IN VITRO ANTICANCER EFFECT OF ARTABOTRYS CRASSIFOLIUS HOOK.F. & THOMSON AGAINST HUMAN CARCINOMA CELL LINES

Authors

  • Kok Kwan Tan School of Pharmacy, Faculty of Science, The University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
  • Tracey D Bradshaw Centre for Biomolecular Sciences, School of Pharmacy, The University of Nottingham, University Park, Nottingham NG7 2RD, UK.
  • Jessica Chu Centre for Biomolecular Sciences, School of Pharmacy, The University of Nottingham, University Park, Nottingham NG7 2RD, UK.
  • Teng Jin Khoo School of Pharmacy, Faculty of Science, The University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
  • Christophe Wiart School of Pharmacy, Faculty of Science, The University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.

Abstract

The aim of the present study was to investigate the anticancer effects of crude extracts of Artabotrys crassifolius on the growth of human breast and colorectal carcinoma cell lines. The leaves and barks of Artabotrys crassifolius were extracted sequentially with hexane, chloroform and ethanol. The corresponding crude extracts obtained were then tested for their anticancer activity using MTT assay. Among the extracts studied, chloroform and hexane extracts of barks were found to possess the most potent anticancer activity which necessitates further isolation and characterisation of the bioactive compounds present in the respective extracts.

Keywords: Anticancer, Artabotrys crassifolius, Human carcinoma cell lines

DOI

https://doi.org/10.22270/jddt.v4i1.728

Published

2014-01-08
Statistics
Abstract Display: 691
PDF Downloads: 733

How to Cite

1.
Tan KK, Bradshaw TD, Chu J, Khoo TJ, Wiart C. IN VITRO ANTICANCER EFFECT OF ARTABOTRYS CRASSIFOLIUS HOOK.F. & THOMSON AGAINST HUMAN CARCINOMA CELL LINES. J. Drug Delivery Ther. [Internet]. 2014 Jan. 8 [cited 2026 Jan. 21];4(1):1-4. Available from: https://jddtonline.info/index.php/jddt/article/view/728

Issue

Vol. 4 No. 1 (2014): Volume 4, Issue 1, Jan-Feb 2014

Section

Research

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

How to Cite

1.
Tan KK, Bradshaw TD, Chu J, Khoo TJ, Wiart C. IN VITRO ANTICANCER EFFECT OF ARTABOTRYS CRASSIFOLIUS HOOK.F. & THOMSON AGAINST HUMAN CARCINOMA CELL LINES. J. Drug Delivery Ther. [Internet]. 2014 Jan. 8 [cited 2026 Jan. 21];4(1):1-4. Available from: https://jddtonline.info/index.php/jddt/article/view/728
Crossref
Scopus
Google Scholar
Europe PMC