Traditional Wisdom Meets Chronic Disease: Unani Success in Managing Psoriasis with Zimad and Leech Therapy-A Case Report

Authors

  • Umme Ayman Assistant Professor, Department of Regimenal Therapies, National Institute of Unani Medicine, Bengaluru, Karnataka, India.
  • Shaik Adeena Parveen PG Scholar, Department of Regimenal Therapies, National Institute of Unani Medicine, Bengaluru, Karnataka, India.
  • Firdous K Fakeha Research Associate, Clinical Research Unit (Unani), Central Council for Research in Unani Medicine, Bengaluru

Abstract

Background: Psoriasis is a chronic, immune-mediated inflammatory skin disorder marked by erythematous plaques with silvery-white scales, significantly affecting patients’ physical and psychological well-being. Conventional therapies, while often effective in symptom control, can result in side effects or limited long-term efficacy. Unani medicine, a traditional holistic system, incorporates unique therapeutic modalities such as Zimad (topical applications) and Taleeq (leech therapy), which aim to restore humoral balance and detoxify the body.

Objective: To evaluate the efficacy of Unani therapeutic interventions, specifically Zimad and Leech therapy, in a patient with chronic psoriasis unresponsive to conventional treatments.

Methods: A 45-year-old female with 15-year history of psoriasis was presented with widespread lesions, erythema, scaling, and pruritus. The patient was treated with Unani regimens like Taleeq (Leech Therapy) in which, two leeches over the affected site were applied twice a week for 10 sittings along with herbal Zimad containing anti-inflammatory and keratolytic properties was applied twice daily. Clinical assessment was performed at baseline, 21st day and 35th day using Psoriasis Area and Severity Index (PASI) and Dermatological Life Quality Index (DLQI).

Results: Marked improvement was observed after 35 days of treatment. Erythema, scaling, and itching were significantly reduced, with a notable decrease in PASI and DLQI scores. The patient reported improved quality of life and no adverse effects. The outcome suggests potential benefits of Unani therapy in managing psoriasis.

Conclusion: This case demonstrates that Unani therapies, particularly Zimad and Taleeq, may offer an effective complementary approach for managing chronic psoriasis, especially in patients who are unresponsive to conventional treatments. These modalities appear to support symptom relief through detoxification and humoral correction without adverse events. Larger-scale clinical studies are warranted to validate these findings.

Keywords: Psoriasis, Taqashshur al-Jild, Zimad, Taleeq, Leech Therapy, Unani

Keywords:

Psoriasis, Taqashshur al-Jild, Zimad, Taleeq, Leech Therapy, Unani

DOI

https://doi.org/10.22270/jddt.v15i6.7214

Author Biographies

Umme Ayman , Assistant Professor, Department of Regimenal Therapies, National Institute of Unani Medicine, Bengaluru, Karnataka, India.

Assistant Professor, Department of Regimenal Therapies, National Institute of Unani Medicine, Bengaluru, Karnataka, India.

Shaik Adeena Parveen , PG Scholar, Department of Regimenal Therapies, National Institute of Unani Medicine, Bengaluru, Karnataka, India.

PG Scholar, Department of Regimenal Therapies, National Institute of Unani Medicine, Bengaluru, Karnataka, India.

Firdous K Fakeha , Research Associate, Clinical Research Unit (Unani), Central Council for Research in Unani Medicine, Bengaluru

Research Associate, Clinical Research Unit (Unani), Central Council for Research in Unani Medicine, Bengaluru

References

1. Lone AH, Ahmad T and Naiyar AH. Clinical evaluation of efficacy of Maj'un Ushba and RoghanHindi in the management of psoriasis: A Randomized Single-Blind, Placebo-Controlled Study. Journal of Ayurveda & Integrative Medicine. 2011; 2(1): Pp.26 -31. https://doi.org/10.4103/0975-9476.78188 PMid:21731384 PMCid:PMC3121250

2. Qureshi MA, Bano H. Clinical observation of Unani medicine in the treatment of Psoriasis: A Case Study.

3. Tabasum H. EFFICACY OF UNANI MEDICATIONS AND TALEEQ (LEECH THERAPY) IN THE MANAGEMENT OF TAQASHSHUR JILD (PSORIASIS)-A CASE REPORT.

4. Arnold KA, Treister AD, Lio PA, Alenghat FJ. Association of Atherosclerosis Prevalence With Age, Race, and Traditional Risk Factors in Patients With Psoriasis. JAMA Dermatol 2019;155(5):622-3. https://doi.org/10.1001/jamadermatol.2018.5462 PMid:30785601 PMCid:PMC6506874

5. Jung KJ, Kim TG, Lee JW, Lee M, Oh J, Lee SE, et al. Increased Risk of Atherosclerotic Cardiovascular Disease Among Patients With Psoriasis in Korea: A 15-Year Nationwide Population-Based Cohort Study. J Dermatol (2019) 46(10):859-66. https://doi.org/10.1111/1346-8138.15052 PMid:31432567

6. Committee of Psoriasis, Dermatology Branch, Chinese Medical Association. Guidelines for the Diagnosis and Treatment of Psoriasis in China: 2019 Concise Edition. Int J Dermatol Venereol 2020;3(1):14-26. https://doi.org/10.1097/JD9.0000000000000074

7. al-Jild T. Effectiveness of Oral and Topical Unani Formulations in Taqashshur Al-Jild (Psoriasis): A Case Study. Indian Journal of Unani Medicine Vol. XIV. 2021 Jul(2):96-101.

8. Khan MA. Ramooz Azam (Persian version). 2nd ed. New Delhi: CCRUM; 2006.

9. Arzani MA. Tibb-e-Akbar (Urdu Translation by Hakeem Mohd Husain). New Delhi: Idara Kitab us Shifa; YNM.

10. Kabeerudin. Sharha-Asbab. New Delhi: Aijaz Publication House; 2007.

11. S M Abbas Zaidi, S S Jameel, F Zaman, Shazia Jilani, A Sultana, Shariq A Khan. A Systematic Overview of the Medicinal Importance of Sanguivorous Leeches. Alternative Medicine Review. 2011;16(1):59-65

12. Ghawi AM, Abdualkader AM, Merzouk A, Alaama M. Free Radical Scavenging Activity of the Medicinal Malaysian Leech Saliva Extract, Hirudinaria manillensis. J Bioequi Availab 2012; S14. https://doi.org/10.4172/jbb.S14-001

13. Nair AS, Sekar M, Gan SH, Kumarasamy V, Subramaniyan V, Wu YS, Mat Rani NN, Ravi S, Wong LS. Lawsone unleashed: A comprehensive review on chemistry, biosynthesis, and therapeutic potentials. Drug Design, Development and Therapy. 2024 Dec 31:3295-313. https://doi.org/10.2147/DDDT.S463545 PMid:39081702 PMCid:PMC11288359

14. Ríos J., Giner R., Marín M., Recio M. A pharmacological update of ellagic acid. Planta Med. 2018;84(15):1068-1093. https://doi.org/10.1055/a-0633-9492 PMid:29847844

15. Akram M, Imtiaz A, Soonmin H. Anti-Inflammatory Effects of Quercus and Other Health Benefits.

16. Jacob J, Gopalan R, Lakshmanaperumalsamy P, Illuri R, Bhosle D, Sangli GK, Mundkinajeddu D. Evaluation of Anti-psoriatic Potential of the Fruit Rind of Punica granatum L. Pharmacognosy Journal. 2019;11(3). https://doi.org/10.5530/pj.2019.11.73

Published

2025-06-15
Statistics
Abstract Display: 523
PDF Downloads: 562
PDF Downloads: 59

How to Cite

1.
Ayman U, Parveen SA, Fakeha FK. Traditional Wisdom Meets Chronic Disease: Unani Success in Managing Psoriasis with Zimad and Leech Therapy-A Case Report. J. Drug Delivery Ther. [Internet]. 2025 Jun. 15 [cited 2026 Jan. 23];15(6):1-5. Available from: https://jddtonline.info/index.php/jddt/article/view/7214

How to Cite

1.
Ayman U, Parveen SA, Fakeha FK. Traditional Wisdom Meets Chronic Disease: Unani Success in Managing Psoriasis with Zimad and Leech Therapy-A Case Report. J. Drug Delivery Ther. [Internet]. 2025 Jun. 15 [cited 2026 Jan. 23];15(6):1-5. Available from: https://jddtonline.info/index.php/jddt/article/view/7214

Most read articles by the same author(s)