Critical Analytical Review of Charkokta Jwarahara Mahakashay: Classical Foundations and Contemporary Pharmacological Correlation

Prasenjit K More; Smita Rai; Suwarna A. Meshram

doi:10.22270/jddt.v16i6.7768

Authors

Prasenjit K. More Final Year PG Scholar, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.
Smita Rai Assistant Professor, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760. https://orcid.org/0000-0001-8780-8931
Suwarna A. Meshram Prof. & HOD, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760. https://orcid.org/0000-0002-0537-8489

Abstract

Jwara (fever) occupies a central position in Ayurvedic nosology due to its systemic impact on metabolic, physiological, and psychological equilibrium. In the Charak Samhita, Acharya Charaka classified medicinal substances into fifty Mahakashayas based on similarity of pharmacodynamic action, among which the jwarahara Mahakashaya is described as the thirty-ninth group, comprising ten drugs: Sariva, Sharkara, Patha, Manjistha, Draksha, Peelu, Parushaka, Abhaya, Amalaki, and Vibhitaki. This review critically evaluates identity, phytochemical composition, and modern pharmacological evidence to establish the scientific rationale for this grouping. The integrated analysis reveals that Jwarahara Mahakashaya represents a rational, stage-specific, and synergetic therapeutic cluster designed to address Ama pachana, Strotoshodhana, Pittashamana, and immunomodulation in Jwara. The classical concepts correlate meaningfully with contemporary biomedical understanding of fever as an inflammatory and immune-mediated process.

Keywords: Jwara, Jwarahara Mahakashaya, Rasapanchaka, Immunomodulation

Keywords:

Jwara, Jwarahara Mahakashay , Rasapanchaka, Immunomodulation, Review article

DOI

https://doi.org/10.22270/jddt.v16i6.7768

Author Biographies

Prasenjit K. More , Final Year PG Scholar, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.

Final Year PG Scholar, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.

Smita Rai , Assistant Professor, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.

Assistant Professor, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.

Suwarna A. Meshram , Prof. & HOD, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.

Prof. & HOD, Department of Dravyaguna Vigyan, Parul Institute of Ayurved and Research, Parul University, Vadodara, Gujarat-391760.

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