Comprehensive Investigation of Juniperus virginiana Essential Oil: GC/MS Analysis, Thermoanalytical Characterization, and Evaluation of Bioactive Potential

Authors

Abstract

Due to the ever-increasing unregulated antibiotic use, there have been increased risks of antibiotic-resistant bacterial infections. Natural agents, their products, and derivatives have been used for centuries to cure a variety of ailments. In the present study, an attempt was made to explore the physiochemical properties of the CEO. GC-MS analysis was used to identify the volatile components present in the oil. Additionally, TGA and DSC analysis were carried out to understand the thermal properties of the oil.  The oil was characterized by higher amounts of terpenoids. The essential oil has potent anticancer, cytotoxic, antimalarial, and anti-inflammatory activity. This study concludes that the Juniperus virginiana essential oil could be used as a therapeutic agent.

Keywords: Anticancer, Antioxidant, Cedarwood, Cytotoxicity, Essential oil

Keywords:

Anticancer, Antioxidant, Cedarwood, Cytotoxicity, Essential oil, Anticancer, Antioxidant, Cedarwood, Cytotoxicity, Essential oil

DOI

https://doi.org/10.22270/jddt.v14i2.6368

Author Biographies

Vikas Jha, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Prakruti Kapadia, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Anjali Bhosale, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Simeen Rumani, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Reetikesh Patel, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Arpita Marick, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Anjali Mange, Department of Biotechnology, Guru Nanak Khalsa College, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Department of Biotechnology, Guru Nanak Khalsa College, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Kavita Nalawade, Department of Bioanalytical Sciences, Guru Nanak Khalsa College, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Department of Bioanalytical Sciences, Guru Nanak Khalsa College, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Habil Hirkani, VES Pharmacy: VES College Of Pharmacy, Collector Colony, Chembur, Mumbai, Maharashtra 400074, India

VES Pharmacy: VES College Of Pharmacy, Collector Colony, Chembur, Mumbai, Maharashtra 400074, India

Simran Gohil, Department of Bioanalytical Sciences, Guru Nanak Khalsa College, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Department of Bioanalytical Sciences, Guru Nanak Khalsa College, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

Ira Kode, National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

National Facility for Biopharmaceuticals, Guru Nanak Khalsa college, Nathalal Parekh Marg, Mumbai, Maharashtra 400019, India

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15-02-2024
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How to Cite

1.
Jha V, Kapadia P, Bhosale A, Rumani S, Patel R, Marick A, et al. Comprehensive Investigation of Juniperus virginiana Essential Oil: GC/MS Analysis, Thermoanalytical Characterization, and Evaluation of Bioactive Potential. J. Drug Delivery Ther. [Internet]. 2024 Feb. 15 [cited 2025 Feb. 13];14(2):102-1. Available from: https://jddtonline.info/index.php/jddt/article/view/6368

How to Cite

1.
Jha V, Kapadia P, Bhosale A, Rumani S, Patel R, Marick A, et al. Comprehensive Investigation of Juniperus virginiana Essential Oil: GC/MS Analysis, Thermoanalytical Characterization, and Evaluation of Bioactive Potential. J. Drug Delivery Ther. [Internet]. 2024 Feb. 15 [cited 2025 Feb. 13];14(2):102-1. Available from: https://jddtonline.info/index.php/jddt/article/view/6368

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