IN VITRO ANTIOXIDANT ACTIVITY OF WHOLE PLANT OF LEPTADENIA PYROTECHNICA

Authors

  • Sangh Partap Department of Pharmaceutical Chemistry, College of Pharmacy, Teerthankar Mahaveer University, Moradabad, Uttar Pradesh, India, 244001
  • Ujjwal Tewari Department of Pharmacology, College of Pharmacy, Teerthankar Mahaveer University, Moradabad
  • Kuldeep Sharma Department of Pharmacology, College of Pharmacy, Teerthankar Mahaveer University, Moradabad
  • Keshari Kishore Jha Department of Pharmaceutical Chemistry, College of Pharmacy, Teerthankar Mahaveer University, Moradabad, Uttar Pradesh, India, 244001

Abstract

The free radical scavenging potential of methanolic extract of Leptadenia pyrotechnica was studied on in vitro antioxidant models. The antioxidant potential was evaluated by determining the activity of hydrogen peroxide (H2O2) radicals scavenging and 1,1-diphenyl-2-picryl hydrazyl (DPPH) assay. In all these studies, a significant correlation existed between concentrations of the extract and percentage inhibition of free radicals. The extract was also shown to have high phenolic content i.e. 99.09±0.10 μg/mg. These results clearly indicated that MELP could be a potential source of natural antioxidant and effective against free radical mediated diseases.

Keywords:   Antioxidant, In vitro, Lagenaria siceraria, Reactive oxygen species

DOI

https://doi.org/10.22270/jddt.v4i1.742

Published

2014-01-08
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How to Cite

1.
Partap S, Tewari U, Sharma K, Jha KK. IN VITRO ANTIOXIDANT ACTIVITY OF WHOLE PLANT OF LEPTADENIA PYROTECHNICA. J. Drug Delivery Ther. [Internet]. 2014 Jan. 8 [cited 2026 Jan. 21];4(1):40-4. Available from: https://jddtonline.info/index.php/jddt/article/view/742

Issue

Vol. 4 No. 1 (2014): Volume 4, Issue 1, Jan-Feb 2014

Section

Research

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How to Cite

1.
Partap S, Tewari U, Sharma K, Jha KK. IN VITRO ANTIOXIDANT ACTIVITY OF WHOLE PLANT OF LEPTADENIA PYROTECHNICA. J. Drug Delivery Ther. [Internet]. 2014 Jan. 8 [cited 2026 Jan. 21];4(1):40-4. Available from: https://jddtonline.info/index.php/jddt/article/view/742
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