Traditional Wisdom Meets Chronic Disease: Unani Success in Managing Psoriasis with Zimad and Leech Therapy-A Case Report
Abstract
Background: Psoriasis is a chronic, immune-mediated inflammatory skin disorder marked by erythematous plaques with silvery-white scales, significantly affecting patients’ physical and psychological well-being. Conventional therapies, while often effective in symptom control, can result in side effects or limited long-term efficacy. Unani medicine, a traditional holistic system, incorporates unique therapeutic modalities such as Zimad (topical applications) and Taleeq (leech therapy), which aim to restore humoral balance and detoxify the body.
Objective: To evaluate the efficacy of Unani therapeutic interventions, specifically Zimad and Leech therapy, in a patient with chronic psoriasis unresponsive to conventional treatments.
Methods: A 45-year-old female with 15-year history of psoriasis was presented with widespread lesions, erythema, scaling, and pruritus. The patient was treated with Unani regimens like Taleeq (Leech Therapy) in which, two leeches over the affected site were applied twice a week for 10 sittings along with herbal Zimad containing anti-inflammatory and keratolytic properties was applied twice daily. Clinical assessment was performed at baseline, 21st day and 35th day using Psoriasis Area and Severity Index (PASI) and Dermatological Life Quality Index (DLQI).
Results: Marked improvement was observed after 35 days of treatment. Erythema, scaling, and itching were significantly reduced, with a notable decrease in PASI and DLQI scores. The patient reported improved quality of life and no adverse effects. The outcome suggests potential benefits of Unani therapy in managing psoriasis.
Conclusion: This case demonstrates that Unani therapies, particularly Zimad and Taleeq, may offer an effective complementary approach for managing chronic psoriasis, especially in patients who are unresponsive to conventional treatments. These modalities appear to support symptom relief through detoxification and humoral correction without adverse events. Larger-scale clinical studies are warranted to validate these findings.
Keywords: Psoriasis, Taqashshur al-Jild, Zimad, Taleeq, Leech Therapy, Unani
Keywords:
Psoriasis, Taqashshur al-Jild, Zimad, Taleeq, Leech Therapy, UnaniDOI
https://doi.org/10.22270/jddt.v15i6.7214References
1. Lone AH, Ahmad T and Naiyar AH. Clinical evaluation of efficacy of Maj'un Ushba and RoghanHindi in the management of psoriasis: A Randomized Single-Blind, Placebo-Controlled Study. Journal of Ayurveda & Integrative Medicine. 2011; 2(1): Pp.26 -31. https://doi.org/10.4103/0975-9476.78188 PMid:21731384 PMCid:PMC3121250
2. Qureshi MA, Bano H. Clinical observation of Unani medicine in the treatment of Psoriasis: A Case Study.
3. Tabasum H. EFFICACY OF UNANI MEDICATIONS AND TALEEQ (LEECH THERAPY) IN THE MANAGEMENT OF TAQASHSHUR JILD (PSORIASIS)-A CASE REPORT.
4. Arnold KA, Treister AD, Lio PA, Alenghat FJ. Association of Atherosclerosis Prevalence With Age, Race, and Traditional Risk Factors in Patients With Psoriasis. JAMA Dermatol 2019;155(5):622-3. https://doi.org/10.1001/jamadermatol.2018.5462 PMid:30785601 PMCid:PMC6506874
5. Jung KJ, Kim TG, Lee JW, Lee M, Oh J, Lee SE, et al. Increased Risk of Atherosclerotic Cardiovascular Disease Among Patients With Psoriasis in Korea: A 15-Year Nationwide Population-Based Cohort Study. J Dermatol (2019) 46(10):859-66. https://doi.org/10.1111/1346-8138.15052 PMid:31432567
6. Committee of Psoriasis, Dermatology Branch, Chinese Medical Association. Guidelines for the Diagnosis and Treatment of Psoriasis in China: 2019 Concise Edition. Int J Dermatol Venereol 2020;3(1):14-26. https://doi.org/10.1097/JD9.0000000000000074
7. al-Jild T. Effectiveness of Oral and Topical Unani Formulations in Taqashshur Al-Jild (Psoriasis): A Case Study. Indian Journal of Unani Medicine Vol. XIV. 2021 Jul(2):96-101.
8. Khan MA. Ramooz Azam (Persian version). 2nd ed. New Delhi: CCRUM; 2006.
9. Arzani MA. Tibb-e-Akbar (Urdu Translation by Hakeem Mohd Husain). New Delhi: Idara Kitab us Shifa; YNM.
10. Kabeerudin. Sharha-Asbab. New Delhi: Aijaz Publication House; 2007.
11. S M Abbas Zaidi, S S Jameel, F Zaman, Shazia Jilani, A Sultana, Shariq A Khan. A Systematic Overview of the Medicinal Importance of Sanguivorous Leeches. Alternative Medicine Review. 2011;16(1):59-65
12. Ghawi AM, Abdualkader AM, Merzouk A, Alaama M. Free Radical Scavenging Activity of the Medicinal Malaysian Leech Saliva Extract, Hirudinaria manillensis. J Bioequi Availab 2012; S14. https://doi.org/10.4172/jbb.S14-001
13. Nair AS, Sekar M, Gan SH, Kumarasamy V, Subramaniyan V, Wu YS, Mat Rani NN, Ravi S, Wong LS. Lawsone unleashed: A comprehensive review on chemistry, biosynthesis, and therapeutic potentials. Drug Design, Development and Therapy. 2024 Dec 31:3295-313. https://doi.org/10.2147/DDDT.S463545 PMid:39081702 PMCid:PMC11288359
14. Ríos J., Giner R., Marín M., Recio M. A pharmacological update of ellagic acid. Planta Med. 2018;84(15):1068-1093. https://doi.org/10.1055/a-0633-9492 PMid:29847844
15. Akram M, Imtiaz A, Soonmin H. Anti-Inflammatory Effects of Quercus and Other Health Benefits.
16. Jacob J, Gopalan R, Lakshmanaperumalsamy P, Illuri R, Bhosle D, Sangli GK, Mundkinajeddu D. Evaluation of Anti-psoriatic Potential of the Fruit Rind of Punica granatum L. Pharmacognosy Journal. 2019;11(3). https://doi.org/10.5530/pj.2019.11.73
Published
Abstract Display: 523
PDF Downloads: 562
PDF Downloads: 59 How to Cite
Issue
Section
Copyright (c) 2025 Umme Ayman , Shaik Adeena Parveen , Firdous K Fakeha

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

.