PHARMACOGNOSTICAL AND PHYSICO-CHEMICAL EVALUATION OF KRISHNADI TAILA - A POLY HERBAL COMPOUND IN THE MANAGEMENT OF ASTIGMATISM

Abstract

Background: The WHO has grouped Astigmatism and uncorrected refractive error among the leading causes(18 %) of blindness and vision impairment in the world. KRISHNADI TAILA (KT) is a poly herbal Ayurvedic formulation mentioned in Yogratnakara Netrarogadhikara. Though it is an important drug until date no pharmacognostical work is found on it. Objective: The present study was aimed at setting a standard pharmacognostical and pharmaceutical profile of KT. Materials and Methods: Study included preparation of KT following all SOPs using raw drugs, which were previously authenticated. Later, KT was subjected to pharmacognostical, physicochemical and high performance thin-layer chromatography (HPTLC) analysis as per standard protocols. Results: The final observations were recorded. Pharmacognostical findings matched with that of individual raw drugs with no major change in the microscopic structure of the raw drugs during preparation of Ghana Vati. HPTLC gave the fingerprint of the formulation with ten and eight spots on short and long UV, respectively. Conclusion: This shows presence of certain constituents in the powder and is helpful for the easy separation of these constituents.

 

Keywords : Krishnadi Taila, Astigmatism, Phyto-Constituents, HPTLC.