Nanotechnology in Drug Delivery System: A New Approach

Authors

  • Sanket P. Shinde Assistant Professor, Department of Quality Assurance Techniques, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216. https://orcid.org/0009-0003-9817-3697
  • Christopher Benjamin Lobo Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.
  • Harshal Suresh Singh Rajput Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.
  • Gaurav Fulchand Nikam Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Abstract

An extensive examination of the prior developments of drug delivery systems (DDS) based on nanoparticles will be covered in this study, along with novel research findings on the therapeutic improvement of antiretroviral therapy. Practitioners will be able to provide medications to target particular body parts thanks to the use of nanoparticle DDS. The application of nanoparticles as a DDS is having a discernible therapeutic impact in the treatment of cancers. DDS will also be used in medical imaging to illuminate brain function, cancers, or other body cellular activities. There is great promise for using nanoparticle DDS to enhance human health. Its unique features, such as its nanoscale structure, improved permeability and retention capacity, higher surface-area-to-volume ratio, ability to be functionalized on the surface etc., make it a successful drug delivery method for the administration of antiviral treatments. The more important variables that impact target-specific drug delivery, optimal cellular uptake, degree of opsonization by host immune cells, drug retention time, transcytosis, biological half-life extension, in vivo stability, and cytotoxicity are nevertheless the size, shape, charge, and surface topology of the nanoparticles. The review will shed light on the significant obstacle of clinical safety and efficacy as well as the elaborate role of drug delivery based on nanotechnology.

Keywords: Nanotechnology, Dendrimers, Controlled drug release, Nanoparticle, Nanospheres.

Keywords:

Nanotechnology, Dendrimers, Controlled drug release, Nanoparticles, Nanospheres

DOI

https://doi.org/10.22270/jddt.v15i2.6988

Author Biographies

Sanket P. Shinde, Assistant Professor, Department of Quality Assurance Techniques, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Assistant Professor, Department of Quality Assurance Techniques, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Christopher Benjamin Lobo , Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Harshal Suresh Singh Rajput, Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Gaurav Fulchand Nikam, Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216.

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15-02-2025
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Shinde SP, Lobo CB, Rajput HSS, Nikam GF. Nanotechnology in Drug Delivery System: A New Approach. J. Drug Delivery Ther. [Internet]. 2025 Feb. 15 [cited 2025 Mar. 21];15(2):112-23. Available from: https://jddtonline.info/index.php/jddt/article/view/6988

How to Cite

1.
Shinde SP, Lobo CB, Rajput HSS, Nikam GF. Nanotechnology in Drug Delivery System: A New Approach. J. Drug Delivery Ther. [Internet]. 2025 Feb. 15 [cited 2025 Mar. 21];15(2):112-23. Available from: https://jddtonline.info/index.php/jddt/article/view/6988

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