Study on Drug Utilization and Prescribing Patterns of Antibiotics in the Pulmonology Department of a Tertiary Care Hospital

Authors

  • Ranjitha Balan Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.
  • Josni Jose Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.
  • Asna Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.
  • T. Tamil Selvan Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.
  • M. Shameer Babu Consultant Pulmonologist, PK Das Institute of Medical Sciences, Vaniamkulam, Palakkad, Kerala, India.

Abstract

Background: The study aimed to evaluate drug utilization and prescribing patterns of antibiotics in the Pulmonology Department of a tertiary care hospital, with emphasis on rationality, adherence to standard treatment guidelines (STGs), and compliance with the National List of Essential Medicines(NLEM).

Methods: A prospective cross-sectional study was conducted in the Pulmonology Department of PK Das Institute of Medical Sciences, Palakkad, including 300 prescriptions from patients diagnosed with respiratory tract infections (RTIs). Data were analyzed using descriptive statistics, WHO core prescribing indicators, and adherence to STGs.

Results: The mean age of the study population was 37.87 ± 22.05 years, with males comprising 53.3%. Cephalosporins (47%) were the most prescribed antibiotics, followed by penicillins (32.7%), macrolides (30.7%), and fluoroquinolones (26.3%). Generic prescribing was minimal (2.2%), while NLEM compliance was high (99.6%). Overall, 9.3% of prescriptions were irrational due to duplication or unnecessary broad-spectrum use.

Conclusion: Although adherence to guidelines was satisfactory, empirical therapy and low generic prescribing remain major issues. Continuous audit and stewardship interventions are vital to promote rational antibiotic use.

Keywords: Antibiotic prescribing, drug utilization, respiratory infections, pulmonology, antimicrobial resistance, stewardship.

Keywords:

Antibiotic prescribing, drug utilization, respiratory infections, pulmonology, antimicrobial resistance, stewardship

DOI

https://doi.org/10.22270/jddt.v15i12.7495

Author Biographies

Ranjitha Balan , Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

Josni Jose , Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

Asna , Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

T. Tamil Selvan , Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

Master of Pharmacy, Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Tiruvillamala, Thrissur, Kerala, India.

M. Shameer Babu , Consultant Pulmonologist, PK Das Institute of Medical Sciences, Vaniamkulam, Palakkad, Kerala, India.

Consultant Pulmonologist, PK Das Institute of Medical Sciences, Vaniamkulam, Palakkad, Kerala, India.

References

1. World Health Organization. Antimicrobial resistance: global report on surveillance. Geneva: WHO; 2024.

2. Yadav M, et al. Assessment of antibiotic use in a tertiary care hospital. Indian J Pharm Pract. 2024;17(2):155–160.

3. Kumar R, et al. Drug utilization study of antibiotics in respiratory tract infections. Int J Basic Clin Pharmacol. 2021;10(3):387–392.

4. Deshmukh V, et al. Evaluation of antibiotic prescribing pattern in a tertiary care hospital. J Clin Diagn Res. 2019;13(5):10–14.

5. Papp M, et al. Antimicrobial resistance trends: a multicenter surveillance study. Clin Microbiol Infect. 2023;29(4):455–463.

6. Shubeilat F, Shubeilat JL. Antimicrobial stewardship challenges in respiratory infections. J Glob Antimicrob Resist. 2024;12(3):45–52.

7. Fésüs A, et al. Hospital antibiotic use and resistance trends in Europe. J Hosp Infect. 2022;120(3):233–241.

8. Pandey M, et al. Antibiotic prescribing and utilization patterns in a teaching hospital. J Pharm Sci. 2022;11(1):34–40.

9. Harrigan JJ, et al. Global burden of antimicrobial resistance: surveillance update. JAMA Netw Open. 2024;7(1):e214913.

10. Kasse GE. Strengthening antimicrobial resistance surveillance in low-income settings. Lancet Glob Health. 2023;11(8):e1221–e1234.

11. Patil S, et al. Prescription trends of antibiotics in clinical practice. Indian J Pharm Sci. 2020;82(4):580–586.

12. Vestesson E, et al. Outpatient antibiotic stewardship and clinical outcomes. BMJ Open. 2023;13(2):e055433.

13. World Health Organization. Practical stewardship bundles for respiratory infections. Geneva: WHO; 2024.

14. Ruiz-Ramos J, et al. Clinical predictors of antibiotic resistance in respiratory infections. Clin Infect Dis. 2023;77(5):1010–1019.

15. Llor C. Antibiotic stewardship in primary care: current perspectives. J Antimicrob Chemother. 2022;77(7):1815–1823.

16. Naagar M, et al. Policy and practice gaps in antibiotic use in hospitals. J Pharm Policy Pract. 2021;14(2):77–85.

17. Tonkin-Crine S, et al. Interventions to improve antibiotic prescribing for respiratory infections. Cochrane Database Syst Rev. 2017;11:CD012332.

18. Butt AA, et al. Antimicrobial resistance and prescribing trends in clinical infections. BMC Infect Dis. 2017;17(1):734.

19. Chowta MN, et al. Pattern of antibiotic use in a tertiary care hospital in India. Indian J Pharmacol. 2016;48(3):240–245.

20. Kotwani A, et al. Prescribing patterns of antibiotics and evaluation of use. J Pharmacol Pharmacother. 2015;6(3):145–150.

Published

2025-12-15
Statistics
Abstract Display: 82
PDF Downloads: 54
PDF Downloads: 12

How to Cite

1.
Balan R, Jose J, Asna D, Selvan TT, Babu MS. Study on Drug Utilization and Prescribing Patterns of Antibiotics in the Pulmonology Department of a Tertiary Care Hospital. J. Drug Delivery Ther. [Internet]. 2025 Dec. 15 [cited 2026 Jan. 21];15(12):43-5. Available from: https://jddtonline.info/index.php/jddt/article/view/7495

How to Cite

1.
Balan R, Jose J, Asna D, Selvan TT, Babu MS. Study on Drug Utilization and Prescribing Patterns of Antibiotics in the Pulmonology Department of a Tertiary Care Hospital. J. Drug Delivery Ther. [Internet]. 2025 Dec. 15 [cited 2026 Jan. 21];15(12):43-5. Available from: https://jddtonline.info/index.php/jddt/article/view/7495