Unani Regimenal Approaches for Pain, Function and Quality of Life in Knee Osteoarthritis: A Rapid Scoping Review of Current Evidence

Authors

  • Mohd Sameer Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0006-4017-9641
  • M.I. Abdul Rehman Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0008-3625-3655
  • Sadique Husain Department of Ilmul Advia (Unani Pharmacology), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0006-3611-7763
  • Altaf Hussain Shah Department of Mahiyatul Amraz (Unani Pathology), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0002-8422-5583
  • Noushiba Khan Department of Tahaffuzi Wa Samaji Tibb (Preventive & Social Medicine), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0008-1487-7432
  • Meraj Meraj Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0001-7594-8272
  • Abdul Rehman Ali Department of Amraz Jild Wa Tazeeniyat, Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India. https://orcid.org/0009-0002-0597-7526

Abstract

Background: Knee osteoarthritis (KOA) is a prevalent degenerative joint disorder that leads to chronic pain and disability. Conventional therapies provide only limited long-term relief and are often associated with adverse effects and high cost. In Unani medicine, KOA is closely related to Wajaʹ al-Rukba, categorized under joint disorders, and managed through various regimenal therapies.

Objective: This scoping review aimed to evaluate the effectiveness of Unani regimenal therapies in the management of KOA.

Methods: A systematic search was conducted across PubMed, Google Scholar, and other relevant databases for studies published between January 2009 and March 2024. Keywords included “Knee osteoarthritis, Wajaʹ al-Rukba, Unani medicine, Greco-Arab medicine.” Eligible studies consisted of clinical trials, observational studies, and case studies assessing outcomes such as the Visual Analogue Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Knee Injury and Osteoarthritis Outcome Score (KOOS).

Results: A total of relevant Unani regimenal therapies were identified, including Hijama (cupping), Dalk (massage), Tadhīn (oiling), Takmīd (fomentation), Ḍimād (poultice), Irsaal-e-‘Alaq (leech therapy), and Qai (emesis). Across multiple studies, these therapies demonstrated statistically significant improvements in pain reduction and functional outcomes (p<0.001 in several trials). Notably, no major adverse effects were reported.

Conclusion: Existing evidence suggests that Unani regimenal therapies are effective and safe in improving pain and function among KOA patients. However, most studies to date are small-scale, single-center, and methodologically heterogeneous. Larger, well-designed randomized controlled trials are needed to validate these findings and establish Unani therapies as cost-effective, complementary options in KOA management.

Keywords: Wajaʹ al-Rukba, Unani medicine, Cupping, Massage, Fomentation, Traditional medicine

Keywords:

Wajaʹ al-Rukba, Unani medicine, Cupping, Massage, Fomentation, Traditional medicine

DOI

https://doi.org/10.22270/jddt.v15i10.7410

Author Biographies

Mohd Sameer, Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

M.I. Abdul Rehman , Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Sadique Husain, Department of Ilmul Advia (Unani Pharmacology), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of Ilmul Advia (Unani Pharmacology), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Altaf Hussain Shah, Department of Mahiyatul Amraz (Unani Pathology), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of Mahiyatul Amraz (Unani Pathology), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Noushiba Khan, Department of Tahaffuzi Wa Samaji Tibb (Preventive & Social Medicine), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of Tahaffuzi Wa Samaji Tibb (Preventive & Social Medicine), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Meraj Meraj, Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of of Ilāj bi’l Tadbīr (Regimenal Therapy), Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Abdul Rehman Ali, Department of Amraz Jild Wa Tazeeniyat, Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

Department of Amraz Jild Wa Tazeeniyat, Hakim Syed Ziaul Hasan Government Unani Medical College & Hospital AYUSH Campus, Nehru Nagar Kolar Bypass Road, Behind MANIT, Bhopal - 462003 (Madhya Pradesh) India.

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Published

2025-10-15
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How to Cite

1.
Sameer M, Abdul Rehman M, Husain S, Shah AH, Khan N, Meraj M, et al. Unani Regimenal Approaches for Pain, Function and Quality of Life in Knee Osteoarthritis: A Rapid Scoping Review of Current Evidence. J. Drug Delivery Ther. [Internet]. 2025 Oct. 15 [cited 2025 Nov. 15];15(10):248-55. Available from: https://jddtonline.info/index.php/jddt/article/view/7410

How to Cite

1.
Sameer M, Abdul Rehman M, Husain S, Shah AH, Khan N, Meraj M, et al. Unani Regimenal Approaches for Pain, Function and Quality of Life in Knee Osteoarthritis: A Rapid Scoping Review of Current Evidence. J. Drug Delivery Ther. [Internet]. 2025 Oct. 15 [cited 2025 Nov. 15];15(10):248-55. Available from: https://jddtonline.info/index.php/jddt/article/view/7410