Adult Onset Still’s Disease in a Patient with Fever of Unknown Origin: A Rare Case

  • Silky Kumari Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India https://orcid.org/0009-0002-2204-7072
  • Subhankar Das Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India https://orcid.org/0000-0003-3753-5810
  • Sudha Kumari Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India https://orcid.org/0009-0005-9528-9904
  • Gyan Ranjan Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India https://orcid.org/0009-0006-3335-4173
  • Mahaprasad Barik Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India
  • Ramya Ranjan Kanta Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India
  • Somnath Nishad Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Abstract

Adult onset Still’s disease (AOSD) is a rare clinical entity with unknown etiology, characterized by arthritis, fever, evanescent rash, and other systemic presentations. AOSD generally does not overlap with other rheumatic diseases. AOSD is a diagnosis by exclusion, and it is one of the common causes of pyrexia of unknown origin (PUO) which can be life-threatening if mistreated. Although steroids are the first line of therapy, about 20%-30% of patients are refractory, intolerant, and or relapse during tapering or upon discontinuation of steroids. There are no clinical guidelines in treating such patients, which is challenging.


Keywords:  Still’s disease, arthritis, fever, auto-inflammatory

Keywords: Still’s disease, arthritis, fever, auto-inflammatory

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Author Biographies

Silky Kumari, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

Subhankar Das, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

Sudha Kumari, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

Gyan Ranjan, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

Mahaprasad Barik, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

Ramya Ranjan Kanta, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

Somnath Nishad, Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University. 302017, Jaipur, Rajasthan, India

Department of  Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University.  302017, Jaipur, Rajasthan, India

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1.
Kumari S, Das S, Kumari S, Ranjan G, Barik M, Kanta RR, Nishad S. Adult Onset Still’s Disease in a Patient with Fever of Unknown Origin: A Rare Case. JDDT [Internet]. 15Jan.2024 [cited 25Feb.2024];14(1):1-. Available from: https://jddtonline.info/index.php/jddt/article/view/6201