A Brief Review on Cervical Spondylosis
Abstract
Cervical spondylosis is a common degenerative condition affecting the cervical spine, predominantly in individuals over the age of 40. This comprehensive review explores its epidemiology, pathogenesis, and clinical manifestations, including cervical radiculopathy, myelopathy, and axial joint pain. The degenerative changes, originating from intervertebral disc dehydration and osteophyte formation, lead to symptoms ranging from localized neck pain to neurological deficits. Diagnosis primarily relies on clinical evaluation, supported by imaging modalities such as MRI and CT scans. Non-surgical management includes physical therapy, pharmacological interventions, and alternative therapies, including acupuncture and yoga. For severe or refractory cases, surgical options like anterior cervical discectomy and posterior laminoplasty are discussed. Despite advancements in diagnosis and management, the chronic nature of the condition necessitates a multidisciplinary approach to minimize disability and improve quality of life. This review underscores the need for further research into effective long-term treatments and preventive strategies for cervical spondylosis.
Keywords: Cervical spondylosis Epidemiology, Pathophysiology, Types, Diagnosis, Surgical Treatment, Alternative treatment, non-surgical treatment
Keywords:
Cervical spondylosis Epidemiology,, Pathophysiology, Diagnosis, Surgical Treatment, Alternative treatmentDOI
https://doi.org/10.22270/jddt.v15i7.7235References
1. Bernabéu-Sanz Á, Mollá-Torró JV, López-Celada S, Moreno López P, Fernández-Jover E. MRI evidence of brain atrophy, white matter damage, and functional adaptive changes in patients with cervical spondylosis and prolonged spinal cord compression. Eur Radiol. 2020;30(1):357-69. https://doi.org/10.1007/s00330-019-06352-z PMid:31350584
2. Leung KKY, Chu EC-P, Chin WL, Mok STK, Chin EWS. Cervicogenic visual dysfunction: An understanding of its pathomechanism [Internet]. U.S. National Library of Medicine; 2023 [cited 2025Jun21]Availablefrom:https://pmc.ncbi.nlm.nih.gov/articles/PMC992
3. Chu, E.P., Lo, F. and Bhaumik, A. (2020) 'Plausible impact of forward head posture on upper cervical spine stability', Journal of Family Medicine and Primary Care, 9(5), p. 2517. https://doi.org/10.4103/jfmpc.jfmpc_95_20 PMid:32754534 PMCid:PMC7380784
4. Koh MJ, Park SY, Woo YS, Kang SH, Park SH, Chun HJ, et al. Assessing the prevalence of recurrent neck and shoulder pain in Korean high school male students: a cross-sectional observational study. The Korean Journal of Pain [Internet] 2012;25:161-7. https://doi.org/10.3344/kjp.2012.25.3.161 PMid:22787546 PMCid:PMC3389320
5. Theodore N. Degenerative cervical spondylosis. N Engl J Med. (2020) 383:159-68. https://doi.org/10.1056/NEJMra2003558 PMid:32640134
6. Gao Q-Y, Wei F-L, Zhu K-L, Zhou C-P, Zhang H, Cui W-X, et al. Clinical efficacy and safety of surgical treatments in patients with pure cervical radiculopathy. Front Public Health. (2022) 10:892042. https://doi.org/10.3389/fpubh.2022.892042 PMid:35910906 PMCid:PMC9330161
7. Jiang L, Xu Y, Yang Z, Li P, Dong Y, Yang G. Global trends in cervical spondylosis research: a bibliometric analysis based on the Web of Science. Front Neurol. 2025;16:1541459. https://doi.org/10.3389/fneur.2025.1541459 PMid:40371077 PMCid:PMC12075215
8. Abduljewad B, Mulu A, Ayele B, Mamushet Y. Prevalence of cervical spondylosis and its associated factors among symptomatic adult patients attending tertiary hospital, Ethiopia, 2023. Research Square. 2024. https://doi.org/10.21203/rs.3.rs-4206836/v1
9. Kim D, Kim S, Park J. Quantitative MRI and T2 mapping in cervical disc degeneration: Correlation with clinical symptoms and disc microstructure. Korean J Radiol. 2022;23(3):302-12. doi:10.3348/kjr.2021.0381.
10. Nouri A, Tetreault L, Singh A, Karadimas SK, Fehlings MG. Degenerative cervical myelopathy: Epidemiology, genetics, and pathogenesis. Spine (Phila Pa 1976). 2021;46(9):E520-9. https://doi.org/10.1097/BRS.0000000000003848 PMid:33290373
11. Choi SH, Kang SH. Pathophysiology of cervical spondylotic myelopathy: Clinical relevance and biomechanical insights. Asian Spine J. 2021;15(1):6-14.
12. Karadimas SK, Erwin WM, Ely CG, Dettori JR, Fehlings MG. Pathophysiology and natural history of cervical spondylotic myelopathy. Spine (Phila Pa 1976). 2022;47(1):S17-24. https://doi.org/10.1097/BRS.0000000000004281 PMid:34802027
13. Michiels S, Vysotskiy A, Schils F, Bernardes D. Evaluation of cervical vertebral motion and foraminal changes during the Spurling test using zero echo time MRI. Spine J. 2024;24(2):189 97. https://doi.org/10.1016/j.spinee.2023.10.012
14. Jinright H, Kassoff N, Williams C, Hazle C. Clinical evaluation versus magnetic resonance imaging findings in patients with radicular arm pain-a pragmatic study. Health Sci Rep. 2022;5(2):e589. https://doi.org/10.1002/hsr2.589 PMid:35434382 PMCid:PMC8995534
15. Lee CG, Nam WD. Reliability and diagnostic accuracy of dermatomes/myotomes in cervical radiculopathy. Neurospine. 2022;19:1006 13. https://doi.org/10.14245/ns.2244194.097 PMid:36597659 PMCid:PMC9816603
16. Davies BM, Mowforth OD, Smith EK, Kotter MR. Degenerative cervical myelopathy: diagnosis and management in primary care. J Am Board Fam Med. 2021;33(2):303-16. 17. Ibara T, Matsui R, Nakagawa Y, Nishikawa T, Toyama Y. Screening for degenerative cervical myelopathy with the 10-second grip-and-release test using a smartphone and machine learning: pilot study. Digit Health. 2023;9:20552076231179030. https://doi.org/10.1177/20552076231179030 PMid:37312962 PMCid:PMC10259100
18. Kim HJ, Jun YJ, Kim SH. Functional anatomy and clinical implications of cervical spine syndromes: Focus on Type III syndrome. J Spine Surg. 2023;9(2):102-110. https://doi.org/10.21037/jss-22-456
19. Smith TP, Brown EM, Taylor AJ. Cervical spine joint pathologies: A detailed review of anatomical and clinical features. Int J Orthop Res. 2022;14(3):245-255. https://doi.org/10.1002/jor.23456 PMid:27704611
20. Patel V, Rao S, Kumar N. Radiological and clinical evaluation of referred pain in cervical spine disorders. Clin Orthop Relat Res. 2021;479(1):15-24. https://doi.org/10.1097/CORR.0000000000001453 PMid:32898048 PMCid:PMC7571983
21. Ibrahim AAG, Alahmari AMA, Alsuayri AHF, Algomshah AMM, Almlfi SGS, Alamri ADA, et al. A Review on Diagnosis and Management of Cervical Spondylosis. J Pharm Res Int. 2021;33(47A):668-674. https://doi.org/10.9734/jpri/2021/v33i47A33059
22. Karadimas SK, Erwin WM, Ely CG, Dettori JR, Fehlings MG. Pathophysiology and natural history of cervical spondylotic myelopathy. Spine (Phila Pa 1976). 2022;47(1):S17-24. https://doi.org/10.1097/BRS.0000000000004281 PMid:34802027
23. Lin Y, Zhao X, Qian Z, et al. Added value of 3D fast-field-echo (FRACTURE) MRI sequences for cervical spondylosis diagnosis: A prospective study. Insights Imaging. 2025;(in press). https://doi.org/10.1186/s13244-025-01997-5 PMid:40459683 PMCid:PMC12133650
24. Singh V, Sharma RK. Role of electromyography in diagnosing cervical spondylotic myelopathy. J Clin Neurosci. 2022;99:112-7. https://doi.org/10.1016/j.jocn.2022.04.013 PMid:35453100
25. Sharma N, Gupta S, Rajput A. Diagnostic imaging of cervical spondylosis: Current practices and future directions. J Radiol Imaging Sci. 2024;17(2):85-94. https://doi.org/10.4103/jris.jris_41_23
26. Jawad ZY, Hamdan FB, Nema IS. Neurophysiologic evaluation of patients with cervical spondylotic myelopathy. Egypt J Neurol Psychiatry Neurosurg. 2022;58:166. https://doi.org/10.1186/s41983-022-00595-2
27. Srivastav P, Singh A, Verma A, Kumar R. Diagnostic imaging in cervical spondylosis: Emphasis on CT myelography and discography protocols. J Med Imaging Clin Res. 2023;8(3):145-152. https://doi.org/10.1186/jmicr-2023-07 .
28. Tang Y, Guo F, Wang X. Application of provocative discography in cervical discogenic pain evaluation: A systematic review. Pain Physician. 2025;28(2):145-52. https://doi.org/10.36076/ppj.2025.28.2.145 .
29. Srivastav Y, Prajapati A, Kumar M, Verma A, Manjari. A short overview of cervical spondylosis, including its diagnosis and current treatment strategies. J Adv Med Med Res. 2023;35(22):170-88. https://doi.org/10.9734/jammr/2023/v35i225258
30. chao Y, Wang L, Xu Z, et al. Advances in surgical and non-surgical management of cervical spondylosis: A systematic review. Spine J. 2024;24(1):45-58. https://doi.org/10.1016/j.spinee.2023.07.012 PMid:37473812
31. Chen J, Zhang H, Zhou Q, et al. Comparative outcomes of anterior cervical discectomy and fusion versus laminoplasty for multilevel cervical spondylosis. J Clin Orthop Trauma. 2022;24:102754. https://doi.org/10.1016/j.jcot.2022.102754 .
32. Park K, Lee JH, Kim B. Long-term outcomes of radiofrequency ablation and epidural steroid injections in cervical spondylotic radiculopathy. Clin Spine Surg. 2023;36(2):85-92. https://doi.org/10.1097/BSD.0000000000001357 PMid:35801718
33. Patel N, Rao S, Singh V. Non-surgical treatment of cervical spondylosis: A comprehensive review. J Musculoskelet Neuronal Interact. 2022;22(3):452-60
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