Therapeutic Evaluation of Syrup Nexoliv™ for Liver Health Support

Authors

Abstract

Background: Liver disorders, ranging from hepatitis to cirrhosis, are prevalent globally due to infections, toxins, and metabolic imbalances. Traditional medicine offers numerous herbal formulations known for their hepatoprotective properties. Syrup NexolivTM is a polyherbal formulation composed of 23 medicinal plants traditionally recognized for liver protection, detoxification, and overall hepatobiliary support. This study evaluates the hepatoprotective potential of Syrup Nexoliv (SN) based on its rich phytoconstituents.

Objective: To assess the hepatoprotective effect of Syrup Nexoliv through its pharmacologically active ingredients, focusing on their synergistic roles in liver health.

Methods: Syrup Nexoliv contains key hepatoprotective herbs such as Kalmegh (Andrographis paniculata), Kutki (Picrorhiza kurroa), Punarnava (Boerhavia diffusa), and Bhui Amla (Phyllanthus niruri), known for their anti-inflammatory, antioxidant, and detoxifying properties. The formulation was evaluated through literature-based evidence highlighting individual and combined therapeutic effects of its components on hepatic cells, liver enzymes, and oxidative stress parameters.

Results: Phytochemical analysis of the ingredients revealed the presence of bioactive compounds such as andrographolides, picrosides, berberine, and glycyrrhizin, which exhibit hepatoprotective, anti-inflammatory, and antioxidant actions. These compounds help in stabilizing hepatic cell membranes, reducing elevated liver enzymes, enhancing bile secretion, and protecting against hepatotoxins. Herbal ingredients like Gilo (Tinospora cordifolia) and Mulethi (Glycyrrhiza glabra) further contribute to immune modulation and liver tissue regeneration. Collectively, these herbs demonstrate a synergistic effect in managing liver dysfunction and supporting hepatic detoxification processes.

Conclusion: Syrup Nexoliv, with its comprehensive blend of hepatoprotective herbs, presents a promising natural therapeutic option for preventing and managing liver disorders. Further clinical studies are warranted to validate its efficacy and safety in liver disease patients, along with its potential role as an adjunct to conventional hepatoprotective therapies.

Keywords: Liver disorders, herbal formulations, Syrup Nexoliv

Keywords:

Liver disorders, herbal formulations, Syrup Nexoliv

DOI

https://doi.org/10.22270/jddt.v15i5.7121

Author Biographies

Md Anzar Alam, Department of Medicine, School of Unani Medical Education and Research (SUMER), Jamia Hamdard, New Delhi.

Department of Medicine, School of Unani Medical Education and Research (SUMER), Jamia Hamdard, New Delhi.

Barkati Md Tarique, Department of AYUSH, All India Institute of Medical Sciences (AIIMS) Bhopal, Madhya Pradesh.

Department of AYUSH, All India Institute of Medical Sciences (AIIMS) Bhopal, Madhya Pradesh. 

Arvind Kumar, Department of Oncology, Buddha Cancer Centre, Patna, Bihar.

Department of Oncology, Buddha Cancer Centre, Patna, Bihar. 

Raghavendara Kumar Sharma, Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS) Jodhpur, Rajasthan.

Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS) Jodhpur, Rajasthan. 

Mohd Aleemuddin Quamri, Department of Medicine, National institute of Unani Medicine, Bengaluru, Karnataka.

Department of Medicine, National institute of Unani Medicine, Bengaluru, Karnataka.

Khalid Eqbal, Department of Medicine, Sufia Unani Medical College, Hospital & Research Centre, East Champaran, Bihar.

Department of Medicine, Sufia Unani Medical College, Hospital & Research Centre, East Champaran, Bihar. 

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How to Cite

1.
Alam MA, Tarique BM, Kumar A, Sharma RK, Quamri MA, Eqbal K. Therapeutic Evaluation of Syrup Nexoliv™ for Liver Health Support. J. Drug Delivery Ther. [Internet]. 2025 May 15 [cited 2025 Nov. 12];15(5):123-31. Available from: https://jddtonline.info/index.php/jddt/article/view/7121

How to Cite

1.
Alam MA, Tarique BM, Kumar A, Sharma RK, Quamri MA, Eqbal K. Therapeutic Evaluation of Syrup Nexoliv™ for Liver Health Support. J. Drug Delivery Ther. [Internet]. 2025 May 15 [cited 2025 Nov. 12];15(5):123-31. Available from: https://jddtonline.info/index.php/jddt/article/view/7121