Precise Evaluation of the Essential Metal Ions in Oral Rehydration Solution by Flame Emission Spectroscopy

Authors

  • Rupali S. Joshi Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111
  • Shruti G. Dhere Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111
  • Abhijeet H. Dhage Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111
  • Sarthak B. Dhumal Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111
  • Atharva A. Deshpande Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111
  • Komal B. Dhakane Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111
  • Shivani S. Devkate Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Abstract

Three rapid, precise, and reliable analytical methods have been established for determining the concentrations of sodium and potassium in two distinct ORS formulations. The first method, use only one standard means measuring how bright the flame is for a sample solution and comparing it with the brightness of a standard solution, means known solution. The second method uses two standard solutions. It involves standardizing a reference substance using two-point bracketing, and the final result is calculated using mathematical formulas. The third method is a linear curve, which means finding how much of a substance is in a sample by comparing it to other sample with known amount. The concentration of a substance in an unknown sample is determined by measuring its flame intensity and comparing it with that of standards, since flame intensity is directly proportional to concentration. The linear range  for sodium and potassium is in the range of 0-100 μg/ml. The developed methods were effectively utilized for the precise evaluation of sodium and potassium in commercially available ORS formulations. Accurate percentage yield indicate that all three methods are rapid, precise and reliable for the estimation of sodium and potassium in two different formulations of ORS.

 Keywords: Metal ions, Oral Rehydration Solution, Flame emission spectroscopy

Keywords:

Metal ions, Oral Rehydration Solution, Flame emission spectroscopy

DOI

https://doi.org/10.22270/jddt.v15i12.7455

Author Biographies

Rupali S. Joshi, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Shruti G. Dhere, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Abhijeet H. Dhage, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Sarthak B. Dhumal, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Atharva A. Deshpande, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Komal B. Dhakane, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Shivani S. Devkate, Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahilyanagar, (MS), India, 414111

References

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Published

2025-12-15
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How to Cite

1.
Joshi RS, Dhere SG, Dhage AH, Dhumal SB, Deshpande AA, Dhakane KB, et al. Precise Evaluation of the Essential Metal Ions in Oral Rehydration Solution by Flame Emission Spectroscopy. J. Drug Delivery Ther. [Internet]. 2025 Dec. 15 [cited 2026 Jan. 21];15(12):14-7. Available from: https://jddtonline.info/index.php/jddt/article/view/7455

How to Cite

1.
Joshi RS, Dhere SG, Dhage AH, Dhumal SB, Deshpande AA, Dhakane KB, et al. Precise Evaluation of the Essential Metal Ions in Oral Rehydration Solution by Flame Emission Spectroscopy. J. Drug Delivery Ther. [Internet]. 2025 Dec. 15 [cited 2026 Jan. 21];15(12):14-7. Available from: https://jddtonline.info/index.php/jddt/article/view/7455