Preparation and Evaluation of Wound Healing Gel Using Extract of Psidium guajuva Leaves and Tridax Daisy Leaves

Authors

Abstract

Wounds are physical injuries that results in an opening or breaking of the skin. Proper healing of wounds is very essential for the restoration of disrupted anatomical continuity and disturbed functional status of the skin. Wound healing is a complex but generally orderly process. Sequential waves of specialized cell types first clear the inciting injury and then progressively build the scaffolding to fill in any resulting defect. The antibacterial potential of the crude leaves extracts of Psidium guajava Linn. against some bacteria associated with surgical wound, burns, skin and soft tissue infections were investigated under different conditions. Tridax procumbens (L.) is a spreading annual herb found throughout India. The plant is a native of tropical America and naturalized in tropical Africa, Asia, and Australia. Local people known it as “Ghamara,” in English popularly called “coat buttons” and is dispensed for “Bhringraj” by some of the practitioners of Ayurveda. The plant has many pharmacological applications such as hepatoprotective activity, anti-infl ammatory, wound healing, anti-diabetic activity, hypotensive effect, immunomodulating property, bronchial catarrh, dysentery, and diarrhea and to prevent falling of hair promotes the growth of hair, and antimicrobial activity against both Gram-positive and Gram-negative bacteria. The leaf juice possesses antiseptic, insecticidal and parasiticidal properties, as a remedy against conjunctivitis and is used also to check hemorrhage from cuts, bruises and wounds insect repellent.

Keywords: Preparation, Evaluation, pharmacological effect, Wound Healing Gel, Antiseptic.

Keywords:

Preparation, Evaluation, Pharmacological effect, Wound healing gel, antiseptic

DOI

https://doi.org/10.22270/jddt.v15i1.6960

Author Biographies

Kiran P. Bhosale , Assistant Professor, Department of Pharmaceutical Technology, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Assistant Professor, Department of Pharmaceutical Technology, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Priya S. Daingade , Assistant Professor, Department of Pharmaceutics, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Assistant Professor, Department of Pharmaceutics, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Pranjali D. Ugale , Assistant Professor, Department of Pharmaceutics, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Assistant Professor, Department of Pharmaceutics, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Vaishali G. Mundhe, Assistant Professor, Department of Quality Assurance Technology, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Assistant Professor, Department of Quality Assurance Technology, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Tushar T. Shelke, Principal, Department of Pharmacology, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

Principal, Department of Pharmacology, Genba Sopanrao Moze College of Pharmacy, Wagholi, Pune

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Published

15-01-2025
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How to Cite

1.
Bhosale KP, Daingade PS, Ugale PD, Mundhe VG, Shelke TT. Preparation and Evaluation of Wound Healing Gel Using Extract of Psidium guajuva Leaves and Tridax Daisy Leaves. J. Drug Delivery Ther. [Internet]. 2025 Jan. 15 [cited 2025 Feb. 7];15(1):117-24. Available from: https://jddtonline.info/index.php/jddt/article/view/6960

How to Cite

1.
Bhosale KP, Daingade PS, Ugale PD, Mundhe VG, Shelke TT. Preparation and Evaluation of Wound Healing Gel Using Extract of Psidium guajuva Leaves and Tridax Daisy Leaves. J. Drug Delivery Ther. [Internet]. 2025 Jan. 15 [cited 2025 Feb. 7];15(1):117-24. Available from: https://jddtonline.info/index.php/jddt/article/view/6960

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