boni Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0000-0003-1882-9688
  • Franck Le Sage Téounviel Somda Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0009-0000-7106-6275
  • Sami E. Kam Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0009-0007-5079-9307
  • Eliasse Zongo Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0000-0001-9885-8301
  • Zacharia Kabré Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0009-0003-6360-5154
  • Emmanuel Zongo Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0009-0005-2360-3669
  • Benjamin K. Koama Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0000-0003-4048-7581
  • Samson Guenné Laboratoire de Biochimie et Chimie Appliquées (LABIOCA), Université Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso https://orcid.org/0000-0001-5405-0861
  • Nabéré Ouattara Université Daniel Ouezzin Coulibaly, BP 176 Dédougou, Burkina Faso ; https://orcid.org/0000-0002-1669-7506
  • Roland N.T. Meda Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; https://orcid.org/0000-0001-7789-280X

Abstract

The use of medicinal plants remains an essential practice in sub-Saharan Africa, where they constitute a major therapeutic and socio-cultural resource objective of the study was to investigate medicinal plants used for doping in the city of Bobo-Dioulasso. Methods: To do this, a semi-structured ethnobotanical survey was first conducted among traditional practitioners. Phytochemical compositions of the plants were analyzed using spectrophotometry. Finally, the acute toxicity of the doping plants was studied by administering a single dose of 5000 mg/kg body weight to NRMI mice, which were observed for 14 days. Results: A total of 50 traditional practitioners and herbalists were interviewed and 25 plants species belonging to 17 botanical families were identified. Based on the frequency of citation, the species Martynia annua Lin (Martyniaceae), Securidaca longepedunculata Fresen (Polygalaceae), and Leptadenia hastata (Pesr.) Decne (Asclepiadaceae) were selected for further study. The leaves (55.13%) and root bark (21.79%) were the most used parts. The phytochemical study revealed the presence of phenolic compounds such as polyphenols, total flavonoids and tannins. The extracts exhibited antioxidant activity. The toxicity test of hydroethanolic extracts of M. annua and L. hastata species in mice established an LD50 indicates no toxicity. Conclusions: This study showed that, in addition to using medicinal plants for healing, the local population also uses them for other purposes.

Keywords: Ethnobotany, Performance-enhancing plants, Phytochemistry, Safety, Burkina Faso

Keywords:

Ethnobotany, Performance-enhancing plants, Phytochemistry, Safety, Burkina Faso

DOI

https://doi.org/10.22270/jddt.v16i6.7774

Author Biographies

Clarisse Ouédraogo , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Windmi Kagambéga , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Hadidiatou Belem , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Isaac Saamou Boni , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Franck Le Sage Téounviel Somda , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Sami E. Kam , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Eliasse Zongo , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Zacharia Kabré , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Emmanuel Zongo , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Benjamin K. Koama , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Samson Guenné , Laboratoire de Biochimie et Chimie Appliquées (LABIOCA), Université Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

 

Nabéré Ouattara, Université Daniel Ouezzin Coulibaly, BP 176 Dédougou, Burkina Faso ;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso; 

Roland N.T. Meda , Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

Laboratory of Research and Teaching in Animal Health and Biotechnology, Nazi-Boni University, Bobo-Dioulasso 01 BP 1091 Burkina Faso;

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Ouédraogo C, Kagambéga W, Belem H, Boni IS, Somda FLST, Kam SE, et al. Ethnobotanical study and safety assessment of medicinal plants from Guiriko region of Burkina Faso used for their doping properties. J. Drug Delivery Ther. [Internet]. 2026 Jun. 15 [cited 2026 Jun. 15];16(6):86-98. Available from: https://jddtonline.info/index.php/jddt/article/view/7774

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Vol. 16 No. 6 (2026): Volume 16, Issue 6, June 2026

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Research

Copyright (c) 2026 Clarisse Ouédraogo , Windmi Kagambéga , Hadidiatou Belem , Isaac Saamou Boni , Franck Le Sage Téounviel Somda , Sami E. Kam , Eliasse Zongo , Zacharia Kabré , Emmanuel Zongo , Benjamin K. Koama , Samson Guenné , Nabéré Ouattara, Roland N.T. Meda

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How to Cite

1.
Ouédraogo C, Kagambéga W, Belem H, Boni IS, Somda FLST, Kam SE, et al. Ethnobotanical study and safety assessment of medicinal plants from Guiriko region of Burkina Faso used for their doping properties. J. Drug Delivery Ther. [Internet]. 2026 Jun. 15 [cited 2026 Jun. 15];16(6):86-98. Available from: https://jddtonline.info/index.php/jddt/article/view/7774
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