Preformulation Insights into Daidzein: An Isoflavone with Therapeutic Potential
Abstract
Daidzein is a natural isoflavonoid derived from various plants such as soybean, and alfalfa. This research article primarily focuses on the identification of daidzein using a UV spectrophotometer & Fourier-transformed infrared spectrophotometer. The maximum absorbance of daidzein in ethanol was found to be 255 nm which is very close to the standard value. The standard curve was plotted and the regression coefficient value R2 was found to be 0.998. This research article primarily focused on identification tests, procedures, and preliminary studies, including Lambda max, FTIR spectrum analysis, partition coefficients, and melting points. Screening of lipids is also studied in this article. For the preparation of novel formulations, screening of lipids is more critical. Daidzein is completely dissolved in tocopherol α. This article primarily focuses on solubility studies of isoflavonoid (Daidzein), which belongs to the poorly soluble and poorly bioavailable BCS class IV.
Keywords: UV Spectrophotometer, FTIR, Isoflavonoid, Daidzein, BCS class, Lambda max.
Keywords:
UV spectrophotometer, FTIR, , Isoflavonoid,, Daidzein,, BCS Class,, Lembda Max,DOI
https://doi.org/10.22270/jddt.v15i12.7487References
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Copyright (c) 2025 Neha Mandle , Pratibha Sahu, Rajesh Choudhary , Swarnali Das Paul, Jaya Shree
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