Suranjan Shireen (Colchicum autumnale L.): A review on medicinal utility from the perspective of Unani Medicine
Abstract
Background: Suranjan Shireen (Colchicum autumnale L.), commonly known as autumn crocus or meadow saffron, holds a prominent place in Unani medicine for its therapeutic potential in musculoskeletal and inflammatory disorders. It is a well-documented medicinal plant in both traditional Unani literature and modern pharmacology.
Objective: This review aims to comprehensively explore the pharmacognostic features, phytochemical profile, therapeutic applications, and clinical relevance of Colchicum autumnale from classical and contemporary perspectives.
Methods: Classical Unani texts were examined alongside modern scientific literature to highlight the plant’s historical uses and recent pharmacological insights.
Results: The principal bioactive compound, colchicine, exhibits potent anti-inflammatory and antimitotic properties. Traditionally, the plant has been employed in the treatment of gout (Niqras), sciatica (Irqun Nisa), and chronic joint pain (Waja‘ul Mafāsil). Modern studies confirm its efficacy in managing gout, Familial Mediterranean Fever (FMF), and inflammatory conditions. However, due to its narrow therapeutic index and known toxicity, careful dosage regulation is essential.
Conclusion: The integration of traditional Unani knowledge with modern pharmacological evidence supports the safe and effective therapeutic use of Colchicum autumnale. Future research should focus on standardization, dosage optimization, and toxicity mitigation to ensure clinical safety.
Keywords: Colchicum autumnale; Suranjan Shireen; Unani Medicine; Gout, Colchicine.
Keywords:
Colchicum autumnale, Suranjan Shireen, Unani Medicine, Acute gout, ColchicineDOI
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