Egg Yolk Oil: A Natural Remedy for Burn Wound Healing
Abstract
Burn wounds are a significant clinical challenge due to their complexity, risk of infection, and the need for effective wound healing agents. In recent years, natural products have gained increasing attention as alternatives or adjuncts to conventional therapies. Egg yolk oil (EYO), derived from the lipid fraction of hen egg yolk, has emerged as a promising bioactive substance in the management of burn injuries. The purpose of this review is to provide an overview of the effectiveness, mechanisms of action, and possible clinical uses of egg yolk oil in the healing of burn wounds. Egg yolk oil contains essential fatty acids, phospholipids, immunoglobulins, and antioxidants, all of which contribute to its anti-inflammatory, antimicrobial, and tissue-regenerative properties.
Keywords: Egg Yolk Oil, Burn wound, Supercritical extraction, solvent extraction.
Keywords:
Egg yolk oil, Burn Wound, Solvent Extraction, Supercritical ExtractionDOI
https://doi.org/10.22270/jddt.v15i6.7191References
1. Oryan A, Alemzadeh E, Burn wound healing: present concepts, treatment strategies and future directions, Journal of Wound Care, 2017; 26(1): 5-19. https://doi.org/10.12968/jowc.2017.26.1.5 PMid:28103165
2. Yenilmez E, Basaran E, Arslan R, Berkman MS, Güven, C. Bayc UM, Yazan Y,Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment, Pharmazie,2015; 70, 67-73.
3. Kumud M and Sanju N, Hen egg yolk oil: A potential source of bioavailable lutein and zeaxanthin for skin and sun protection, World Journal of Pharmaceutical Sciences, 2017; 5(1): 71-80.
4. Deirdre C, Sameer E, Owen R, Brent W, Robert L, Burn Wound Infections, Clinical Microbiology Reviews, 2006; 19(2): 403-434. https://doi.org/10.1128/CMR.19.2.403-434.2006 PMid:16614255 PMCid:PMC1471990
5. Tianhong D, Ying YH, Sulbha KS, Javad TH, Divya BK, Michael RH, Topical Antimicrobials for Burn Wound Infections, NIH Public Access, 2010; 5(2): 124-151. https://doi.org/10.2174/157489110791233522 PMid:20429870 PMCid:PMC2935806
6. Egg Yolk Oil Market Size, Share & Trends Analysis Report by Application (Personal Care & Cosmetics, Pharmaceuticals), By Extraction Method (Ethanol Extraction, Chloroform Extraction), By Region, And Segment Forecasts, 2024 - 2030. [Report].
7. Rastegar F, Azarpira N, Amiri M, Azarpira A, The effect of Egg Yolk Oil in the Healing of Third degree burns in Rat, Iranian Red Crescent Medical Journal, 2011; 13(10):739 -743.
8. Aleksandrs K, Mara D, Solvent Extraction of Egg Oil from Liquid Egg Yolk, Foodbalt 2014; 254-256.
9. Aleksandrs K, Evita S, Mara D, The Effect of Egg Yolk Oil on The Chemical, Physical and Sensory Properties of Mayonnaise, Rural Sustainability Research, 2016; 36(330): 24-31. https://doi.org/10.1515/plua-2016-0004
10. Edirisingha DN, Sandun A, Ki Chang N, Huang X, Dong UA, Egg yolk lipids: separation, characterization, and utilization, Food Science and Biotechnology, 2022; 31:1243-1256. https://doi.org/10.1007/s10068-022-01138-4 PMid:35992319 PMCid:PMC9385935
11. Pinar I, The Effect of Egg Yolk Oil on the Mast Cell Concentration in Excisional Wound Healing of STZ-Diabetic Rats, The Eurasia Proceedings of Science, Technology, Engineering & Mathematics (EPSTEM), 2019; 8: 35-41.
12. Jürgen BH, August B, Heike B, Irina E, Stefan K, Maila R, Valentina S, Nadja Z, Cellular Responses to Egg-Oil (Charismon), Acta Medica (Hradec Králové), 2014; 57(2):41-48. https://doi.org/10.14712/18059694.2014.38 PMid:25257149
13. Kumud M, Sanju N, Hen egg yolk oil: A potential source of bioavailable lutein and zeaxanthin for skin and sun protection, World Journal of Pharmaceutical Sciences, 2017; 5(1): 71-80.
14. Ping W, Pan Y, Jianye Y, Dan H, Shunxiang L, Assessment of Egg Yolk Oil Extraction Methods of for ShiZhenKang Oil by Pharmacodynamic Index Evaluation, Molecules MDPI, 2016; 219(106): 1-10. https://doi.org/10.3390/molecules21010106 PMid:26797592 PMCid:PMC6272919
15. Hui W, Linxing Y, Show LL, Tong W, Extraction of phospholipids from egg yolk flakes using aqueous alcohols, Journal of the American Oil Chemists' Society, 2017; 94: 309-314. https://doi.org/10.1007/s11746-016-2939-x
16. Matthias S, Optimization of Solvent Extraction and Direct Transmethylation Methods for The Analysis of Egg Yolk Lipids, International Journal of Food Properties, 2006; 9: 573-581. https://doi.org/10.1080/10942910600596290
17. Vida SM, Adeleh GK, Najmeh N, Shahram R, Preclinical evaluation of the polycaprolactone polyethylene glycol electrospun nanofibers containing egg yolk oil for acceleration of full thickness burns healing, Scientific reports, 2023; 13(919): 1-12. https://doi.org/10.1038/s41598-023-28065-6 PMid:36650249 PMCid:PMC9845205
Published
Abstract Display: 1383
PDF Downloads: 2005
PDF Downloads: 68 How to Cite
Issue
Section
Copyright (c) 2025 Safiya Abdul Inamdar, Sabaanjum Faijahamad Jamadar, Saniya Rafik Tamboli, Pratiksha Rajkumar Ravankole

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

.