Khatmī (Althea officinalis L. and Althea rosea): Medicinal importance in the perspective of Unani medicine and pharmacological studies
Abstract
Althea officinalis L. is an important Unani Medicinal plant belonging to the family Malvaceae. The herb is commonly known as Khatmī and Marsh-mallow. All parts of the plant such as seeds, leaves, root and flowers are mainly used as medicine in Unani Medicine. It is used for many pharmacological actions like diuretic, lithotriptic, deobstruent, anti-inflammatory, emmenagogue which makes it useful in treatment of kidney stone jaundice, menstrual disorder, hepatitis, headache etc. Many scientific studies are done on the pharmacological actions of this herb. In this chapter both modern and Unani perspective of pharmacological properties of Althea officinalis L. along with its Phytochemistry and pharmacological studies are included.
Keywords: Althea officinalis L.; Khatmī; Malvaceae
Keywords:
Althea officinalis L, Khatmī, MalvaceaeDOI
https://doi.org/10.22270/jddt.v13i12.6155References
Ashraf HM. Makhzan al-Mufradat. New Delhi: Aijaz Publishing House; 2011, pp. 116.
Ibn Sina. Al-Qanun Fi Al-Tibb. New Delhi: English edition, Hamdard University; 1998.
Kabiruddin M. Bayaz-i-Kabir. New Delhi: Central Council for Research in Unani Medicine; 2008.
Ghani HN. Khazain al- Advia, Vol-IV. New Delhi: Central Council for Research in Unani Medicine; 2010, pp. 79-83.
Ibn Baitar. Al Jami Li Mufradat al-Advia Wa al-Aghzia. V-II. New Delhi: Central Council for Research in Unani Medicine; 2003: pp. 133-135.
Khare CP. Indian medicinal plants and illustrated dictionary. New Delhi: Springer Science+Business Media, Berlin/Heidelberg: LLC; 2007. https://doi.org/10.1007/978-0-387-70638-2 PMCid:PMC2705749
Anonymous. Medicinal Plants in Folklores of Kashmir Himalaya. New Delhi: Central Council for Research in Unani Medicine; 2001, pp. 37.
Anonymous. The Unani Pharmacopoeia of India. Part 1. Vol-V. New Delhi: Central Council for Research in Unani Medicine; 2008, 66,67,70,76-82,84, 85
Kirtikar KR and Basu BD. Indian medicinal plant. Part 3, Periodical Experts Book Agency, Delhi: 2012.
Nadkarni KM. Indian Materia Medica. Bombay: Popular Prakashan; 1989. 1.
Plants.usda.gov. USDA: https://plants.usda.gov/home/plantProfile?symbol=ALOF2; [updated 2021 May 21; cited 2021 May 21]. Available from: https://plants.usda.gov .
Fahamiya N, Shiffa M, Aslam M, Muzn F. Unani perspective of Khatmi (Althaea officinalis). Journal of Pharmacognosy and Phytochemistry, 2016; 5(6): 357-60.
Kirtikar KR and Basu BD. Indian medicinal plant. Part I. Vol-IV. New Delhi: Jayyed Press; 1987.
Kabiruddin M. Makhzan al-Mufradat. New Delhi: Aijaz Publication; 2014.
Ibn Rushd. Kitab al-Kulliyat. New Delhi: Central Council for Research in Unani Medicine; 1987, pp. 274
Nasir A. Mufradat-i-Nasiri, Takmila (Persian edition). Azimabad: Qaisari Publication; 1980. pp. 98-99.
Razi Z. Kitab-al-Hawi.Vol.-1. New Delhi: Central Council for Research in Unani Medicine); 1996.
Ibn Hubal, Kitab Al-Mukhtarat fi Al-Tibb, Vo-2. Central Council for Research in Unani Medicine New Delhi: 2005, pp. 284.
Anonymous. National Formulary of Unani medicine. Part-II. Vol-1. New Delhi: Central Council for Research in Unani Medicine; 2007, 35,136,137,139.
HifzulKabir. Introduction to Ilmul Advia. Shamsher Publisher and Distributors, Aligarh, Uttarpradesh. 2003: pp. 160
Anonymous. National Formulary of Unani medicine. Part-IV. New Delhi: Central Council for Research in Unani Medicine; 2011, 61,62,67,77,125.
Al-Snafi AE. The pharmaceutical importance of Althaea officinalis and Althaea rosea: A review. Int J Pharm Tech Res, 2013; 5(3): 1387-5.
Rastogi RP. Compendium of Indian Medicinal Plants. Vol. II. New Delhi; Central Drug Research Institute, Lucknow and National Institute of Science Communication; 1999. p. 37.
Rastogi RP. Compendium of Indian Medicinal Plants, Vol. III. New Delhi Central Drug Research Institute, Lucknow and National Institute of Science Communication; 1999. p. 36.
Gruenwald J, Brendler T, Jaenicke C. PDR for herbal medicines. Thomson, Reuters; 2007. p. 505.
Anonymous. The wealth of India, Vol. I. New Delhi: CSIR; 2002. p. 207,208.
Valizadeh R, Hemmati AA, Houshmand G, Bayat S, Bahadoram M. Wound healing potential of Althaea officinalis flower mucilage in rabbit full thickness wounds, Asian Pacific Journal of Tropical Biomedicine, 2015; 5(11): 937-943. https://doi.org/10.1016/j.apjtb.2015.07.018
Sutovska M, Nosalova G, Franova S, Kardosova A. The antitussive effect of polysaccharide from Althaea officinalis L. var. Robusta, Arctium lappa L. var, Herkules, and Prunus persica L. Batsch. Bratisl Lek Listy, 2007; 108(2): 93-99.
Sutovska M, Capek P, Franova S, Joskova M, Sutovsky J, Marcinek J, et al. Antitussive activity of Althaea officinalis L. polysaccharide rhamnogalacturonan and its changes in guinea pigs with oval bumine-induced airways inflammation. Bratisl Lek Listy, 2011; 112(12): 670-675.
Sadighara P, Gharibi S, Jafari AM, Khaniki GJ, Salari S. The antioxidant and Flavonoids contents of Althaea officinalis L. flowers based on their colour. Avicenna Journal of Phytomedicine Summer, 2012; 2(3): 113-117.
Benbassat N, Yoncheva K, Hadjimitova V, Hristova N, Konstantinov S, Lambov N. Influence of the extraction solvent on antioxidant activity of Althaea officinalis L. root extracts, Central European Journal of Biology, 2014; 9(2): 182-188. https://doi.org/10.2478/s11535-013-0245-2
Tabarsa M, Anvari M, Joyner HS, Behnam S, Tabarsa A. Rheological behaviour and antioxidant activity of a highly acidic gum from Althaea officinalis flower. Food Hydrocolloids, 2017; 69: 432-9. https://doi.org/10.1016/j.foodhyd.2017.02.009
European Medicines Agency Evaluation of Medicines for Human Use. London: Assessment report on Althaea officinalis L. Radix.Doc. Ref.: MEA/HMPC/98718/2008; 2009.
Valiei M, Shafaghat A and Salimi F. Chemical composition and antimicrobial activity of the flower and root hexane extracts of Althaea officinalis in Northwest Iran. Journal of Medicinal Plants Research, 2011; 5(32): 6972-697 https://doi.org/10.5897/JMPR11.963
Rashidi A, Mousavi , Reza Rahmani M., Ali Rezaee M, Hosaini W, Motaharinia Y, et al. Evaluation of antifungal effect of Lavandula officinalis, Salvia officinalis L., Sumac, Glycyrrhiza glabra, and Althaea officinalis extracts on Aspergillus niger, Aspergillusfumigatus, and Aspergillusflavus species. Journal of Medicinal Plants Research, 2011; 6(2):309-313 https://doi.org/10.5897/JMPR11.1458
Naovi SA, Khan MS, and Vohora SB. Antibacterial, anti-fungal and anthelmintic investigations on Indian medicinal plants.Fitoterapia, 1991; 62(3): 221-228
Yamada H. Relationship between chemical structure and anti-complementary activity of plant polysaccharides. Carbohydrate Research, 1985; 144:101-111. https://doi.org/10.1016/0008-6215(85)85011-4
Ding Z, Dai Y, Hao H, Pan R, Yao X, Wang Z. Anti-inflammatory effects of scopoletin and underlying mechanisms. Pharm Biol, 2009; 46(12): 854-860. https://doi.org/10.1080/13880200802367155
Ali Shah SM, Akhtar N, Akram M, Akhtar Shah P, Saeed T, Ahmed K and Asif HM. Pharmacological activity of Althaea officinalis L. Journal of Medicinal Plants Research, 2011; 5(24):5662-5666.
Müller-Limmroth W and Fröhlich HH. Wirkungsnachweis einiger phytotherapeutischer Expektorantien auf den mukoziliaren Transport. Fortschritte der Medizin; 1980. 95, 98-101.
Roshangar F, Modaresi M, Toghyani M. Effect of Marshmallow's Root Extract on Thyroid Hormones in Broilers. Research Journal of Applied Sciences, Engineering and Technology, 2014; 7(1): 161-4. https://doi.org/10.19026/rjaset.7.234
Zoobi J, Mohd A. Hepatoprotective activity of ethanolic extract of Althaea officinalis Linn against carbon tetrachloride induced hepatotoxicity on albino Wistar rats. International Research Journal of Pharmacy, 2011; 2(12): 154-156.
Rezaei M, Alirezaei M. Protective effects of Althaea officinalis L. extract in 6-hydroxydopamine-induced hemiParkinsonism model: behavioural, biochemical and histochemical evidence. The Journal of Physiological Sciences, 2014; 64(3): 171-6. https://doi.org/10.1007/s12576-014-0305-z PMid:24464760
Naz R, Anis M, Alatar AA. Embling production in Althaea officinalis L., through somatic embryogenesis and their appraisal via histological and scanning electron microscopical studies. Applied biochemistry and biotechnology, 2017; 182(3): 1182-97. https://doi.org/10.1007/s12010-016-2391-2 PMid:28101788
Banaee M, Fallahpour F, Soleimany V, Haghi BN. Preclinical toxicity and safety evaluation of Althaea officinalis L. extract as naturopathic medicine in common carp (Cyprinus carpio L.): Haematological and biochemical study. Journal of Applied Aquaculture, 2016; 28(2): 92-109. https://doi.org/10.1080/10454438.2016.1172285
Published
Abstract Display: 756 
PDF Downloads: 691 PDF Downloads: 166 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.